DK179788D0 - N-aryl-piperazinalkanamidderivater, fremgangsmaade til fremstilling deraf, praeparater indeholdende samme samt anvendelse af saadanne derivater til fremstilling af farmaceutisk aktive praeparater - Google Patents
N-aryl-piperazinalkanamidderivater, fremgangsmaade til fremstilling deraf, praeparater indeholdende samme samt anvendelse af saadanne derivater til fremstilling af farmaceutisk aktive praeparaterInfo
- Publication number
- DK179788D0 DK179788D0 DK179788A DK179788A DK179788D0 DK 179788 D0 DK179788 D0 DK 179788D0 DK 179788 A DK179788 A DK 179788A DK 179788 A DK179788 A DK 179788A DK 179788 D0 DK179788 D0 DK 179788D0
- Authority
- DK
- Denmark
- Prior art keywords
- 6alkyl
- derivatives
- preparing
- preparations
- piperazinal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Photolithography (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK200300404A DK175244B1 (da) | 1987-04-01 | 2003-03-17 | N-aryl-piperazinalkanamidderivater, farmaceutiske sammensætninger indeholdende disse samt fremgangsmåder til fremstilling deraf |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3412987A | 1987-04-01 | 1987-04-01 | |
US3412987 | 1987-04-01 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK179788D0 true DK179788D0 (da) | 1988-03-30 |
DK179788A DK179788A (da) | 1988-10-02 |
DK174878B1 DK174878B1 (da) | 2004-01-12 |
Family
ID=21874492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198801797A DK174878B1 (da) | 1987-04-01 | 1988-03-30 | Anvendelse af N-aryl-piperazinalkanamidderivater til fremstilling af et medikament til forbedring af søvn |
Country Status (21)
Country | Link |
---|---|
EP (2) | EP0727421B1 (da) |
JP (1) | JP2574377B2 (da) |
KR (1) | KR960016539B1 (da) |
AT (2) | ATE207474T1 (da) |
AU (1) | AU609790B2 (da) |
CA (1) | CA1315790C (da) |
DE (2) | DE3855520T2 (da) |
DK (1) | DK174878B1 (da) |
ES (2) | ES2167510T3 (da) |
FI (1) | FI97617C (da) |
GR (1) | GR3020983T3 (da) |
HK (1) | HK1006020A1 (da) |
HU (2) | HUT57740A (da) |
IE (1) | IE81057B1 (da) |
IL (1) | IL85919A (da) |
NO (1) | NO178660C (da) |
NZ (1) | NZ223847A (da) |
PH (1) | PH25507A (da) |
PT (1) | PT87118B (da) |
RU (1) | RU2014328C1 (da) |
ZA (1) | ZA882352B (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840896A (en) * | 1989-11-22 | 1998-11-24 | Janssen Pharmaceutica, N.V. | Method of preventing or limiting reperfusion damage |
CA2044143C (en) * | 1989-11-22 | 2002-11-19 | Herman Van Belle | Method of preventing or limiting reperfusion damage |
JP2660086B2 (ja) * | 1990-07-03 | 1997-10-08 | 明治製菓株式会社 | 脳及び心機能障害改善剤 |
US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
ATE174913T1 (de) * | 1992-07-31 | 1999-01-15 | Bristol Myers Squibb Co | Diphenyl oxazole-, thiazole- und imidazole- derivate als inhibitoren der wiederaufnahme des adenosins |
SE9202266D0 (sv) * | 1992-07-31 | 1992-07-31 | Kabi Pharmacia Ab | Novel piperazine carboxamides |
ES2151960T3 (es) * | 1994-04-20 | 2001-01-16 | Lonza Ag | Procedimiento para la preparacion de derivados de acido 2-piperazincarboxilicos. |
CA2234342A1 (en) * | 1997-04-10 | 1998-10-10 | Kyowa Hakko Kogyo Co., Ltd. | Pancreatitis remedy |
JP2002504134A (ja) * | 1997-06-16 | 2002-02-05 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 疼痛を治療するためのドラフラジン類似体の使用 |
UA89503C2 (uk) | 2004-09-13 | 2010-02-10 | Х. Луннбек А/С | Заміщені похідні аніліну |
ES2639621T3 (es) | 2004-12-30 | 2017-10-27 | Janssen Pharmaceutica N.V. | Derivados de fenilamida del ácido 4-(bencil)-piperazina-1-carboxílico y compuestos relacionados como moduladores de la amida hidrolasa de ácidos grasos (FAAH) para el tratamiento de la ansiedad, el dolor y otras afecciones |
UA108233C2 (uk) | 2010-05-03 | 2015-04-10 | Модулятори активності гідролази амідів жирних кислот | |
CN110511220B (zh) * | 2018-05-22 | 2022-04-01 | 上海挚盟医药科技有限公司 | 作为钾通道调节剂的对二氨基苯衍生物、其制备方法及其在医药上的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1795375A1 (de) * | 1968-09-21 | 1972-01-05 | Boehringer Mannheim Gmbh | Basische AEther und Verfahren zur Herstellung derselben |
US4766125A (en) * | 1981-06-23 | 1988-08-23 | Janssen Pharmaceutica N.V. | N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia |
-
1988
- 1988-03-10 NZ NZ223847A patent/NZ223847A/xx unknown
- 1988-03-16 CA CA000561610A patent/CA1315790C/en not_active Expired - Lifetime
- 1988-03-29 ES ES96200236T patent/ES2167510T3/es not_active Expired - Lifetime
- 1988-03-29 NO NO881407A patent/NO178660C/no not_active IP Right Cessation
- 1988-03-29 AU AU13847/88A patent/AU609790B2/en not_active Expired
- 1988-03-29 DE DE3855520T patent/DE3855520T2/de not_active Expired - Lifetime
- 1988-03-29 AT AT96200236T patent/ATE207474T1/de not_active IP Right Cessation
- 1988-03-29 DE DE3856501T patent/DE3856501T2/de not_active Expired - Lifetime
- 1988-03-29 ES ES88200587T patent/ES2091183T3/es not_active Expired - Lifetime
- 1988-03-29 AT AT88200587T patent/ATE142627T1/de not_active IP Right Cessation
- 1988-03-29 EP EP96200236A patent/EP0727421B1/en not_active Expired - Lifetime
- 1988-03-29 EP EP88200587A patent/EP0285219B1/en not_active Expired - Lifetime
- 1988-03-30 IL IL85919A patent/IL85919A/xx not_active IP Right Cessation
- 1988-03-30 PT PT87118A patent/PT87118B/pt not_active IP Right Cessation
- 1988-03-30 DK DK198801797A patent/DK174878B1/da not_active IP Right Cessation
- 1988-03-30 KR KR1019880003493A patent/KR960016539B1/ko not_active IP Right Cessation
- 1988-03-30 PH PH36714A patent/PH25507A/en unknown
- 1988-03-31 FI FI881525A patent/FI97617C/fi not_active IP Right Cessation
- 1988-03-31 RU SU884355523A patent/RU2014328C1/ru active
- 1988-03-31 JP JP63076629A patent/JP2574377B2/ja not_active Expired - Lifetime
- 1988-03-31 ZA ZA882352A patent/ZA882352B/xx unknown
- 1988-03-31 HU HU881601A patent/HUT57740A/hu unknown
- 1988-03-31 IE IE98988A patent/IE81057B1/en not_active IP Right Cessation
-
1995
- 1995-06-20 HU HU95P/P00287P patent/HU211129A9/hu unknown
-
1996
- 1996-09-12 GR GR960402273T patent/GR3020983T3/el unknown
-
1998
- 1998-06-11 HK HK98105168A patent/HK1006020A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |