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DK1587504T3 - Process for the preparation of a thin film comprising heat sensitive active substances - Google Patents

Process for the preparation of a thin film comprising heat sensitive active substances

Info

Publication number
DK1587504T3
DK1587504T3 DK04707004.0T DK04707004T DK1587504T3 DK 1587504 T3 DK1587504 T3 DK 1587504T3 DK 04707004 T DK04707004 T DK 04707004T DK 1587504 T3 DK1587504 T3 DK 1587504T3
Authority
DK
Denmark
Prior art keywords
preparation
thin film
active substances
heat sensitive
sensitive active
Prior art date
Application number
DK04707004.0T
Other languages
Danish (da)
Inventor
Robert K Yang
Richard C Fuisz
Gary L Myers
Joseph M Fuisz
Original Assignee
Monosolrx Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monosolrx Llc filed Critical Monosolrx Llc
Application granted granted Critical
Publication of DK1587504T3 publication Critical patent/DK1587504T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B13/00—Machines and apparatus for drying fabrics, fibres, yarns, or other materials in long lengths, with progressive movement
    • F26B13/10—Arrangements for feeding, heating or supporting materials; Controlling movement, tension or position of materials
    • F26B13/101—Supporting materials without tension, e.g. on or between foraminous belts
    • F26B13/104—Supporting materials without tension, e.g. on or between foraminous belts supported by fluid jets only; Fluid blowing arrangements for flotation dryers, e.g. coanda nozzles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Textile Engineering (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
DK04707004.0T 2003-01-30 2004-01-30 Process for the preparation of a thin film comprising heat sensitive active substances DK1587504T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44374103P 2003-01-30 2003-01-30
PCT/US2004/002602 WO2004066986A1 (en) 2003-01-30 2004-01-30 Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom

Publications (1)

Publication Number Publication Date
DK1587504T3 true DK1587504T3 (en) 2012-07-02

Family

ID=32825368

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04707004.0T DK1587504T3 (en) 2003-01-30 2004-01-30 Process for the preparation of a thin film comprising heat sensitive active substances

Country Status (7)

Country Link
EP (2) EP2428206A1 (en)
JP (4) JP5165888B2 (en)
CN (1) CN100356908C (en)
AT (1) ATE553746T1 (en)
CA (1) CA2514897C (en)
DK (1) DK1587504T3 (en)
WO (1) WO2004066986A1 (en)

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JP4795962B2 (en) * 2003-05-28 2011-10-19 モノソル・アールエックス・エルエルシー Polyethylene oxide film and drug delivery system comprising the same
US9044049B2 (en) 2005-04-29 2015-06-02 Philip Morris Usa Inc. Tobacco pouch product
EP1909603B1 (en) 2005-04-29 2009-10-21 Philip Morris Products S.A. Tobacco pouch product
JP4919643B2 (en) * 2005-09-30 2012-04-18 松谷化学工業株式会社 Soluble film
US8685478B2 (en) 2005-11-21 2014-04-01 Philip Morris Usa Inc. Flavor pouch
CN1851462B (en) * 2006-05-18 2010-12-08 浙江大学 A kind of preparation method of cellulose adsorption and transfer film
CN100463674C (en) * 2006-12-22 2009-02-25 江苏奥赛康药业有限公司 Oral cavity quick dissolved film containing civeran, and method for preparing the same
US8616221B2 (en) 2007-02-28 2013-12-31 Philip Morris Usa Inc. Oral pouch product with flavored wrapper
US9888712B2 (en) 2007-06-08 2018-02-13 Philip Morris Usa Inc. Oral pouch products including a liner and tobacco beads
WO2009010884A2 (en) 2007-07-16 2009-01-22 Philip Morris Products S.A. Tobacco-free oral flavor delivery pouch product
WO2009010876A2 (en) 2007-07-16 2009-01-22 Philip Morris Products S.A. Oral pouch product having soft edge and method of making
WO2009010875A2 (en) 2007-07-16 2009-01-22 Philip Morris Products S.A. Oral delivery pouch product with coated seam
US8282954B2 (en) * 2008-12-15 2012-10-09 Monosol Rx, Llc Method for manufacturing edible film
US8377215B2 (en) 2008-12-18 2013-02-19 Philip Morris Usa Inc. Moist botanical pouch processing
US9027567B2 (en) 2008-12-30 2015-05-12 Philip Morris Usa Inc. Oral pouch product with multi-layered pouch wrapper
WO2010086989A1 (en) 2009-01-29 2010-08-05 日東電工株式会社 Intraoral film-shaped base and preparation
US8863755B2 (en) 2009-02-27 2014-10-21 Philip Morris Usa Inc. Controlled flavor release tobacco pouch products and methods of making
EP2952191B1 (en) 2009-06-12 2018-08-22 Sunovion Pharmaceuticals Inc. Sublingual apomorphine
US8747562B2 (en) 2009-10-09 2014-06-10 Philip Morris Usa Inc. Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
MY150626A (en) 2009-10-30 2014-02-07 Ix Biopharma Ltd Fast dissolving solid dosage form
BR112012016271A2 (en) * 2009-12-31 2016-05-24 Bostik Inc process for packaging sticky polyester resins
JP2011207847A (en) 2010-03-30 2011-10-20 Nitto Denko Corp Film-form preparation and method for producing the same
JP5751868B2 (en) 2010-03-30 2015-07-22 日東電工株式会社 Film-form preparation and method for producing the same
JP6093693B2 (en) 2010-04-12 2017-03-08 アルトリア クライアント サービシーズ エルエルシー Bag product with improved seal and method of manufacturing
EP2651357B1 (en) 2010-12-16 2020-04-01 Sunovion Pharmaceuticals Inc. Sublingual films
JP5841433B2 (en) 2012-01-11 2016-01-13 日東電工株式会社 Intraoral film-form base and preparation
EP2857005A1 (en) 2013-10-04 2015-04-08 Hexal AG Method for manufacturing an ingestible film, apparatus for manufacturing an ingestible film, ingestible film and pharmaceutical dosage form comprising the same
JP6574556B2 (en) 2014-08-27 2019-09-11 日東電工株式会社 Intraoral film-form base and preparation
JP7211706B2 (en) 2015-04-21 2023-01-24 サノヴィオン ファーマシュティカルズ インコーポレーテッド Method for treating Parkinson's disease by administering apomorphine to oral mucosa
CN117153285B (en) * 2023-10-30 2024-01-23 江苏辰星药业股份有限公司 Method and system for analyzing specific components of plant empty capsules

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JPS4716039B1 (en) * 1967-12-11 1972-05-12
US4136145A (en) 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
IN142428B (en) * 1974-07-05 1977-07-09 Schering Ag
US4631837A (en) 1985-05-31 1986-12-30 Magoon Richard E Method and apparatus for drying fruit pulp and the like
US4849246A (en) * 1985-10-09 1989-07-18 Wolfgang Schmidt Process for producing an administration or dosage form for drugs, reagents or other active ingredients
DE3630603A1 (en) * 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh PHARMACEUTICAL AND DOSAGE FORM FOR MEDICINAL ACTIVE SUBSTANCES, REAGENTS OR THE LIKE, AND METHOD FOR THE PRODUCTION THEREOF
DE4018247A1 (en) * 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts MANUFACTURING METHOD FOR QUICK-DISINFITTING FILM-SHAPED PHARMACEUTICAL FORMS
IT1249315B (en) * 1991-05-23 1995-02-22 Euroresearch Srl NON-POROUS COLLAGEN PLATE FOR THERAPEUTIC USE, METHOD AND EQUIPMENT TO OBTAIN IT
US5393528A (en) * 1992-05-07 1995-02-28 Staab; Robert J. Dissolvable device for contraception or delivery of medication
DE19646392A1 (en) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Preparation for use in the oral cavity with a layer containing pressure-sensitive adhesive, pharmaceuticals or cosmetics for dosed delivery
US20020127254A1 (en) * 1998-06-25 2002-09-12 Lavipharm Laboratories Inc. Devices for local and systemic delivery of active substance and methods of manufacturing thereof
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
EP1110546A1 (en) * 1999-12-23 2001-06-27 Johnson & Johnson Consumer Companies, Inc. Method of preparing a water soluble film
US6375981B1 (en) * 2000-06-01 2002-04-23 A. E. Staley Manufacturing Co. Modified starch as a replacement for gelatin in soft gel films and capsules
JP4883739B2 (en) * 2000-06-13 2012-02-22 日東電工株式会社 Water-dispersed adhesive sheet and method for producing the same
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EP1458367B2 (en) * 2001-10-12 2021-01-27 Aquestive Therapeutics, Inc. Uniform films for rapidly dissolving dosage form incorporating taste-masking compositions
ES2735512T3 (en) * 2001-10-12 2019-12-19 Aquestive Therapeutics Inc Thin film with uniform non-self-aggregating heterogeneity, process for its production and drug delivery systems made from it

Also Published As

Publication number Publication date
JP5723601B2 (en) 2015-05-27
EP2428206A1 (en) 2012-03-14
CA2514897C (en) 2012-08-28
CN1764443A (en) 2006-04-26
JP2013028635A (en) 2013-02-07
WO2004066986A1 (en) 2004-08-12
CA2514897A1 (en) 2004-08-12
JP2006516634A (en) 2006-07-06
EP1587504B1 (en) 2012-04-18
WO2004066986A9 (en) 2004-09-30
JP5165888B2 (en) 2013-03-21
JP2011068689A (en) 2011-04-07
JP2015098494A (en) 2015-05-28
CN100356908C (en) 2007-12-26
ATE553746T1 (en) 2012-05-15
JP6109865B2 (en) 2017-04-05
EP1587504A1 (en) 2005-10-26

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