DK1554374T3 - Fremgangsmåde til storskala T-lymfocytdyrkning i et homogent system - Google Patents
Fremgangsmåde til storskala T-lymfocytdyrkning i et homogent systemInfo
- Publication number
- DK1554374T3 DK1554374T3 DK03776860T DK03776860T DK1554374T3 DK 1554374 T3 DK1554374 T3 DK 1554374T3 DK 03776860 T DK03776860 T DK 03776860T DK 03776860 T DK03776860 T DK 03776860T DK 1554374 T3 DK1554374 T3 DK 1554374T3
- Authority
- DK
- Denmark
- Prior art keywords
- scale
- homogeneous system
- lymphocyte culture
- refers
- lymphocytic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 230000000527 lymphocytic effect Effects 0.000 abstract 2
- 230000003321 amplification Effects 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 238000011287 therapeutic dose Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002118A ITMI20022118A1 (it) | 2002-10-04 | 2002-10-04 | Procedimento per la coltura su larga scala di t-linfociti in un sistema omogeneo. |
| PCT/EP2003/011024 WO2004031370A1 (en) | 2002-10-04 | 2003-10-06 | Procedure for the large-scale t-lymphocytes culture in a homogeneous system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1554374T3 true DK1554374T3 (da) | 2007-05-07 |
Family
ID=32051228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03776860T DK1554374T3 (da) | 2002-10-04 | 2003-10-06 | Fremgangsmåde til storskala T-lymfocytdyrkning i et homogent system |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7678571B2 (de) |
| EP (1) | EP1554374B1 (de) |
| JP (1) | JP2006500936A (de) |
| CN (1) | CN100535107C (de) |
| AT (1) | ATE349513T1 (de) |
| AU (1) | AU2003286134B2 (de) |
| CA (1) | CA2500408C (de) |
| DE (1) | DE60310748T2 (de) |
| DK (1) | DK1554374T3 (de) |
| ES (1) | ES2279190T3 (de) |
| HK (1) | HK1076294A1 (de) |
| IT (1) | ITMI20022118A1 (de) |
| PT (1) | PT1554374E (de) |
| SI (1) | SI1554374T1 (de) |
| WO (1) | WO2004031370A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101302491B (zh) * | 2007-05-09 | 2011-09-14 | 王歈 | 高效扩增活化淋巴细胞的方法和培养系统 |
| SMT202400133T1 (it) * | 2016-10-26 | 2024-05-14 | Iovance Biotherapeutics Inc | Restimolazione di linfociti infiltranti il tumore crioconservati |
| US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
| CA3065532A1 (en) | 2017-06-05 | 2018-12-13 | Iovance Biotherapeutics, Inc. | Methods of using tumor infiltrating lymphocytes in double-refractory melanoma |
| US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
| CN111836887A (zh) | 2018-01-08 | 2020-10-27 | 艾欧凡斯生物治疗公司 | 产生富含肿瘤抗原特异性t细胞的til产品的方法 |
| MA52533A (fr) | 2018-04-27 | 2021-03-03 | Iovance Biotherapeutics Inc | Procédé en circuit fermé pour l'amplification et l'edition de gènes de lymphocytes d'infiltration des tumeurs et leurs utilisations en immunothérapie |
| CR20210295A (es) | 2018-11-05 | 2021-07-09 | Iovance Biotherapeutics Inc | Procesos para la producción de linfocitos infiltrantes de tumor y usos de estos en inmunoterapia |
| WO2023201369A1 (en) | 2022-04-15 | 2023-10-19 | Iovance Biotherapeutics, Inc. | Til expansion processes using specific cytokine combinations and/or akti treatment |
| CN115558641B (zh) * | 2022-11-14 | 2023-05-12 | 四川新生命干细胞科技股份有限公司 | 高纯度效应免疫细胞群及其培养方法、试剂组合物和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993025572A1 (en) * | 1992-06-05 | 1993-12-23 | Synergen, Inc. | T-cell monocyte inducing proteins (tmips) |
| DE69429657T2 (de) * | 1993-05-14 | 2002-09-12 | The Wistar Institute Of Anatomy And Biology, Philadelphia | Verwendung von modifizierten tall-104 zellen zur behandlung von krebs und viralen krankheiten |
| US5789147A (en) * | 1994-12-05 | 1998-08-04 | New York Blood Center, Inc. | Method for concentrating white cells from whole blood by adding a red cell sedimentation reagent to whole anticoagulated blood |
| US6022344A (en) * | 1997-12-04 | 2000-02-08 | Npbi International B.V. | Cryopreservation bag |
-
2002
- 2002-10-04 IT IT002118A patent/ITMI20022118A1/it unknown
-
2003
- 2003-10-06 AU AU2003286134A patent/AU2003286134B2/en not_active Expired
- 2003-10-06 WO PCT/EP2003/011024 patent/WO2004031370A1/en active IP Right Grant
- 2003-10-06 SI SI200330717T patent/SI1554374T1/sl unknown
- 2003-10-06 CA CA2500408A patent/CA2500408C/en not_active Expired - Lifetime
- 2003-10-06 JP JP2004540784A patent/JP2006500936A/ja active Pending
- 2003-10-06 DE DE60310748T patent/DE60310748T2/de not_active Expired - Lifetime
- 2003-10-06 ES ES03776860T patent/ES2279190T3/es not_active Expired - Lifetime
- 2003-10-06 US US10/530,108 patent/US7678571B2/en not_active Expired - Lifetime
- 2003-10-06 DK DK03776860T patent/DK1554374T3/da active
- 2003-10-06 EP EP03776860A patent/EP1554374B1/de not_active Expired - Lifetime
- 2003-10-06 PT PT03776860T patent/PT1554374E/pt unknown
- 2003-10-06 AT AT03776860T patent/ATE349513T1/de active
- 2003-10-06 CN CNB200380100954XA patent/CN100535107C/zh not_active Expired - Lifetime
-
2005
- 2005-12-01 HK HK05110954A patent/HK1076294A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SI1554374T1 (sl) | 2007-06-30 |
| AU2003286134B2 (en) | 2008-10-16 |
| HK1076294A1 (en) | 2006-01-13 |
| JP2006500936A (ja) | 2006-01-12 |
| US20060034802A1 (en) | 2006-02-16 |
| CA2500408A1 (en) | 2004-04-15 |
| CN1703506A (zh) | 2005-11-30 |
| DE60310748T2 (de) | 2007-10-11 |
| EP1554374A1 (de) | 2005-07-20 |
| ES2279190T3 (es) | 2007-08-16 |
| ITMI20022118A1 (it) | 2004-04-05 |
| WO2004031370A1 (en) | 2004-04-15 |
| CA2500408C (en) | 2015-02-17 |
| ATE349513T1 (de) | 2007-01-15 |
| PT1554374E (pt) | 2007-03-30 |
| US7678571B2 (en) | 2010-03-16 |
| DE60310748D1 (de) | 2007-02-08 |
| EP1554374B1 (de) | 2006-12-27 |
| CN100535107C (zh) | 2009-09-02 |
| AU2003286134A1 (en) | 2004-04-23 |
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