DK174885A - Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse - Google Patents

Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse Download PDF

Info

Publication number: DK174885A
Authority: DK; Denmark
Prior art keywords: compounds; phenylmethylthio; oxopropyl; enantiomers; procedures
Prior art date: 1984-04-19

Application number

DK174885A

Other languages

English (en)

Other versions

DK174885D0 (da

Inventor

Jacques Comarmond

Luc Rivron

Thomas Purcell

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-19

Filing date

1985-04-18

Publication date

1985-10-20

1984-04-19 Priority claimed from FR8406201A external-priority patent/FR2563219B1/fr

1984-04-19 Priority claimed from FR8406200A external-priority patent/FR2563218B1/fr

1985-04-18 Application filed by Synthelabo filed Critical Synthelabo

1985-04-18 Publication of DK174885D0 publication Critical patent/DK174885D0/da

1985-10-20 Publication of DK174885A publication Critical patent/DK174885A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

der omsættes med mercaptopropionsyre og videre med thionyl-chlorid og tilsidst med en aminosyre HoNCHCOOH og eventuel

^ I

«2 udskiftning af og/eller saltdannelse.

Forbindelserne anvendes som mucolytiske midler, ligesom de udviser andre fysiologiske herunder analgetiske aktiviteter.

DK174885A 1984-04-19 1985-04-18 Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse DK174885A (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR8406200		1984-04-19
FR8406201		1984-04-19
FR8406201A FR2563219B1 (fr)	1984-04-19	1984-04-19	Derives d'acide n-(phenylmethylthio-3 oxo-1 propyl)- aminoacetique, leur preparation et leur application en therapeutique
FR8406200A FR2563218B1 (fr)	1984-04-19	1984-04-19	Derives d'acide n-((chloro-2 phenyl)methylthio-3 oxo-1 propyl)-aminoacetique substitue en a, leur preparation et leur application en therapeutique

Publications (2)

Publication Number	Publication Date
DK174885D0 DK174885D0 (da)	1985-04-18
DK174885A true DK174885A (da)	1985-10-20

Family

ID=26223924

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK174885A DK174885A (da)	1984-04-19	1985-04-18	Derivater af n-(3-phenylmethylthio-1-oxopropyl)-aminoeddikesyre i form af enantiomere eller blandinger, fremgangsmaade til fremstilling af forbindelserne og laegemiddel indeholdende disse

Country Status (10)

Country	Link
EP (1)	EP0161172A1 (da)
AU (1)	AU4138685A (da)
DK (1)	DK174885A (da)
ES (1)	ES8603395A1 (da)
FI (1)	FI851550L (da)
GR (1)	GR850951B (da)
HU (1)	HUT38094A (da)
IL (1)	IL74956A0 (da)
NO (1)	NO851546L (da)
PT (1)	PT80316B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3672130D1 (de) *	1985-04-19	1990-07-26	Smithkline Beecham Corp	Leukotrien-antagonisten.
US5196563A (en) *	1986-12-17	1993-03-23	Ciba-Geigy Corporation	N-phenyl-N-carboxythioureas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH451186A (de) *	1961-11-02	1968-05-15	Santen Phamarceutical Co Ltd	Verfahren zur Herstellung von N-Mercaptopropionylglycin und dessen Derivaten
JPS535112A (en) *	1976-03-08	1978-01-18	Santen Pharmaceutical Co Ltd	New cysteine derivatives
IT1111384B (it) *	1978-12-21	1986-01-13	Sigma Tau Ind Farmaceuti	Guaiacil esteri di derivati dello acido mercaptopropionico procedimento per la loro preparazione e loro uso terapeutico

1985
- 1985-04-11 EP EP85400723A patent/EP0161172A1/fr not_active Withdrawn
- 1985-04-17 IL IL74956A patent/IL74956A0/xx unknown
- 1985-04-18 PT PT80316A patent/PT80316B/pt not_active IP Right Cessation
- 1985-04-18 HU HU851499A patent/HUT38094A/hu unknown
- 1985-04-18 DK DK174885A patent/DK174885A/da not_active Application Discontinuation
- 1985-04-18 ES ES542379A patent/ES8603395A1/es not_active Expired
- 1985-04-18 FI FI851550A patent/FI851550L/fi not_active Application Discontinuation
- 1985-04-18 NO NO851546A patent/NO851546L/no unknown
- 1985-04-18 GR GR850951A patent/GR850951B/el unknown
- 1985-04-18 AU AU41386/85A patent/AU4138685A/en not_active Abandoned

Also Published As

Publication number	Publication date
EP0161172A1 (fr)	1985-11-13
ES542379A0 (es)	1985-12-16
DK174885D0 (da)	1985-04-18
IL74956A0 (en)	1985-08-30
NO851546L (no)	1985-10-21
HUT38094A (en)	1986-04-28
FI851550L (fi)	1985-10-20
PT80316B (fr)	1987-02-16
AU4138685A (en)	1985-10-24
PT80316A (fr)	1985-05-01
GR850951B (da)	1985-11-25
FI851550A0 (fi)	1985-04-18
ES8603395A1 (es)	1985-12-16

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Legal Events

Date	Code	Title	Description
1987-12-14	AHB	Application shelved due to non-payment