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DK1574221T3 - Stabile, injicérbare diclofenacsammensætninger - Google Patents

Stabile, injicérbare diclofenacsammensætninger

Info

Publication number
DK1574221T3
DK1574221T3 DK04257437T DK04257437T DK1574221T3 DK 1574221 T3 DK1574221 T3 DK 1574221T3 DK 04257437 T DK04257437 T DK 04257437T DK 04257437 T DK04257437 T DK 04257437T DK 1574221 T3 DK1574221 T3 DK 1574221T3
Authority
DK
Denmark
Prior art keywords
diclofenac
cyclodextrin
stable
salt
pharmaceutically acceptable
Prior art date
Application number
DK04257437T
Other languages
Danish (da)
English (en)
Inventor
Lawrence John Penkler
Original Assignee
Shimoda Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34826259&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1574221(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shimoda Biotech Pty Ltd filed Critical Shimoda Biotech Pty Ltd
Application granted granted Critical
Publication of DK1574221T3 publication Critical patent/DK1574221T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK04257437T 2004-03-10 2004-11-30 Stabile, injicérbare diclofenacsammensætninger DK1574221T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55135104P 2004-03-10 2004-03-10

Publications (1)

Publication Number Publication Date
DK1574221T3 true DK1574221T3 (da) 2007-07-16

Family

ID=34826259

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07075004.7T DK1767219T3 (da) 2004-03-10 2004-11-30 Stabile injicerbare diclofenac-sammensætninger
DK04257437T DK1574221T3 (da) 2004-03-10 2004-11-30 Stabile, injicérbare diclofenacsammensætninger

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK07075004.7T DK1767219T3 (da) 2004-03-10 2004-11-30 Stabile injicerbare diclofenac-sammensætninger

Country Status (20)

Country Link
US (2) US20050238674A1 (es)
EP (2) EP1574221B1 (es)
JP (1) JP2007528384A (es)
KR (1) KR20070028331A (es)
AT (2) ATE364402T1 (es)
AU (1) AU2004317520B2 (es)
BR (1) BRPI0418474A (es)
CA (1) CA2555429C (es)
CY (1) CY1106824T1 (es)
DE (2) DE602004025151D1 (es)
DK (2) DK1767219T3 (es)
ES (2) ES2287658T3 (es)
HK (1) HK1079118A1 (es)
IL (1) IL177529A (es)
MX (1) MXPA06010336A (es)
PL (2) PL1574221T3 (es)
PT (2) PT1767219E (es)
SI (2) SI1574221T1 (es)
WO (2) WO2005092387A1 (es)
ZA (2) ZA200607631B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA93365C2 (ru) 2005-02-01 2011-02-10 Троикаа Фармасьютикалс Лтд Инъекционная форма диклофенака и его фармацевтически приемлемых солей (варианты) и способ его приготовления (варианты)
US20060205080A1 (en) * 2005-03-01 2006-09-14 David Frey Formulations for therapeutic viruses having enhanced storage stability
EP2004203A4 (en) 2006-03-28 2010-03-31 Javelin Pharmaceuticals Inc FORMULATIONS OF DICLOFENAC AND CYCLODEXTRIN BETA WITH LOW DOSAGE
CN101410012A (zh) * 2006-03-28 2009-04-15 杰佛林制药公司 低剂量的非甾体抗炎药和β-环糊精的制剂
AU2012209035B9 (en) * 2006-03-28 2014-05-22 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
CL2007003877A1 (es) 2007-12-28 2008-06-27 Univ De Concepcion Lab Androma Composicion farmaceutica que comprende un complejo de inclusion formado por disulfiram y una ciclodextrina; y su uso para el tratamiento de la dependencia de alcohol y cocaina.
US20100022652A1 (en) * 2008-07-28 2010-01-28 Tyco Healthcare Group Lp Antimicrobial and Anticoagulant Compositions and Methods
AU2010224866C1 (en) 2009-03-16 2015-01-15 Genmedica Therapeutics Sl Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders
US8466197B2 (en) 2010-12-14 2013-06-18 Genmedica Therapeutics Sl Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders
GB201021267D0 (en) * 2010-12-15 2011-01-26 Reckitt Benckiser Healthcare Int Ltd Novel pharmaceutical formulation
MX350463B (es) * 2011-07-20 2017-09-06 Hospira Inc Métodos de tratamiento del dolor.
WO2013020600A1 (en) * 2011-08-11 2013-02-14 Cross Sa Pharmaceutical composition comprising a drug containing at least one toxicophore function and n-acetyl-l-cysteine
KR101260636B1 (ko) 2012-11-29 2013-05-13 씨제이제일제당 (주) 안정화된 페메트렉시드 제제
US20140187635A1 (en) 2012-12-28 2014-07-03 Themis Medicare Limited Diclofenac compositions
US20140275261A1 (en) 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
KR101485243B1 (ko) 2013-05-08 2015-01-21 씨제이헬스케어 주식회사 안정화된 페메트렉시드 제제
US11110073B2 (en) 2017-03-24 2021-09-07 Cadila Healthcare Limited Storage stable aqueous injectable solution comprising diclofenac
EP4389147A3 (en) * 2017-08-09 2024-10-23 Dechra Veterinary Products, LLC Therapeutic formulations and uses thereof
US20220280463A1 (en) 2019-09-09 2022-09-08 Ftf Pharma Private Limited Pharmaceutical formulations comprising diclofenac
US11707443B2 (en) 2019-09-26 2023-07-25 Rk Pharma Inc. Storage stable aqueous parenteral solutions comprising diclofenac
CN110872942B (zh) * 2019-10-24 2021-09-28 中国石油化工股份有限公司 油藏注采耦合方式下不同作用力对采收率贡献的研究方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3446873A1 (de) * 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
US5389681A (en) * 1992-10-22 1995-02-14 Ciba-Geigy Corporation Parenteral solutions for diclofenac salts
IL111184A (en) * 1993-10-08 2000-08-13 Farmarc Nederland B V Of Cito Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
CA2201134A1 (en) * 1994-10-10 1996-04-18 Alfred Sallmann Ophthalmic and aural compositions containing diclofenac potassium
US5821237A (en) * 1995-06-07 1998-10-13 The Procter & Gamble Company Compositions for visually improving skin
AU5774796A (en) * 1995-06-13 1997-01-09 Dyer, Alison Margaret Pharmaceutical compositions containing lornoxicam and cyclod extrin
TW434023B (en) * 1995-09-18 2001-05-16 Novartis Ag Preserved ophthalmic composition
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
ATE274955T1 (de) * 1999-05-03 2004-09-15 Battelle Memorial Institute Arzneizusammensetzungen zur aerosolbildung und zu inhalationszwecken
EP1219304B1 (de) * 2000-12-28 2004-10-20 Fresenius Kabi Austria GmbH Stabile Infusionslösung von Diclofenac-Salzen, deren Herstellung und Verwendung
ATE326985T1 (de) * 2002-02-01 2006-06-15 Shimoda Biotech Pty Ltd Lyophilisierte pharmazeutische zusammensetzung von propofol
BR0307893A (pt) * 2002-02-22 2004-12-07 Pharmacia Corp Formulação oftálmica com sistema de goma

Also Published As

Publication number Publication date
EP1767219A2 (en) 2007-03-28
KR20070028331A (ko) 2007-03-12
SI1767219T1 (sl) 2010-03-31
CA2555429A1 (en) 2005-10-06
EP1767219A3 (en) 2007-04-25
ZA200805860B (en) 2009-05-27
ZA200607631B (en) 2008-10-29
BRPI0418474A (pt) 2007-06-19
US20050238674A1 (en) 2005-10-27
ATE364402T1 (de) 2007-07-15
HK1079118A1 (en) 2006-03-31
PT1767219E (pt) 2010-02-15
IL177529A (en) 2013-08-29
WO2005086763A2 (en) 2005-09-22
WO2005092387A1 (en) 2005-10-06
PL1574221T3 (pl) 2007-10-31
CY1106824T1 (el) 2012-05-23
EP1767219B1 (en) 2010-01-13
JP2007528384A (ja) 2007-10-11
EP1574221A1 (en) 2005-09-14
DE602004006952D1 (de) 2007-07-26
DK1767219T3 (da) 2010-05-10
SI1574221T1 (sl) 2007-10-31
ES2336034T3 (es) 2010-04-07
AU2004317520B2 (en) 2011-06-09
WO2005086763A3 (en) 2006-03-02
PT1574221E (pt) 2007-07-09
DE602004006952T2 (de) 2008-02-14
DE602004025151D1 (de) 2010-03-04
US20120142779A1 (en) 2012-06-07
IL177529A0 (en) 2006-12-10
PL1767219T3 (pl) 2010-06-30
EP1574221B1 (en) 2007-06-13
CA2555429C (en) 2010-05-18
ES2287658T3 (es) 2007-12-16
ATE454905T1 (de) 2010-01-15
MXPA06010336A (es) 2007-02-16
AU2004317520A1 (en) 2005-10-06

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