DK1529110T3 - Fremgangsmåde til blanding af store antal af heterologe gener - Google Patents
Fremgangsmåde til blanding af store antal af heterologe generInfo
- Publication number
- DK1529110T3 DK1529110T3 DK03787738.8T DK03787738T DK1529110T3 DK 1529110 T3 DK1529110 T3 DK 1529110T3 DK 03787738 T DK03787738 T DK 03787738T DK 1529110 T3 DK1529110 T3 DK 1529110T3
- Authority
- DK
- Denmark
- Prior art keywords
- heterologous genes
- methods
- cells
- large numbers
- evolution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Cell Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201173 | 2002-08-01 | ||
| DKPA200300787 | 2003-05-23 | ||
| PCT/DK2003/000521 WO2004016791A1 (en) | 2002-08-01 | 2003-08-01 | Methods of mixing large numbers of heterologous genes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1529110T3 true DK1529110T3 (da) | 2012-01-30 |
Family
ID=31889347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03787738.8T DK1529110T3 (da) | 2002-08-01 | 2003-08-01 | Fremgangsmåde til blanding af store antal af heterologe gener |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060252156A1 (da) |
| EP (1) | EP1529110B1 (da) |
| AT (1) | ATE527366T1 (da) |
| AU (1) | AU2003247270A1 (da) |
| DK (1) | DK1529110T3 (da) |
| WO (1) | WO2004016791A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8008459B2 (en) * | 2001-01-25 | 2011-08-30 | Evolva Sa | Concatemers of differentially expressed multiple genes |
| DK1356037T3 (da) * | 2001-01-25 | 2011-06-27 | Evolva Ltd | Bibliotek med en samling af celler |
| AU2003237662B2 (en) * | 2002-01-25 | 2008-04-24 | Evolva Ltd | Methods for multiple parameter screening and evolution of cells to produce small molecules with multiple functionalities |
| US20060130157A1 (en) | 2004-10-22 | 2006-06-15 | Kevin Wells | Ungulates with genetically modified immune systems |
| EA016258B1 (ru) | 2005-03-18 | 2012-03-30 | Микробиа, Инк. | Рекомбинантные грибы, продуцирующие каротиноиды, и способы их применения |
| JP2009544711A (ja) * | 2006-07-26 | 2009-12-17 | イントレクソン コーポレイション | 疾病の治療方法及び疾病治療用組成物 |
| EP2078092A2 (en) | 2006-09-28 | 2009-07-15 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| CN101343630B (zh) * | 2007-07-12 | 2012-11-07 | 中国科学院上海生命科学研究院 | 利用基因组改组技术改良多拉菌素生产菌的方法 |
| DK2348827T3 (da) | 2008-10-27 | 2015-07-20 | Revivicor Inc | Immunkompromitterede hovdyr |
| EP2571991A1 (en) | 2010-05-20 | 2013-03-27 | Evolva SA | Method of producing isoprenoid compounds in yeast |
| US20140308699A1 (en) | 2010-07-30 | 2014-10-16 | Glycode | Yeast artificial chromosome carrying the mammalian glycosylation pathway |
| CN107287185B (zh) * | 2017-07-22 | 2021-05-18 | 贵州省园艺研究所 | 马铃薯四倍体栽培种与二倍体野生种原生质体融合方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US25517A (en) * | 1859-09-20 | Improved method of making soap | ||
| US41333A (en) * | 1864-01-19 | Improvement in spinning-rollers | ||
| US19924A (en) * | 1858-04-13 | Improvement in seed-drills | ||
| US158860A (en) * | 1875-01-19 | Improvement in hame attachments | ||
| US5316922A (en) * | 1992-04-15 | 1994-05-31 | The United States Of America As Represented By Department Of Health And Human Services | Method for indentifying and expressing proteins that recognize and adhere to specific probes |
| US6268140B1 (en) * | 1994-02-03 | 2001-07-31 | Neugenesis | Combinatorial metabolic libraries |
| US6117679A (en) * | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US5837458A (en) * | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6165793A (en) * | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6309883B1 (en) * | 1994-02-17 | 2001-10-30 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| KR20040041639A (ko) * | 1995-04-24 | 2004-05-17 | 크로막솜 코포레이티드 | 새로운 대사 경로를 만들고 이를 스크리닝하는 방법 |
| US6030779A (en) * | 1995-07-18 | 2000-02-29 | Diversa Corporation | Screening for novel bioactivities |
| US6057103A (en) * | 1995-07-18 | 2000-05-02 | Diversa Corporation | Screening for novel bioactivities |
| US6004788A (en) * | 1995-07-18 | 1999-12-21 | Diversa Corporation | Enzyme kits and libraries |
| US5958672A (en) * | 1995-07-18 | 1999-09-28 | Diversa Corporation | Protein activity screening of clones having DNA from uncultivated microorganisms |
| US5939250A (en) * | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
| US20030215798A1 (en) * | 1997-06-16 | 2003-11-20 | Diversa Corporation | High throughput fluorescence-based screening for novel enzymes |
| GB9603803D0 (en) * | 1996-02-22 | 1996-04-24 | Zeneca Ltd | Production of proteins, plasmids coding therefor and organisms containing such plasmids |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US6242211B1 (en) | 1996-04-24 | 2001-06-05 | Terragen Discovery, Inc. | Methods for generating and screening novel metabolic pathways |
| US5783431A (en) | 1996-04-24 | 1998-07-21 | Chromaxome Corporation | Methods for generating and screening novel metabolic pathways |
| US5763239A (en) * | 1996-06-18 | 1998-06-09 | Diversa Corporation | Production and use of normalized DNA libraries |
| WO1998031837A1 (en) | 1997-01-17 | 1998-07-23 | Maxygen, Inc. | Evolution of whole cells and organisms by recursive sequence recombination |
| US6326204B1 (en) * | 1997-01-17 | 2001-12-04 | Maxygen, Inc. | Evolution of whole cells and organisms by recursive sequence recombination |
| GB9908814D0 (en) * | 1999-04-16 | 1999-06-09 | Celltech Therapeutics Ltd | Process |
| WO2001007300A1 (fr) | 1999-07-28 | 2001-02-01 | Nippon Kayaku Kabushiki-Kaisha | Generateur de gaz |
| US20010049104A1 (en) * | 2000-03-24 | 2001-12-06 | Stemmer Willem P.C. | Methods for modulating cellular and organismal phenotypes |
| US7351813B2 (en) * | 2000-06-20 | 2008-04-01 | The Board Of Trustees Of The Leland Stanford Junior University | Liver-specific gene expression cassettes, and methods of use |
| WO2002059374A1 (en) * | 2001-01-24 | 2002-08-01 | Phytera, Inc. | Method for identifying genes regulating desired cell phenotypes |
| DK1356037T3 (da) * | 2001-01-25 | 2011-06-27 | Evolva Ltd | Bibliotek med en samling af celler |
| ATE375394T1 (de) * | 2001-01-25 | 2007-10-15 | Evolva Ltd | Concatemere unterschiedlich exprimierter multipler gene |
| US8008459B2 (en) * | 2001-01-25 | 2011-08-30 | Evolva Sa | Concatemers of differentially expressed multiple genes |
| DE60228935D1 (de) * | 2001-01-25 | 2008-10-30 | Evolva Ltd | Verfahren zur entwicklung einer zelle mit einem gewünschten phänotyp und entwickelte zellen |
| AU2003237662B2 (en) * | 2002-01-25 | 2008-04-24 | Evolva Ltd | Methods for multiple parameter screening and evolution of cells to produce small molecules with multiple functionalities |
| ATE386810T1 (de) * | 2002-06-14 | 2008-03-15 | Dyax Corp | Rekombination von nukleinsäurebibliotheksmitgliedern |
| US20030235823A1 (en) * | 2002-06-24 | 2003-12-25 | The University Of Alabama | Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation |
-
2003
- 2003-08-01 AT AT03787738T patent/ATE527366T1/de not_active IP Right Cessation
- 2003-08-01 US US10/523,007 patent/US20060252156A1/en not_active Abandoned
- 2003-08-01 DK DK03787738.8T patent/DK1529110T3/da active
- 2003-08-01 WO PCT/DK2003/000521 patent/WO2004016791A1/en not_active Application Discontinuation
- 2003-08-01 EP EP03787738A patent/EP1529110B1/en not_active Expired - Lifetime
- 2003-08-01 AU AU2003247270A patent/AU2003247270A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE527366T1 (de) | 2011-10-15 |
| US20060252156A1 (en) | 2006-11-09 |
| EP1529110A1 (en) | 2005-05-11 |
| WO2004016791A1 (en) | 2004-02-26 |
| AU2003247270A1 (en) | 2004-03-03 |
| EP1529110B1 (en) | 2011-10-05 |
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