DK1745040T3 - Som modulatorer af dopamin-D3-receptorer anvendelige azabicyclo(3.1.0)hexanederivater - Google Patents

Som modulatorer af dopamin-D3-receptorer anvendelige azabicyclo(3.1.0)hexanederivater

Info

Publication number: DK1745040T3
Authority: DK; Denmark
Prior art keywords: azabicyclo; dopamine; modulators; receptors; derivatives useful
Prior art date: 2004-02-23

Application number

DK05707610.1T

Other languages

English (en)

Inventor

Luca Arista

Giorgio Bonanomi

Anna Maria Capelli

Federica Damiani

Fabio Romano Di

Gabriella Gentile

Dieter Hamprecht

Fabrizio Micheli

Luca Tarsi

Giovanna Tedesco

Silvia Terreni

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-23

Filing date

2005-02-21

Publication date

2010-04-12

2004-02-23 Priority claimed from GB0403990A external-priority patent/GB0403990D0/en

2004-02-24 Priority claimed from GB0404083A external-priority patent/GB0404083D0/en

2004-07-30 Priority claimed from GB0417120A external-priority patent/GB0417120D0/en

2005-02-21 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2010-04-12 Application granted granted Critical

2010-04-12 Publication of DK1745040T3 publication Critical patent/DK1745040T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
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- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK05707610.1T 2004-02-23 2005-02-21 Som modulatorer af dopamin-D3-receptorer anvendelige azabicyclo(3.1.0)hexanederivater DK1745040T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0403990A GB0403990D0 (en)	2004-02-23	2004-02-23	Compounds
GB0404083A GB0404083D0 (en)	2004-02-24	2004-02-24	Compounds
GB0417120A GB0417120D0 (en)	2004-07-30	2004-07-30	Compounds
PCT/EP2005/001940 WO2005080382A1 (en)	2004-02-23	2005-02-21	Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors

Publications (1)

Publication Number	Publication Date
DK1745040T3 true DK1745040T3 (da)	2010-04-12

Family

ID=34890800

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK08169934.0T DK2070922T3 (da)	2004-02-23	2005-02-21	Som modulatorer af dopamin-D3-receptorer anvendelige azabicyclo(3.1.0)hexan-derivater
DK05707610.1T DK1745040T3 (da)	2004-02-23	2005-02-21	Som modulatorer af dopamin-D3-receptorer anvendelige azabicyclo(3.1.0)hexanederivater
DK08169935.7T DK2060570T3 (da)	2004-02-23	2005-02-21	Som modulatorer af dopamin-d3-receptorer anvendelige azabicyclo(3.1.0)hexanderivater

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK08169934.0T DK2070922T3 (da)	2004-02-23	2005-02-21	Som modulatorer af dopamin-D3-receptorer anvendelige azabicyclo(3.1.0)hexan-derivater

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK08169935.7T DK2060570T3 (da)	2004-02-23	2005-02-21	Som modulatorer af dopamin-d3-receptorer anvendelige azabicyclo(3.1.0)hexanderivater

Country Status (26)

Country	Link
US (3)	US7855298B2 (da)
EP (3)	EP2070922B1 (da)
JP (1)	JP4960217B2 (da)
KR (1)	KR101143718B1 (da)
CN (1)	CN1946714B (da)
AR (1)	AR047890A1 (da)
AT (3)	ATE520686T1 (da)
AU (2)	AU2005215918C1 (da)
BR (1)	BRPI0507945A (da)
CA (1)	CA2557115C (da)
CY (3)	CY1109854T1 (da)
DE (1)	DE602005018190D1 (da)
DK (3)	DK2070922T3 (da)
ES (2)	ES2337590T3 (da)
HK (1)	HK1103016A1 (da)
HR (3)	HRP20100114T1 (da)
IL (1)	IL177184A0 (da)
MA (1)	MA28438B1 (da)
NO (1)	NO20064309L (da)
PE (1)	PE20051173A1 (da)
PL (3)	PL2070922T3 (da)
PT (3)	PT1745040E (da)
RU (1)	RU2434011C2 (da)
SI (3)	SI2070922T1 (da)
TW (1)	TW200538113A (da)
WO (1)	WO2005080382A1 (da)

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GB0719234D0 (en) *	2007-10-02	2007-11-14	Glaxo Group Ltd	Novel compounds
GB0719235D0 (en) *	2007-10-02	2007-11-14	Glaxo Group Ltd	Novel compounds
CN102816106A (zh)	2008-06-24	2012-12-12	默沙东公司	用于制备基本上立体异构纯的稠合二环脯氨酸化合物的生物催化方法
NZ592297A (en)	2008-09-22	2012-11-30	Cayman Chemical Co Inc	2-Aryl-5-heteroaryl pyridine and pyrimidine derivatives as pharmaceutical active agents
CN102803224A (zh) *	2009-06-26	2012-11-28	万能药生物有限公司	新的氮杂双环己烷类化合物
US20140206740A1 (en)	2011-07-30	2014-07-24	Neurovance, Inc.	Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
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EP3331886B1 (en)	2015-08-05	2020-07-15	Indivior UK Limited	Dopamine d3 receptor antagonists having a bicyclo moiety
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GB0616574D0 (en) *	2006-08-21	2006-09-27	Glaxo Group Ltd	Compounds

2005
- 2005-02-21 CN CN2005800126155A patent/CN1946714B/zh not_active Expired - Fee Related
- 2005-02-21 SI SI200531398T patent/SI2070922T1/sl unknown
- 2005-02-21 PL PL08169934T patent/PL2070922T3/pl unknown
- 2005-02-21 ES ES05707610T patent/ES2337590T3/es not_active Expired - Lifetime
- 2005-02-21 DE DE602005018190T patent/DE602005018190D1/de not_active Expired - Lifetime
- 2005-02-21 US US10/598,200 patent/US7855298B2/en not_active Expired - Fee Related
- 2005-02-21 EP EP08169934A patent/EP2070922B1/en not_active Expired - Lifetime
- 2005-02-21 EP EP05707610A patent/EP1745040B9/en not_active Expired - Lifetime
- 2005-02-21 JP JP2007500152A patent/JP4960217B2/ja not_active Expired - Fee Related
- 2005-02-21 KR KR1020067016833A patent/KR101143718B1/ko not_active IP Right Cessation
- 2005-02-21 DK DK08169934.0T patent/DK2070922T3/da active
- 2005-02-21 AT AT08169934T patent/ATE520686T1/de active
- 2005-02-21 PE PE2005000205A patent/PE20051173A1/es not_active Application Discontinuation
- 2005-02-21 SI SI200530923T patent/SI1745040T1/sl unknown
- 2005-02-21 ES ES08169935T patent/ES2380990T3/es not_active Expired - Lifetime
- 2005-02-21 PT PT05707610T patent/PT1745040E/pt unknown
- 2005-02-21 TW TW094105108A patent/TW200538113A/zh unknown
- 2005-02-21 WO PCT/EP2005/001940 patent/WO2005080382A1/en active Application Filing
- 2005-02-21 AU AU2005215918A patent/AU2005215918C1/en not_active Ceased
- 2005-02-21 SI SI200531503T patent/SI2060570T1/sl unknown
- 2005-02-21 PT PT08169934T patent/PT2070922E/pt unknown
- 2005-02-21 RU RU2006133909/04A patent/RU2434011C2/ru not_active IP Right Cessation
- 2005-02-21 AT AT05707610T patent/ATE451364T1/de active
- 2005-02-21 DK DK05707610.1T patent/DK1745040T3/da active
- 2005-02-21 PT PT08169935T patent/PT2060570E/pt unknown
- 2005-02-21 PL PL05707610T patent/PL1745040T3/pl unknown
- 2005-02-21 EP EP08169935A patent/EP2060570B1/en not_active Expired - Lifetime
- 2005-02-21 DK DK08169935.7T patent/DK2060570T3/da active
- 2005-02-21 PL PL08169935T patent/PL2060570T3/pl unknown
- 2005-02-21 AT AT08169935T patent/ATE542816T1/de active
- 2005-02-21 CA CA2557115A patent/CA2557115C/en not_active Expired - Fee Related
- 2005-02-21 AR ARP050100632A patent/AR047890A1/es not_active Application Discontinuation
- 2005-02-21 BR BRPI0507945-4A patent/BRPI0507945A/pt active Search and Examination
2006
- 2006-07-31 IL IL177184A patent/IL177184A0/en unknown
- 2006-08-22 MA MA29286A patent/MA28438B1/fr unknown
- 2006-09-22 NO NO20064309A patent/NO20064309L/no not_active Application Discontinuation
2007
- 2007-07-12 HK HK07107486.9A patent/HK1103016A1/xx not_active IP Right Cessation
2009
- 2009-09-01 AU AU2009212887A patent/AU2009212887A1/en not_active Abandoned
- 2009-12-16 US US12/639,282 patent/US8283474B2/en not_active Expired - Fee Related
- 2009-12-16 US US12/639,129 patent/US8263782B2/en not_active Expired - Fee Related
2010
- 2010-03-01 CY CY20101100197T patent/CY1109854T1/el unknown
- 2010-03-02 HR HR20100114T patent/HRP20100114T1/hr unknown
2011
- 2011-10-26 HR HR20110781T patent/HRP20110781T1/hr unknown
- 2011-11-07 CY CY20111101073T patent/CY1112011T1/el unknown
2012
- 2012-03-29 HR HR20120281T patent/HRP20120281T1/hr unknown
- 2012-04-11 CY CY20121100356T patent/CY1113029T1/el unknown

Also Published As

Publication number	Publication date
EP1745040A1 (en)	2007-01-24
EP2060570B1 (en)	2012-01-25
AU2005215918B2 (en)	2009-06-11
MA28438B1 (fr)	2007-02-01
EP1745040B9 (en)	2010-06-02
US20070142438A1 (en)	2007-06-21
HK1103016A1 (en)	2007-12-14
RU2434011C2 (ru)	2011-11-20
IL177184A0 (en)	2006-12-10
HRP20120281T1 (hr)	2012-04-30
DE602005018190D1 (de)	2010-01-21
CY1112011T1 (el)	2015-11-04
CN1946714B (zh)	2011-06-15
EP2070922B1 (en)	2011-08-17
SI2070922T1 (sl)	2011-12-30
PL2060570T3 (pl)	2012-06-29
EP1745040B1 (en)	2009-12-09
US20100160336A1 (en)	2010-06-24
SI2060570T1 (sl)	2012-05-31
CN1946714A (zh)	2007-04-11
WO2005080382A1 (en)	2005-09-01
EP2060570A2 (en)	2009-05-20
CA2557115C (en)	2012-10-02
ATE542816T1 (de)	2012-02-15
US8283474B2 (en)	2012-10-09
AU2009212887A1 (en)	2009-09-24
DK2070922T3 (da)	2011-11-28
ES2337590T3 (es)	2010-04-27
PT2070922E (pt)	2011-11-24
ES2380990T3 (es)	2012-05-22
NO20064309L (no)	2006-11-23
US20100152195A1 (en)	2010-06-17
CY1113029T1 (el)	2016-04-13
US8263782B2 (en)	2012-09-11
AU2005215918C1 (en)	2010-01-21
ATE520686T1 (de)	2011-09-15
HRP20110781T1 (hr)	2011-11-30
PL2070922T3 (pl)	2012-01-31
AU2005215918A1 (en)	2005-09-01
HRP20100114T1 (hr)	2010-04-30
TW200538113A (en)	2005-12-01
RU2006133909A (ru)	2008-03-27
EP2060570A3 (en)	2009-06-03
BRPI0507945A (pt)	2007-07-24
EP2070922A1 (en)	2009-06-17
AR047890A1 (es)	2006-03-01
PL1745040T3 (pl)	2010-05-31
JP4960217B2 (ja)	2012-06-27
US7855298B2 (en)	2010-12-21
JP2007523208A (ja)	2007-08-16
DK2060570T3 (da)	2012-04-30
PT1745040E (pt)	2010-03-08
PE20051173A1 (es)	2006-02-14
SI1745040T1 (sl)	2010-04-30
KR101143718B1 (ko)	2012-07-05
ATE451364T1 (de)	2009-12-15
CA2557115A1 (en)	2005-09-01
KR20060127991A (ko)	2006-12-13
CY1109854T1 (el)	2014-09-10
PT2060570E (pt)	2012-05-07

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