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DK165787D0 - Hidtil ukendte forbindelser - Google Patents

Hidtil ukendte forbindelser

Info

Publication number
DK165787D0
DK165787D0 DK165787A DK165787A DK165787D0 DK 165787 D0 DK165787 D0 DK 165787D0 DK 165787 A DK165787 A DK 165787A DK 165787 A DK165787 A DK 165787A DK 165787 D0 DK165787 D0 DK 165787D0
Authority
DK
Denmark
Prior art keywords
unknown relationships
unknown
relationships
Prior art date
Application number
DK165787A
Other languages
English (en)
Other versions
DK165787A (da
Inventor
Michael Joseph Browne
Jeffery Hugh Robinson
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868608016A external-priority patent/GB8608016D0/en
Priority claimed from GB868608017A external-priority patent/GB8608017D0/en
Priority claimed from GB868621868A external-priority patent/GB8621868D0/en
Priority claimed from GB878704077A external-priority patent/GB8704077D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK165787D0 publication Critical patent/DK165787D0/da
Publication of DK165787A publication Critical patent/DK165787A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6459Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK165787A 1986-04-02 1987-04-01 Modificeret fibrinolytisk enzym DK165787A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB868608016A GB8608016D0 (en) 1986-04-02 1986-04-02 Compounds
GB868608017A GB8608017D0 (en) 1986-04-02 1986-04-02 Compounds
GB868621868A GB8621868D0 (en) 1986-09-11 1986-09-11 Compounds
GB878704077A GB8704077D0 (en) 1987-02-21 1987-02-21 Compounds

Publications (2)

Publication Number Publication Date
DK165787D0 true DK165787D0 (da) 1987-04-01
DK165787A DK165787A (da) 1987-10-03

Family

ID=27449752

Family Applications (1)

Application Number Title Priority Date Filing Date
DK165787A DK165787A (da) 1986-04-02 1987-04-01 Modificeret fibrinolytisk enzym

Country Status (4)

Country Link
EP (1) EP0241208A1 (da)
AU (1) AU7090887A (da)
DK (1) DK165787A (da)
PT (1) PT84588B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608020D0 (en) * 1986-04-02 1986-05-08 Beecham Group Plc Compounds
US5242819A (en) * 1986-12-05 1993-09-07 Ciba-Geigy Corporation DNA molecules encoding hybrid proteins of tissue plasminogen activator and urokinase
US5580559A (en) * 1986-12-05 1996-12-03 Ciba-Geigy Corporation Hybrid plasminogen activator
IE880255L (en) * 1987-01-30 1988-07-30 American Home Prod Des-epidermal growth factor activators.
ATE110772T1 (de) * 1987-06-04 1994-09-15 Zymogenetics Inc Mutierter t-pa mit kringle-ersatz.
IL87276A (en) * 1987-08-03 1995-07-31 Fujisawa Pharmaceutical Co Analog of tissue plasminogen activator comprising only the kringle 2 and protease domain dna encoding the same processes for the preparation thereof and pharmaceutical compositions containing the same
AU618039B2 (en) * 1987-10-29 1991-12-12 Yamanouchi Pharmaceutical Co., Ltd. Novel polypeptide compounds
EP0386240B1 (en) * 1987-10-29 1995-07-19 Yamanouchi Pharmaceutical Co. Ltd. Novel polypeptide compounds
KR970005046B1 (ko) * 1987-10-29 1997-04-11 야마노우찌 세이야꾸 가부시끼가이샤 개량형 조직 플라스미노겐 활성화 인자
US5094953A (en) * 1988-03-21 1992-03-10 Genentech, Inc. Human tissue plasminogen activator variants
US5270198A (en) * 1988-05-20 1993-12-14 Genentech, Inc. DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
US5346824A (en) * 1988-05-20 1994-09-13 Genentech, Inc. DNA encoding variants of tissue plasminogen activators and expression vectors and hosts thereof
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
DE3830734A1 (de) * 1988-09-09 1990-03-22 Basf Ag Neue polypeptide, ihre herstellung und verwendung
ATE123057T1 (de) * 1988-10-27 1995-06-15 Tno Trombolytischer wirkstoff mit modifikation der domäne der kringle.
WO1991015235A1 (en) * 1990-03-30 1991-10-17 Survival Technology, Inc. t-PA ENHANCER PROFILE
EP0542869B1 (en) * 1990-07-31 1995-09-13 Genentech, Inc. Tissue plasminogen activator variants with decreased clearance
US5246850A (en) * 1990-07-31 1993-09-21 Genentech, Inc. DNA molecules encoding human tissue plasminogen activator variants with decreased clearance, vectors, and host cells
PT786257E (pt) 1992-06-03 2003-12-31 Genentech Inc Variantes de glicosilacao do activador de plasminogenio tissular com propriedades terapeuticas meloradas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
EP0201153A3 (en) * 1985-02-09 1987-10-07 Beecham Group Plc Modified enzyme and process for its preparation
ES8801374A1 (es) * 1985-04-04 1988-01-01 Beecham Group Plc Un procedimiento para preparar un activante de plasminogeno.
EP0199574B1 (en) * 1985-04-22 1991-10-23 Genentech, Inc. Human tissue plasminogen activator mutants, methods and intermediates therefor, and compositions using such mutants

Also Published As

Publication number Publication date
AU7090887A (en) 1987-10-08
PT84588A (en) 1987-04-01
DK165787A (da) 1987-10-03
PT84588B (en) 1989-05-09
EP0241208A1 (en) 1987-10-14

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Legal Events

Date Code Title Description
PUP Patent expired