DK157013C - Analogifremgangsmaade til fremstilling af fluorholdige 1,4-dihydropyridiner eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af fluorholdige 1,4-dihydropyridiner eller farmaceutisk acceptable syreadditionssalte deraf

Info

Publication number: DK157013C
Authority: DK; Denmark
Prior art keywords: preparation; fluorous; dihydropyridines; analogue; acid addition
Prior art date: 1978-09-25

Application number

DK399079A

Other languages

Danish (da)

English (en)

Other versions

DK399079A (da

DK157013B (da

Inventor

Harald Horstmann

Friedrich Bossert

Arend Heise

Stanislav Kazda

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-09-25

Filing date

1979-09-24

Publication date

1990-03-26

1979-09-24 Application filed by Bayer Ag filed Critical Bayer Ag

1980-03-26 Publication of DK399079A publication Critical patent/DK399079A/da

1989-10-30 Publication of DK157013B publication Critical patent/DK157013B/da

1990-03-26 Application granted granted Critical

1990-03-26 Publication of DK157013C publication Critical patent/DK157013C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK399079A 1978-09-25 1979-09-24 Analogifremgangsmaade til fremstilling af fluorholdige 1,4-dihydropyridiner eller farmaceutisk acceptable syreadditionssalte deraf DK157013C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2841667		1978-09-25
DE19782841667 DE2841667A1 (de)	1978-09-25	1978-09-25	Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (3)

Publication Number	Publication Date
DK399079A DK399079A (da)	1980-03-26
DK157013B DK157013B (da)	1989-10-30
DK157013C true DK157013C (da)	1990-03-26

Family

ID=6050376

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK399079A DK157013C (da)	1978-09-25	1979-09-24	Analogifremgangsmaade til fremstilling af fluorholdige 1,4-dihydropyridiner eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (15)

Country	Link
US (1)	US4256749A (fi)
EP (1)	EP0009206B1 (fi)
JP (2)	JPS6016934B2 (fi)
AT (1)	ATE290T1 (fi)
CA (1)	CA1130291A (fi)
DE (2)	DE2841667A1 (fi)
DK (1)	DK157013C (fi)
ES (1)	ES484397A1 (fi)
FI (1)	FI70887C (fi)
GR (1)	GR74127B (fi)
HK (1)	HK15184A (fi)
HU (1)	HU178449B (fi)
IE (1)	IE49462B1 (fi)
IL (1)	IL58299A (fi)
SG (1)	SG38783G (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2508446B1 (fr) *	1981-06-25	1986-05-02	Rhone Poulenc Agrochimie	Herbicides a fonctions amide et ester derives de la pyridine ainsi que leur procede de preparation et leur application
DE3130041A1 (de) *	1981-07-30	1983-02-17	Bayer Ag, 5090 Leverkusen	Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
JPS5897333U (ja) *	1981-12-24	1983-07-02	株式会社昭和製作所	油圧緩衝器の減衰力調整機構
JPS5897332U (ja) *	1981-12-24	1983-07-02	株式会社昭和製作所	油圧緩衝器の減衰力調整機構
DE3312283A1 (de) *	1983-04-05	1984-10-18	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3316510A1 (de) *	1983-05-06	1984-11-08	Bayer Ag	Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
US4677101A (en) *	1983-09-26	1987-06-30	Merck & Co., Inc.	Substituted dihydroazepines useful as calcium channel blockers
IE57810B1 (en) *	1984-03-27	1993-04-21	Delagrange Lab	1,4-dihydropyridine derivatives,their preparation and their use
EP0169009A3 (en) *	1984-07-17	1988-08-31	FISONS plc	Novel dihydropyridine derivatives and their production, formulation and use as pharmaceuticals
DE3544211A1 (de) *	1985-12-13	1987-06-19	Bayer Ag	Neue, fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS62292757A (ja) *	1986-06-12	1987-12-19	Taisho Pharmaceut Co Ltd	１，４−ジヒドロピリジン誘導体
US4868181A (en) *	1986-08-04	1989-09-19	E. I. Du Pont De Nemours And Company	1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
JPS63160458U (fi) *	1987-04-09	1988-10-20
US5177211A (en) *	1988-01-21	1993-01-05	Alter, S.A.	4-alkyl-1,4-dihydropyridines with PAF-antagonist activity
US5216172A (en) *	1988-02-24	1993-06-01	Ajinomoto Co., Inc.	1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
EP0330470A3 (en) *	1988-02-24	1992-01-02	Ajinomoto Co., Inc.	1,4-dihydropyridine derivatives useful against tumour cells
DE3833893A1 (de) *	1988-10-05	1990-04-12	Bayer Ag	Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte
JP3040364U (ja) *	1996-07-23	1997-08-19	清秀中川	芳香含有物質の詰め替え可能な枕

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2117571C3 (de) *	1971-04-10	1979-10-11	Bayer Ag, 5090 Leverkusen	Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2117573C3 (de) *	1971-04-10	1978-07-27	Bayer Ag, 5090 Leverkusen	Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel
GB1409865A (en) *	1973-02-13	1975-10-15	Science Union & Cie	Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
DE2508181A1 (de) *	1975-02-26	1976-09-09	Bayer Ag	1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1552911A (en) *	1975-07-02	1979-09-19	Fujisawa Pharmaceutical Co	1,4 dihydropyridine derivatives and the preparation thereof

1978
- 1978-09-25 DE DE19782841667 patent/DE2841667A1/de not_active Withdrawn
1979
- 1979-09-10 US US06/074,048 patent/US4256749A/en not_active Expired - Lifetime
- 1979-09-12 EP EP79103411A patent/EP0009206B1/de not_active Expired
- 1979-09-12 AT AT79103411T patent/ATE290T1/de active
- 1979-09-12 DE DE7979103411T patent/DE2961012D1/de not_active Expired
- 1979-09-21 JP JP54120911A patent/JPS6016934B2/ja not_active Expired
- 1979-09-21 CA CA336,100A patent/CA1130291A/en not_active Expired
- 1979-09-21 FI FI792939A patent/FI70887C/fi not_active IP Right Cessation
- 1979-09-21 IL IL58299A patent/IL58299A/xx unknown
- 1979-09-24 ES ES484397A patent/ES484397A1/es not_active Expired
- 1979-09-24 DK DK399079A patent/DK157013C/da not_active IP Right Cessation
- 1979-09-24 HU HU79BA3852A patent/HU178449B/hu not_active IP Right Cessation
- 1979-09-24 IE IE1802/79A patent/IE49462B1/en unknown
- 1979-09-24 GR GR60102A patent/GR74127B/el unknown
1983
- 1983-07-02 SG SG387/83A patent/SG38783G/en unknown
1984
- 1984-02-23 HK HK151/84A patent/HK15184A/xx unknown
- 1984-07-27 JP JP59155722A patent/JPS6069018A/ja active Granted

Also Published As

Publication number	Publication date
JPS6217972B2 (fi)	1987-04-21
EP0009206A3 (en)	1980-04-16
DE2961012D1 (en)	1981-12-24
CA1130291A (en)	1982-08-24
JPS6016934B2 (ja)	1985-04-30
FI792939A (fi)	1980-03-26
IL58299A0 (en)	1979-12-30
ES484397A1 (es)	1980-05-16
EP0009206B1 (de)	1981-10-14
JPS6069018A (ja)	1985-04-19
DK399079A (da)	1980-03-26
EP0009206A2 (de)	1980-04-02
GR74127B (fi)	1984-06-06
IE49462B1 (en)	1985-10-16
FI70887C (fi)	1986-10-27
FI70887B (fi)	1986-07-18
ATE290T1 (de)	1981-10-15
SG38783G (en)	1984-07-27
IL58299A (en)	1983-03-31
DK157013B (da)	1989-10-30
JPS5547657A (en)	1980-04-04
HK15184A (en)	1984-03-02
IE791802L (en)	1980-03-25
DE2841667A1 (de)	1980-04-10
US4256749A (en)	1981-03-17
HU178449B (en)	1982-05-28

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Legal Events

Date	Code	Title	Description
1991-05-27	PBP	Patent lapsed