DK1621207T3 - Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors - Google Patents

Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors

Info

Publication number: DK1621207T3
Authority: DK; Denmark
Prior art keywords: defibrotide; csf; activating; mixture; haematopoietic progenitors
Prior art date: 2000-04-18

Application number

DK05108424.2T

Other languages

English (en)

Inventor

Laura Ferro

Roberto Porta

Massimo Iacobelli

Alessandro Massimo Gianni

Carmelo Carlo Stella

Original Assignee

Gentium Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-18

Filing date

2001-04-10

Publication date

2010-02-01

2001-04-10 Application filed by Gentium Spa filed Critical Gentium Spa

2010-02-01 Application granted granted Critical

2010-02-01 Publication of DK1621207T3 publication Critical patent/DK1621207T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Hematology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK05108424.2T 2000-04-18 2001-04-10 Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors DK1621207T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00830293A EP1147777A1 (en)	2000-04-18	2000-04-18	Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
EP01931582A EP1276497B1 (en)	2000-04-18	2001-04-10	Mixture of defibrotide and g-csf and its use for activating haematopoietic progenitors

Publications (1)

Publication Number	Publication Date
DK1621207T3 true DK1621207T3 (da)	2010-02-01

Family

ID=8175292

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK01931582T DK1276497T3 (da)	2000-04-18	2001-04-10	Blanding af defibrotid og G-CSF og anvendelse heraf til aktivering af hæmatopoietiske progenitorceller
DK05108424.2T DK1621207T3 (da)	2000-04-18	2001-04-10	Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK01931582T DK1276497T3 (da)	2000-04-18	2001-04-10	Blanding af defibrotid og G-CSF og anvendelse heraf til aktivering af hæmatopoietiske progenitorceller

Country Status (31)

Country	Link
US (1)	US20040131588A1 (da)
EP (3)	EP1147777A1 (da)
JP (1)	JP5205668B2 (da)
KR (1)	KR100849491B1 (da)
CN (1)	CN1183962C (da)
AT (2)	ATE310532T1 (da)
AU (2)	AU5832201A (da)
BG (1)	BG107203A (da)
CA (1)	CA2406179C (da)
CY (1)	CY1104971T1 (da)
CZ (1)	CZ20023426A3 (da)
DE (2)	DE60115222T2 (da)
DK (2)	DK1276497T3 (da)
EE (1)	EE200200596A (da)
ES (2)	ES2252227T3 (da)
HR (1)	HRP20020835A2 (da)
HU (1)	HUP0300560A3 (da)
IL (1)	IL152328A (da)
IS (1)	IS2171B (da)
MX (1)	MXPA02010346A (da)
NO (1)	NO20024988L (da)
NZ (1)	NZ522016A (da)
PL (1)	PL358100A1 (da)
PT (1)	PT1621207E (da)
RO (1)	RO121006B1 (da)
RU (1)	RU2248216C2 (da)
SI (1)	SI21079B (da)
SK (1)	SK14892002A3 (da)
UA (1)	UA73566C2 (da)
WO (1)	WO2001078761A2 (da)
ZA (1)	ZA200208413B (da)

Families Citing this family (11)

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Publication number	Priority date	Publication date	Assignee	Title
US8771663B2 (en)	2000-04-18	2014-07-08	Gentium Spa	Formulation having mobilising activity
US7417026B2 (en)	2003-08-13	2008-08-26	Children's Hospital Medical Center	Mobilization of hematopoietic cells
US20050069553A1 (en)	2003-08-13	2005-03-31	Yi Zheng	Chimeric peptides for the regulation of GTPases
EP2103689A1 (en) *	2008-03-19	2009-09-23	Gentium S.p.A.	Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
RU2376985C1 (ru) *	2008-07-17	2009-12-27	Владислав Николаевич Ласкавый	Средство для активации стволовых клеток
AU2010363814B2 (en)	2010-11-12	2016-05-19	Gentium S.R.L.	Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD).
CA2874960C (en)	2012-06-22	2021-05-18	Gentium S.P.A.	Euglobulin-based method for determining the biological activity of defibrotide
EP3026122A1 (en)	2014-11-27	2016-06-01	Gentium S.p.A.	Cellular-based method for determining the potency of defibrotide
CN106567694A (zh) *	2016-11-14	2017-04-19	北京国泰通源技术有限公司	智能控水短节
CN110352246B (zh) *	2018-01-12	2024-08-20	赛尔美格公司	产生细胞囊和细胞囊管的方法
KR102749256B1 (ko)	2019-11-13	2025-01-03	후지필름 가부시키가이샤	가식 필름, 성형물, 및 전자 디바이스

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DE2154279A1 (de) *	1970-11-03	1972-05-25	Crinos Industria Farmaco	Medikamente für das fibrinolytische System
IT1206341B (it)	1984-02-16	1989-04-14	Crinos Industria Farmaco	Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
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IT1190313B (it)	1986-04-17	1988-02-16	Crinos Industria Farmaco	Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
US5223609A (en)	1986-04-17	1993-06-29	Crinos Industria Farmacobiologica S.P.A.	Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
IT1223322B (it) *	1987-10-23	1990-09-19	Crinos Industria Farmaco	Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
JP2907447B2 (ja) *	1988-08-24	1999-06-21	中外製薬株式会社	抗血栓剤
IT1231509B (it) *	1989-09-07	1991-12-07	Crinos Industria Farmaco	Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US5199942A (en) *	1991-06-07	1993-04-06	Immunex Corporation	Method for improving autologous transplantation
US5977083A (en) *	1991-08-21	1999-11-02	Burcoglu; Arsinur	Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
JP3021906B2 (ja) *	1992-01-28	2000-03-15	松下電器産業株式会社	電動調理機
JPH08127539A (ja) *	1994-10-31	1996-05-21	Ajinomoto Co Inc	ヒトｉｌ−１１を含有する末梢血幹細胞増加剤
AU3994095A (en) *	1994-11-30	1996-06-19	Chugai Seiyaku Kabushiki Kaisha	Thrombocytotic factor
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2000
- 2000-04-18 EP EP00830293A patent/EP1147777A1/en not_active Withdrawn
2001
- 2001-04-10 EP EP05108424A patent/EP1621207B1/en not_active Expired - Lifetime
- 2001-04-10 SK SK1489-2002A patent/SK14892002A3/sk unknown
- 2001-04-10 AT AT01931582T patent/ATE310532T1/de active
- 2001-04-10 DK DK01931582T patent/DK1276497T3/da active
- 2001-04-10 EP EP01931582A patent/EP1276497B1/en not_active Expired - Lifetime
- 2001-04-10 CA CA2406179A patent/CA2406179C/en not_active Expired - Fee Related
- 2001-04-10 IL IL152328A patent/IL152328A/en active IP Right Grant
- 2001-04-10 DK DK05108424.2T patent/DK1621207T3/da active
- 2001-04-10 NZ NZ522016A patent/NZ522016A/en unknown
- 2001-04-10 PL PL01358100A patent/PL358100A1/xx not_active Application Discontinuation
- 2001-04-10 HU HU0300560A patent/HUP0300560A3/hu unknown
- 2001-04-10 DE DE60115222T patent/DE60115222T2/de not_active Expired - Lifetime
- 2001-04-10 ES ES01931582T patent/ES2252227T3/es not_active Expired - Lifetime
- 2001-04-10 AT AT05108424T patent/ATE443524T1/de active
- 2001-04-10 RO ROA200201305A patent/RO121006B1/ro unknown
- 2001-04-10 MX MXPA02010346A patent/MXPA02010346A/es active IP Right Grant
- 2001-04-10 AU AU5832201A patent/AU5832201A/xx active Pending
- 2001-04-10 US US10/432,741 patent/US20040131588A1/en not_active Abandoned
- 2001-04-10 ES ES05108424T patent/ES2335776T3/es not_active Expired - Lifetime
- 2001-04-10 EE EEP200200596A patent/EE200200596A/xx unknown
- 2001-04-10 KR KR1020027013967A patent/KR100849491B1/ko not_active Expired - Fee Related
- 2001-04-10 DE DE60140015T patent/DE60140015D1/de not_active Expired - Lifetime
- 2001-04-10 JP JP2001576061A patent/JP5205668B2/ja not_active Expired - Fee Related
- 2001-04-10 CZ CZ20023426A patent/CZ20023426A3/cs unknown
- 2001-04-10 CN CNB018082025A patent/CN1183962C/zh not_active Expired - Fee Related
- 2001-04-10 PT PT05108424T patent/PT1621207E/pt unknown
- 2001-04-10 WO PCT/EP2001/004105 patent/WO2001078761A2/en active IP Right Grant
- 2001-04-10 SI SI200120022A patent/SI21079B/sl not_active IP Right Cessation
- 2001-04-10 AU AU2001258322A patent/AU2001258322B2/en not_active Ceased
- 2001-04-10 RU RU2002130719/15A patent/RU2248216C2/ru not_active IP Right Cessation
- 2001-10-04 UA UA2002119177A patent/UA73566C2/uk unknown
2002
- 2002-10-14 IS IS6581A patent/IS2171B/is unknown
- 2002-10-16 NO NO20024988A patent/NO20024988L/no not_active Application Discontinuation
- 2002-10-17 BG BG107203A patent/BG107203A/bg unknown
- 2002-10-17 ZA ZA200208413A patent/ZA200208413B/en unknown
- 2002-10-18 HR HR20020835A patent/HRP20020835A2/xx not_active Application Discontinuation
2006
- 2006-02-08 CY CY20061100179T patent/CY1104971T1/el unknown

Also Published As

Publication number	Publication date
EP1147777A1 (en)	2001-10-24
JP5205668B2 (ja)	2013-06-05
CA2406179A1 (en)	2001-10-25
DE60115222D1 (de)	2005-12-29
WO2001078761A3 (en)	2002-01-24
DE60140015D1 (de)	2009-11-05
AU5832201A (en)	2001-10-30
PT1621207E (pt)	2009-12-28
SK14892002A3 (sk)	2003-06-03
KR100849491B1 (ko)	2008-07-31
EP1276497A2 (en)	2003-01-22
MXPA02010346A (es)	2004-09-06
RU2248216C2 (ru)	2005-03-20
CA2406179C (en)	2012-03-27
ATE443524T1 (de)	2009-10-15
ZA200208413B (en)	2003-10-17
WO2001078761A2 (en)	2001-10-25
AU2001258322B2 (en)	2006-03-16
RU2002130719A (ru)	2004-03-27
IS2171B (is)	2006-11-15
HUP0300560A2 (hu)	2003-06-28
BG107203A (bg)	2003-05-30
IL152328A (en)	2009-12-24
EP1276497B1 (en)	2005-11-23
JP2004500437A (ja)	2004-01-08
EP1621207A2 (en)	2006-02-01
NO20024988L (no)	2002-12-02
SI21079A (sl)	2003-06-30
NZ522016A (en)	2004-10-29
HUP0300560A3 (en)	2005-07-28
CN1434719A (zh)	2003-08-06
EP1621207A3 (en)	2006-11-22
CN1183962C (zh)	2005-01-12
HRP20020835A2 (en)	2005-10-31
KR20030010603A (ko)	2003-02-05
CY1104971T1 (el)	2010-03-03
ES2335776T3 (es)	2010-04-05
ES2252227T3 (es)	2006-05-16
RO121006B1 (ro)	2006-11-30
DK1276497T3 (da)	2006-03-27
PL358100A1 (en)	2004-08-09
NO20024988D0 (no)	2002-10-16
SI21079B (sl)	2006-08-31
IL152328A0 (en)	2003-05-29
EP1621207B1 (en)	2009-09-23
IS6581A (is)	2002-10-14
US20040131588A1 (en)	2004-07-08
CZ20023426A3 (cs)	2003-05-14
EE200200596A (et)	2004-04-15
ATE310532T1 (de)	2005-12-15
UA73566C2 (en)	2005-08-15
DE60115222T2 (de)	2006-08-10

Publication	Publication Date	Title
AU2001269688A1 (en)	2002-01-14	Combination containing an antifolate and methylmalonic acid lowering agent
ES2160577T3 (es)	2001-11-16	Nuevos esteres de aminoalcoholes biciclicos y triciclicos, su preparacion y su utilizacion en medicamentos.
TW200505900A (en)	2005-02-16	Muscarinic agonists
DK1621207T3 (da)	2010-02-01	Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors
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EP1023901A4 (en)	2004-10-27	MEDICINES FOR HEPATITIS C AND THE USE THEREOF
ES2181915T3 (es)	2003-03-01	Ctla-8 en combinacionpn con g-csf y il-6, y uso de ctla-8 para tratar infecciones.
TR200101336T2 (tr)	2001-11-21	Bir-beta-agonisti ile başka bir antidiyabetik madde içeren kombinasyonlar
YU79802A (sh)	2005-11-28	Formulacija sa aktivnošću mobilizacije
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Kim et al.	1997	Synergistic Cooperation Between Human Chorionic Gonadotropin and rIFN-Υ for Induction of Nitric Oxide Synthesis
DE69829982D1 (de)	2005-08-18	Mittel und therapieverfahren für auf igf-i ansprechende erkrankungen
ITGE930069A1 (it)	1995-01-28	Dispositivo ausiliario automatico per siringhe preriempite per facilitare l'introduzione dell'ago nel corpo del paziente.