DK174745B1 - Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier - Google Patents
Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier Download PDFInfo
- Publication number
- DK174745B1 DK174745B1 DK198701785A DK178587A DK174745B1 DK 174745 B1 DK174745 B1 DK 174745B1 DK 198701785 A DK198701785 A DK 198701785A DK 178587 A DK178587 A DK 178587A DK 174745 B1 DK174745 B1 DK 174745B1
- Authority
- DK
- Denmark
- Prior art keywords
- acid
- triiodo
- reaction
- mmol
- added
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Photoreceptors In Electrophotography (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76427485A | 1985-08-09 | 1985-08-09 | |
US76427485 | 1985-08-09 | ||
US8601590 | 1986-08-01 | ||
PCT/US1986/001590 WO1987000757A1 (en) | 1985-08-09 | 1986-08-01 | Non-ionic polyol contrast media from ionic contrast media |
Publications (3)
Publication Number | Publication Date |
---|---|
DK178587D0 DK178587D0 (da) | 1987-04-08 |
DK178587A DK178587A (da) | 1987-04-08 |
DK174745B1 true DK174745B1 (da) | 2003-10-13 |
Family
ID=25070222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198701785A DK174745B1 (da) | 1985-08-09 | 1987-04-08 | Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0233249B1 (no) |
JP (1) | JPH0813794B2 (no) |
AU (3) | AU600672B2 (no) |
CA (1) | CA1339666C (no) |
DE (1) | DE3689330T2 (no) |
DK (1) | DK174745B1 (no) |
HK (1) | HK1003564A1 (no) |
NO (1) | NO178106C (no) |
WO (1) | WO1987000757A1 (no) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4109169A1 (de) * | 1991-03-20 | 1992-09-24 | Koehler Chemie Dr Franz | Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung |
US5840967A (en) * | 1996-08-29 | 1998-11-24 | Nycomed Imaging As | Process for the preparation of contrast agents |
GB9618055D0 (en) * | 1996-08-29 | 1996-10-09 | Nycomed Imaging As | Process |
AU2002245169A1 (en) | 2000-11-10 | 2002-07-08 | Wm. Marsh Rice University | Fullerene (c60)-based x-ray contrast agent for diagnostic imaging |
FR2899581B1 (fr) * | 2006-04-07 | 2008-06-27 | Guerbet Sa | Procede d'atomisation du ioxilan |
WO2010079201A1 (en) | 2009-01-09 | 2010-07-15 | Ge Healthcare As | Contrast media compositions |
PT108524B (pt) | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE392100B (sv) * | 1969-06-27 | 1977-03-14 | Nyegaard & Co As | Trijodbensoylaminer till anvendning sasom rontgenkontrastmedel eller for separation av biologiska material |
BE788054A (fr) * | 1971-08-26 | 1973-02-26 | Bracco Ind Chimica Spa | Nouvel agent de contraste radiographique et procede pour le preparer |
CH608189A5 (no) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
IT1193761B (it) * | 1978-07-04 | 1988-08-24 | Nyegaard & Co As | Procedimento per preparare una soluzione sterile stabile di un agente di cotrasto per raggi x |
DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
DE3150916A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel" |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
EP0105752B1 (en) * | 1982-10-01 | 1986-05-07 | NYEGAARD & CO. A/S | X-ray contrast agents |
-
1986
- 1986-08-01 JP JP61504213A patent/JPH0813794B2/ja not_active Expired - Lifetime
- 1986-08-01 AU AU61974/86A patent/AU600672B2/en not_active Expired
- 1986-08-01 DE DE3689330T patent/DE3689330T2/de not_active Expired - Lifetime
- 1986-08-01 WO PCT/US1986/001590 patent/WO1987000757A1/en active IP Right Grant
- 1986-08-01 EP EP19860905063 patent/EP0233249B1/en not_active Expired - Lifetime
- 1986-08-08 CA CA 515634 patent/CA1339666C/en not_active Expired - Fee Related
-
1987
- 1987-04-08 NO NO871474A patent/NO178106C/no not_active IP Right Cessation
- 1987-04-08 DK DK198701785A patent/DK174745B1/da not_active IP Right Cessation
-
1990
- 1990-11-22 AU AU66866/90A patent/AU650432B2/en not_active Expired
-
1994
- 1994-09-22 AU AU74155/94A patent/AU673286B2/en not_active Expired
-
1998
- 1998-03-27 HK HK98102656A patent/HK1003564A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK178587D0 (da) | 1987-04-08 |
CA1339666C (en) | 1998-02-10 |
AU6686690A (en) | 1991-06-13 |
DE3689330D1 (de) | 1994-01-05 |
AU6197486A (en) | 1987-03-05 |
DK178587A (da) | 1987-04-08 |
HK1003564A1 (en) | 1998-10-30 |
JPS63500522A (ja) | 1988-02-25 |
NO178106C (no) | 1996-01-24 |
DE3689330T2 (de) | 1994-05-19 |
EP0233249B1 (en) | 1993-11-24 |
EP0233249A4 (en) | 1988-10-06 |
AU7415594A (en) | 1995-01-05 |
AU650432B2 (en) | 1994-06-23 |
AU673286B2 (en) | 1996-10-31 |
WO1987000757A1 (en) | 1987-02-12 |
NO871474D0 (no) | 1987-04-08 |
EP0233249A1 (en) | 1987-08-26 |
AU600672B2 (en) | 1990-08-23 |
NO178106B (no) | 1995-10-16 |
JPH0813794B2 (ja) | 1996-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3701771A (en) | N-(2,4,6-triiodobenzoyl)-sugar amines | |
US4021481A (en) | Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups | |
US5073362A (en) | Dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides) and x-ray contrast media containing them | |
DK159772B (da) | Trijod-isophthalsyrediamider og roentgenkontrastmidler indeholdende disse forbindelser | |
DK160868B (da) | Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem | |
JPH05502230A (ja) | 非イオン性x線造影剤、組成物及び方法 | |
DK174745B1 (da) | Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier | |
IT9022088A1 (it) | 1, 3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2, 4, 6-triiodo-benzoil-amino)-idrossi- o idrossi-alchilpropani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono | |
JPH07504179A (ja) | ラジオグラフィ用造影剤に用いられる化合物 | |
DK154501B (da) | 5-amino-2,4,6-trijodisophthalsyre-bis-amid-derivater og deres salte med roentgenkontrastsyrer | |
US5191119A (en) | Process for producing non-ionic radiographic contrast media utilizing N-allylation | |
AU643447B2 (en) | Novel carboxamide non-ionic contrast media | |
JPH038333B2 (no) | ||
US5958375A (en) | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | |
US20100303734A1 (en) | Contrast agents | |
US4954348A (en) | Non-ionic polyol contrast media from ionic contrast media | |
JPH01153667A (ja) | 置換ジカルボン酸−ビス(3,5,−ジカルバモイル−2,4,6,−トリヨード−アニリド)、その製法およびこの化合物を含有するレントゲン造影剤 | |
JPS59193857A (ja) | 非イオン性ヨウド−またはブロモ−ベンゼン化合物、およびそれらを含有するx線造影剤 | |
HRP920498A2 (hr) | Postupak za pripravu novih trijodobenzenovih spojeva s neionskim jodom i kontrastnih proizvoda koji ih sadrže | |
JPH0641065A (ja) | 非イオン性放射線造影剤 | |
WO1994022810A1 (es) | Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen | |
NO178107B (no) | Fremgangsmåte for fremstilling av ikke-ioniske polyolkontrastmedier fra ioniske kontrastmedier | |
IE891800L (en) | Novel iodinated non-ionic triiodobenzene compounds and¹contrast media containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |