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DK1599433T3 - Fremgangsmåde til fremstilling af de enantiomere former af cis-konfigurerede 1,3-cyclohexandiolderivater - Google Patents

Fremgangsmåde til fremstilling af de enantiomere former af cis-konfigurerede 1,3-cyclohexandiolderivater

Info

Publication number
DK1599433T3
DK1599433T3 DK04712518T DK04712518T DK1599433T3 DK 1599433 T3 DK1599433 T3 DK 1599433T3 DK 04712518 T DK04712518 T DK 04712518T DK 04712518 T DK04712518 T DK 04712518T DK 1599433 T3 DK1599433 T3 DK 1599433T3
Authority
DK
Denmark
Prior art keywords
cis
preparing
enantiomeric forms
cyclohexanediol derivatives
cyclohexanediol
Prior art date
Application number
DK04712518T
Other languages
English (en)
Inventor
Wolfgang Holla
Stefanie Keil
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1599433T3 publication Critical patent/DK1599433T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK04712518T 2003-02-27 2004-02-19 Fremgangsmåde til fremstilling af de enantiomere former af cis-konfigurerede 1,3-cyclohexandiolderivater DK1599433T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10308350A DE10308350B4 (de) 2003-02-27 2003-02-27 Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
PCT/EP2004/001580 WO2004076390A1 (de) 2003-02-27 2004-02-19 Verfahren zur herstellung der enantiomeren formen von cis-konfigurierten 1,3-cyclohexandiol-derivaten

Publications (1)

Publication Number Publication Date
DK1599433T3 true DK1599433T3 (da) 2007-04-16

Family

ID=32863920

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04712518T DK1599433T3 (da) 2003-02-27 2004-02-19 Fremgangsmåde til fremstilling af de enantiomere former af cis-konfigurerede 1,3-cyclohexandiolderivater

Country Status (24)

Country Link
EP (1) EP1599433B1 (da)
JP (1) JP2006519001A (da)
KR (1) KR20050107469A (da)
CN (1) CN100572348C (da)
AR (1) AR044501A1 (da)
AT (1) ATE347543T1 (da)
AU (1) AU2004215674B2 (da)
BR (1) BRPI0407844A (da)
CA (1) CA2516623A1 (da)
CO (1) CO5690547A2 (da)
CY (1) CY1106454T1 (da)
DE (2) DE10308350B4 (da)
DK (1) DK1599433T3 (da)
ES (1) ES2278305T3 (da)
IL (1) IL170310A (da)
MX (1) MXPA05009053A (da)
NO (1) NO20054456L (da)
NZ (1) NZ542025A (da)
PL (1) PL377812A1 (da)
PT (1) PT1599433E (da)
RU (1) RU2372319C2 (da)
TW (1) TWI331138B (da)
WO (1) WO2004076390A1 (da)
ZA (1) ZA200505760B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten
DE102004040736B4 (de) * 2004-08-23 2007-01-11 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Diarylcycloalkylderivaten
CN101381302B (zh) * 2007-09-07 2013-04-03 上海睿智化学研究有限公司 2-溴甲基-6-甲基苯甲酰氯/溴的制备方法
EP2298755A4 (en) 2008-05-21 2012-12-05 Taisho Pharmaceutical Co Ltd PROCESS FOR PRODUCING BICYCLO [3.1.0] HEXANE DERIVATIVE WITH ENZYME
JP7185633B2 (ja) 2017-02-17 2022-12-07 トレベナ・インコーポレイテッド 7員アザ複素環を含有するデルタ-オピオイド受容体調節化合物、その使用方法及び製造方法
WO2023070605A1 (en) * 2021-10-29 2023-05-04 Trevena, Inc. Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
CN114891838B (zh) * 2022-04-29 2023-09-08 株洲壹诺生物技术有限公司 盐酸多佐胺中间体(s)-3-(2-噻吩硫基)-丁酸的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU74701A (sh) * 1999-04-28 2005-07-19 Aventis Pharma Deutschland Gmbh. Derivati tri-aril kiseline kao ligandi ppar receptora
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
CN1255103C (zh) * 2001-08-31 2006-05-10 塞诺菲-安万特德国有限公司 二芳基环烷基衍生物、其制备方法及其作为ppar激活剂的应用

Also Published As

Publication number Publication date
CO5690547A2 (es) 2006-10-31
AU2004215674B2 (en) 2010-02-04
DE502004002234D1 (de) 2007-01-18
KR20050107469A (ko) 2005-11-11
BRPI0407844A (pt) 2006-02-14
IL170310A (en) 2010-06-16
NO20054456L (no) 2005-09-26
EP1599433A1 (de) 2005-11-30
EP1599433B1 (de) 2006-12-06
CY1106454T1 (el) 2011-10-12
PT1599433E (pt) 2007-02-28
AR044501A1 (es) 2005-09-14
NZ542025A (en) 2009-03-31
DE10308350A1 (de) 2004-09-16
RU2005129993A (ru) 2006-01-27
CN1753855A (zh) 2006-03-29
CA2516623A1 (en) 2004-09-10
HK1088889A1 (zh) 2006-11-17
ES2278305T3 (es) 2007-08-01
PL377812A1 (pl) 2006-02-20
JP2006519001A (ja) 2006-08-24
TWI331138B (en) 2010-10-01
RU2372319C2 (ru) 2009-11-10
MXPA05009053A (es) 2005-10-19
ATE347543T1 (de) 2006-12-15
WO2004076390A1 (de) 2004-09-10
AU2004215674A1 (en) 2004-09-10
DE10308350B4 (de) 2006-06-01
ZA200505760B (en) 2006-05-31
CN100572348C (zh) 2009-12-23
TW200508392A (en) 2005-03-01

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