DK162639C - Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddel - Google Patents
Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddelInfo
- Publication number
- DK162639C DK162639C DK493384A DK493384A DK162639C DK 162639 C DK162639 C DK 162639C DK 493384 A DK493384 A DK 493384A DK 493384 A DK493384 A DK 493384A DK 162639 C DK162639 C DK 162639C
- Authority
- DK
- Denmark
- Prior art keywords
- antitumum
- bis
- procedures
- preparing
- agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58204448A JPS6097963A (ja) | 1983-10-31 | 1983-10-31 | ビス−ジオキソピペラジン誘導体，その製造方法及びそれからなる抗腫瘍剤 |
| JP20444883 | 1983-10-31 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK493384D0 DK493384D0 (da) | 1984-10-16 |
| DK493384A DK493384A (da) | 1985-05-01 |
| DK162639B DK162639B (da) | 1991-11-25 |
| DK162639C true DK162639C (da) | 1992-04-13 |
Family
ID=16490690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK493384A DK162639C (da) | 1983-10-31 | 1984-10-16 | Bis-dioxopiperazin-derivater, fremgangsmaade til fremstilling heraf og antitumormiddel |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4650799A (da) |
| EP (1) | EP0140327B1 (da) |
| JP (1) | JPS6097963A (da) |
| AU (1) | AU571273B2 (da) |
| CA (1) | CA1244430A (da) |
| DE (1) | DE3482322D1 (da) |
| DK (1) | DK162639C (da) |
| ES (1) | ES537206A0 (da) |
| NO (1) | NO170682C (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0674251B2 (ja) * | 1986-02-07 | 1994-09-21 | 全薬工業株式▲会▼社 | ビス−ジオキソピペラジン誘導体 |
| DK0491053T3 (da) * | 1990-07-04 | 1996-03-11 | Zenyaku Kogyo Kk | Vandopløselige bis-dioxopiperazinderivater med antitumoregenskaber |
| AU2010266040B2 (en) * | 2009-06-25 | 2015-01-15 | Alkermes Pharma Ireland Limited | Prodrugs of NH-acidic compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL273691A (da) * | 1961-01-19 | 1900-01-01 | ||
| GB1234935A (en) * | 1967-07-03 | 1971-06-09 | Nat Res Dev | Piperazine derivatives |
| GB1236947A (en) * | 1968-08-15 | 1971-06-23 | Ici Ltd | Process for the preparation of piperazine derivatives |
| DE2511891A1 (de) * | 1975-03-19 | 1976-10-07 | Gruenenthal Chemie | Neue derivate des 2,6-dioxopiperazins, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel sowie verfahren zu deren herstellung |
| CH635828A5 (de) * | 1978-08-30 | 1983-04-29 | Ciba Geigy Ag | N-substituierte imide und bisimide. |
| US4404381A (en) * | 1981-06-19 | 1983-09-13 | The Dow Chemical Company | Novel 3,5-diketo-piperazinyl compounds containing epoxide substituted imides |
| US4536564A (en) * | 1983-12-09 | 1985-08-20 | The Dow Chemical Company | Polyamide from bis-carboxy containing 3,5,3',5'-tetraoxo-1,2-dipiperazine compound and diamine |
-
1983
- 1983-10-31 JP JP58204448A patent/JPS6097963A/ja active Granted
-
1984
- 1984-10-16 DK DK493384A patent/DK162639C/da not_active IP Right Cessation
- 1984-10-17 AU AU34416/84A patent/AU571273B2/en not_active Ceased
- 1984-10-19 NO NO844183A patent/NO170682C/no not_active IP Right Cessation
- 1984-10-23 DE DE8484112763T patent/DE3482322D1/de not_active Expired - Fee Related
- 1984-10-23 EP EP84112763A patent/EP0140327B1/en not_active Expired - Lifetime
- 1984-10-25 US US06/664,700 patent/US4650799A/en not_active Expired - Lifetime
- 1984-10-30 CA CA000466567A patent/CA1244430A/en not_active Expired
- 1984-10-30 ES ES537206A patent/ES537206A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0140327B1 (en) | 1990-05-23 |
| NO844183L (no) | 1985-05-02 |
| US4650799A (en) | 1987-03-17 |
| EP0140327A2 (en) | 1985-05-08 |
| ES8507513A1 (es) | 1985-09-01 |
| CA1244430A (en) | 1988-11-08 |
| JPS6334153B2 (da) | 1988-07-08 |
| DE3482322D1 (de) | 1990-06-28 |
| AU3441684A (en) | 1985-05-09 |
| DK493384D0 (da) | 1984-10-16 |
| AU571273B2 (en) | 1988-04-14 |
| JPS6097963A (ja) | 1985-05-31 |
| DK493384A (da) | 1985-05-01 |
| NO170682C (no) | 1992-11-18 |
| DK162639B (da) | 1991-11-25 |
| EP0140327A3 (en) | 1986-07-23 |
| NO170682B (no) | 1992-08-10 |
| ES537206A0 (es) | 1985-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |