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DK170778B1 - BU-3608 N-alkylderivater, farmaceutiske præparater med indhold deraf samt BU-3608 mellemprodukter - Google Patents

BU-3608 N-alkylderivater, farmaceutiske præparater med indhold deraf samt BU-3608 mellemprodukter Download PDF

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Publication number
DK170778B1
DK170778B1 DK354689A DK354689A DK170778B1 DK 170778 B1 DK170778 B1 DK 170778B1 DK 354689 A DK354689 A DK 354689A DK 354689 A DK354689 A DK 354689A DK 170778 B1 DK170778 B1 DK 170778B1
Authority
DK
Denmark
Prior art keywords
pharmaceutically acceptable
acceptable salts
compound according
methyl
formula
Prior art date
Application number
DK354689A
Other languages
Danish (da)
English (en)
Other versions
DK354689A (da
DK354689D0 (da
Inventor
Maki Nishio
Masatoshi Kakushima
Masataka Konishi
Toshikazu Oki
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of DK354689D0 publication Critical patent/DK354689D0/da
Publication of DK354689A publication Critical patent/DK354689A/da
Application granted granted Critical
Publication of DK170778B1 publication Critical patent/DK170778B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK354689A 1988-07-19 1989-07-18 BU-3608 N-alkylderivater, farmaceutiske præparater med indhold deraf samt BU-3608 mellemprodukter DK170778B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22114488 1988-07-19
US07/221,144 US4960755A (en) 1988-07-19 1988-07-19 BU-3608 derivatives

Publications (3)

Publication Number Publication Date
DK354689D0 DK354689D0 (da) 1989-07-18
DK354689A DK354689A (da) 1990-01-20
DK170778B1 true DK170778B1 (da) 1996-01-15

Family

ID=22826542

Family Applications (1)

Application Number Title Priority Date Filing Date
DK354689A DK170778B1 (da) 1988-07-19 1989-07-18 BU-3608 N-alkylderivater, farmaceutiske præparater med indhold deraf samt BU-3608 mellemprodukter

Country Status (23)

Country Link
US (1) US4960755A (xx)
EP (1) EP0351799B1 (xx)
JP (1) JP2772549B2 (xx)
KR (1) KR970003127B1 (xx)
AT (1) ATE100459T1 (xx)
AU (1) AU622197B2 (xx)
CA (1) CA1337907C (xx)
CS (1) CS274700B2 (xx)
DD (2) DD296081A5 (xx)
DE (1) DE68912438T2 (xx)
DK (1) DK170778B1 (xx)
ES (1) ES2048793T3 (xx)
FI (1) FI92206C (xx)
HU (2) HU203112B (xx)
IE (1) IE62586B1 (xx)
IL (1) IL91001A (xx)
MY (1) MY105128A (xx)
NO (1) NO170544C (xx)
NZ (1) NZ229964A (xx)
PT (1) PT91203B (xx)
RU (2) RU2032693C1 (xx)
YU (1) YU138289A (xx)
ZA (1) ZA895455B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114857A (en) * 1988-11-10 1992-05-19 Bristol-Myers Company Actinomadura hibisca microorganism useful for preparing serine analogs of BU-3608 antibiotics
US5183808A (en) * 1988-11-10 1993-02-02 Bristol-Myers Squibb Company Method for treating fungal infections with serine analogs of BU-3608 antibiotics
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
US5098708A (en) * 1990-06-14 1992-03-24 Bristol-Myers Squibb Company Antiviral antibiotic BU-3889V
EP0407939A1 (en) * 1989-07-10 1991-01-16 Bristol-Myers Squibb Company Antiviral antibiotic BU-3889V
US5227370A (en) * 1989-11-14 1993-07-13 Bristol-Myers Squibb Company Pradimicin derivatives
FI92207C (fi) * 1989-11-14 1994-10-10 Squibb Bristol Myers Co Menetelmä terapeuttisesti käyttökelpoisten pradimisiinijohdannaisten valmistamiseksi
CA2030166C (en) * 1989-11-22 1997-10-07 Shimpei Aburaki Pradimicin derivatives
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
US5338728A (en) * 1992-08-14 1994-08-16 Bristol-Myers Squibb Pradimicin compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4591637A (en) * 1985-01-17 1986-05-27 Sri International Open chain-morpholino adriamycins
US4870165A (en) * 1987-02-02 1989-09-26 Bristol-Myers Company Antifungal antibiotics
JP2512050B2 (ja) * 1987-12-25 1996-07-03 財団法人微生物化学研究会 新規抗かび性抗生物質デキシロシルベナノマイシンｂならびにその製造法
US5055453A (en) * 1987-11-02 1991-10-08 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Benanomicins a and antibiotic compositions
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives

Also Published As

Publication number Publication date
DE68912438D1 (de) 1994-03-03
PT91203B (pt) 1995-03-01
CS274700B2 (en) 1991-09-15
AU622197B2 (en) 1992-04-02
DE68912438T2 (de) 1994-06-01
ZA895455B (en) 1991-12-24
DK354689A (da) 1990-01-20
KR900001715A (ko) 1990-02-27
CA1337907C (en) 1996-01-09
HUT51283A (en) 1990-04-28
KR970003127B1 (ko) 1997-03-14
DD296081A5 (de) 1991-11-21
DK354689D0 (da) 1989-07-18
JP2772549B2 (ja) 1998-07-02
HU908256D0 (en) 1991-06-28
IL91001A (en) 1995-06-29
IE892325L (en) 1990-01-19
FI92206B (fi) 1994-06-30
JPH0273095A (ja) 1990-03-13
IL91001A0 (en) 1990-02-09
NO170544C (no) 1992-10-28
NO170544B (no) 1992-07-20
ES2048793T3 (es) 1994-04-01
IE62586B1 (en) 1995-02-08
HU205131B (en) 1992-03-30
NO892939L (no) 1990-01-22
US4960755A (en) 1990-10-02
NZ229964A (en) 1991-07-26
RU2026302C1 (ru) 1995-01-09
MY105128A (en) 1994-08-30
EP0351799B1 (en) 1994-01-19
ATE100459T1 (de) 1994-02-15
EP0351799A3 (en) 1991-04-24
FI893426A0 (fi) 1989-07-14
YU138289A (en) 1991-02-28
HU203112B (en) 1991-05-28
CS440889A2 (en) 1990-11-14
EP0351799A2 (en) 1990-01-24
NO892939D0 (no) 1989-07-18
AU3827489A (en) 1990-01-25
FI92206C (fi) 1994-10-10
FI893426A (fi) 1990-01-20
PT91203A (pt) 1990-02-08
DD287509A5 (de) 1991-02-28
RU2032693C1 (ru) 1995-04-10

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