DK151009C - Analogifremgangsmaade til fremstilling af benzhydrylsulfinylforbindelser og fysiologisk acceptable syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af benzhydrylsulfinylforbindelser og fysiologisk acceptable syreadditionssalte deraf

Info

Publication number: DK151009C
Authority: DK; Denmark
Prior art keywords: benzhydrylsulphinyl; analogue; compounds; preparation; acid addition
Prior art date: 1975-10-02

Application number

DK437576A

Other languages

English (en)

Other versions

DK437576A (da

DK151009B (da

Inventor

Louis Lafon

Original Assignee

Lafon Labor

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-02

Filing date

1976-09-29

Publication date

1988-02-29

1976-09-29 Application filed by Lafon Labor filed Critical Lafon Labor

1977-04-03 Publication of DK437576A publication Critical patent/DK437576A/da

1987-10-12 Publication of DK151009B publication Critical patent/DK151009B/da

1988-02-29 Application granted granted Critical

1988-02-29 Publication of DK151009C publication Critical patent/DK151009C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Electronic Switches (AREA)

DK437576A 1975-10-02 1976-09-29 Analogifremgangsmaade til fremstilling af benzhydrylsulfinylforbindelser og fysiologisk acceptable syreadditionssalte deraf DK151009C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB4041975		1975-10-02
GB40419/75A GB1520812A (en)	1975-10-02	1975-10-02	Benzhydrylsulphinyl derivatives

Publications (3)

Publication Number	Publication Date
DK437576A DK437576A (da)	1977-04-03
DK151009B DK151009B (da)	1987-10-12
DK151009C true DK151009C (da)	1988-02-29

Family

ID=10414819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK437576A DK151009C (da)	1975-10-02	1976-09-29	Analogifremgangsmaade til fremstilling af benzhydrylsulfinylforbindelser og fysiologisk acceptable syreadditionssalte deraf

Country Status (29)

Country	Link
US (1)	US4066686A (da)
JP (1)	JPS6045186B2 (da)
AT (1)	AT347426B (da)
AU (1)	AU511619B2 (da)
BE (1)	BE846880A (da)
CH (1)	CH614934A5 (da)
CS (1)	CS200195B2 (da)
DE (1)	DE2642511C2 (da)
DK (1)	DK151009C (da)
ES (1)	ES452063A1 (da)
FI (1)	FI63220C (da)
FR (1)	FR2326181A1 (da)
GB (1)	GB1520812A (da)
GE (1)	GEP19960242B (da)
HU (1)	HU175109B (da)
IE (1)	IE43553B1 (da)
IL (1)	IL50599A (da)
LU (1)	LU75909A1 (da)
NL (1)	NL187629C (da)
NO (1)	NO143219C (da)
NZ (1)	NZ182207A (da)
OA (1)	OA05444A (da)
PH (1)	PH12533A (da)
PL (1)	PL105506B1 (da)
PT (1)	PT65648B (da)
SE (1)	SE431088B (da)
SU (1)	SU651693A3 (da)
YU (1)	YU40464B (da)
ZA (1)	ZA765830B (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1106403A (en) *	1977-04-29	1981-08-04	Victor Lafon	Process for preparing (3,4-dichlorophenyl-sulphinyl)- acetamidoxime and its addition salts
FR2528040A1 (fr) *	1982-06-04	1983-12-09	Lafon Labor	Benzhydrylsulfinylethylamines, procede de preparation et utilisation en therapeutique
FR2528041A1 (fr) *	1982-06-04	1983-12-09	Lafon Labor	Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique
GB8320943D0 (en) *	1983-08-03	1983-09-07	Lilly Industries Ltd	Organic compounds
FR2561646B1 (fr) *	1984-03-23	1987-10-09	Lafon Labor	Derives d'acide (a-(alkylaminomethyl)-benzyl)-thioacetique, procede de preparation et utilisation en therapeutique
FR2569186B1 (fr) *	1984-08-20	1986-09-05	Lafon Labor	Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique
DE3604050A1 (de) *	1986-02-08	1987-08-13	Boehringer Mannheim Gmbh	Thioether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
FR2606015B1 (fr) *	1986-08-13	1989-05-19	Lafon Labor	Derives du benzhydrylthiomethane, leurs procedes de preparation et leurs applications en therapeutique
JPH02162176A (ja) *	1988-12-14	1990-06-21	Sanyo Electric Co Ltd	ライトの取付装置
FR2663225B1 (fr) *	1990-06-14	1994-11-04	Lafon Labor	Nouvelle utilisation du modafinil.
FR2708201B1 (fr) *	1993-06-30	1995-10-20	Lafon Labor	Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5571825A (en) *	1995-03-31	1996-11-05	Warner-Lambert Company	Method of selectively inhibiting prostaglandin G/H synthase-2
PL335401A1 (en) *	1997-02-27	2000-04-25	American Cyanamid Co	N-hydroxy-2-(alkyl, aryl or heteroaryl sulphanyl, sulphinyn of sulphonyl)-3-substituted alkyl, aryl or heteroaryl amides as inhibotors of intercellular substance metaloproteinases
US6172057B1 (en)	1997-02-27	2001-01-09	American Cyanamid Company	N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
US6670358B2 (en) *	2000-05-16	2003-12-30	Cephalon, Inc.	Substituted thioacetamides
US6492396B2 (en) *	2000-05-16	2002-12-10	Cephalon, Inc.	Substituted thioacetamides
US6875893B2 (en) *	2002-05-23	2005-04-05	Cephalon, Inc.	Preparations of a sulfinyl acetamide
US6992219B2 (en) *	2002-08-09	2006-01-31	Cephalon France	Modafinil polymorphic forms
EP1437345A1 (en) *	2003-01-13	2004-07-14	Organisation de Synthese Mondiale Orsymonde	Novel method for preparing methyl 2-diphenylmethylsulfinylacetate
CA2514900A1 (en)	2003-01-31	2004-09-10	Alembic Limited	Process for the preparation of 2-[(diphenylmethyl) thio] acetamide
CA2511992A1 (en) *	2003-02-24	2004-09-10	Mallinckrodt Inc.	Process for preparing benzhydrylthioacetamide
ITMI20031298A1 (it) *	2003-06-26	2004-12-27	Erregierre Spa	Processo di preparazione di modafinil forma polimorfa(i).
WO2005046854A2 (en) *	2003-09-12	2005-05-26	Sun Pharmaceutical Industries Limited	A process for the preparation of diphenylmethylsulfinyl derivatives
US7449481B2 (en) *	2004-04-13	2008-11-11	Cephalon, Inc.	Thio-substituted biaryl-methanesulfinyl derivatives
US7119214B2 (en) *	2004-04-13	2006-10-10	Cephalon France	Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US7297817B2 (en) *	2004-04-13	2007-11-20	Cephalon France	Thio-substituted arylmethanesulfinyl derivatives
EP1586560A1 (en) *	2004-04-13	2005-10-19	Cephalon, Inc.	Thio-substituted arylmethanesulfinyl derivatives
US7314875B2 (en) *	2004-04-13	2008-01-01	Cephalon, Inc.	Tricyclic aromatic and bis-phenyl sulfinyl derivatives
US20080317843A1 (en) *	2006-07-12	2008-12-25	Elan Corporation Plc	Nanoparticulate formulations of modafinil
CN101641090B (zh) *	2006-12-19	2012-12-05	亚勒斯有限公司	莫达非尼在制备治疗多动腿综合征的药物中的应用
USD681056S1 (en) *	2012-09-09	2013-04-30	Apple Inc.	Electronic device
AU2014225550C1 (en)	2013-03-08	2017-08-17	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
CN104610108B (zh) *	2015-01-27	2016-03-30	潍坊医学院	一种中枢神经系统药物阿屈非尼中间体化合物的合成方法
US11365195B2 (en)	2017-11-13	2022-06-21	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Atypical inhibitors of monoamine transporters; method of making; and use thereof
KR102126389B1 (ko)	2018-09-14	2020-06-25	셀라이온바이오메드 주식회사	벤즈히드릴티오 아세트아미드 화합물을 유효성분으로 포함하는 간 질환의 예방 또는 치료용 조성물
KR102277739B1 (ko)	2019-12-11	2021-07-15	셀라이온바이오메드 주식회사	벤즈히드릴 티오 아세트아미드 화합물을 유효성분으로 포함하는 섬유화 질환의 치료용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2394597A (en) *	1942-07-09	1946-02-12	Eastman Kodak Co	Preparation of organic dhsocyanates
NL6406688A (da) *	1964-06-05	1965-12-06

1975
- 1975-10-02 GB GB40419/75A patent/GB1520812A/en not_active Expired
1976
- 1976-09-13 CH CH1159776A patent/CH614934A5/xx not_active IP Right Cessation
- 1976-09-22 DE DE2642511A patent/DE2642511C2/de not_active Expired
- 1976-09-24 PH PH18944A patent/PH12533A/en unknown
- 1976-09-27 IE IE2135/76A patent/IE43553B1/en not_active IP Right Cessation
- 1976-09-27 PT PT65648A patent/PT65648B/pt unknown
- 1976-09-28 FR FR7629137A patent/FR2326181A1/fr active Granted
- 1976-09-28 ZA ZA765830A patent/ZA765830B/xx unknown
- 1976-09-29 AT AT720876A patent/AT347426B/de not_active IP Right Cessation
- 1976-09-29 DK DK437576A patent/DK151009C/da not_active IP Right Cessation
- 1976-09-29 OA OA55945A patent/OA05444A/xx unknown
- 1976-09-30 US US05/728,054 patent/US4066686A/en not_active Expired - Lifetime
- 1976-09-30 LU LU75909A patent/LU75909A1/xx unknown
- 1976-10-01 PL PL1976192811A patent/PL105506B1/pl unknown
- 1976-10-01 YU YU2414/76A patent/YU40464B/xx unknown
- 1976-10-01 NO NO763372A patent/NO143219C/no unknown
- 1976-10-01 NL NLAANVRAGE7610929,A patent/NL187629C/xx not_active IP Right Cessation
- 1976-10-01 BE BE171191A patent/BE846880A/xx not_active IP Right Cessation
- 1976-10-01 SU SU762404903A patent/SU651693A3/ru active
- 1976-10-01 IL IL50599A patent/IL50599A/xx unknown
- 1976-10-01 ES ES452063A patent/ES452063A1/es not_active Expired
- 1976-10-01 FI FI762810A patent/FI63220C/fi not_active IP Right Cessation
- 1976-10-01 NZ NZ182207A patent/NZ182207A/xx unknown
- 1976-10-01 HU HU76LA894A patent/HU175109B/hu unknown
- 1976-10-01 CS CS766356A patent/CS200195B2/cs unknown
- 1976-10-01 SE SE7610940A patent/SE431088B/xx not_active IP Right Cessation
- 1976-10-02 JP JP51118908A patent/JPS6045186B2/ja not_active Expired
1978
- 1978-09-29 AU AU18188/76A patent/AU511619B2/en not_active Expired
1992
- 1992-12-09 GE GEAP1992402A patent/GEP19960242B/en unknown

Also Published As

Publication number	Publication date
NL187629B (nl)	1991-07-01
IE43553B1 (en)	1981-03-25
IE43553L (en)	1977-04-02
FI762810A (da)	1977-04-03
FR2326181B1 (da)	1980-08-08
IL50599A (en)	1980-09-16
IL50599A0 (en)	1976-12-31
DE2642511C2 (de)	1986-07-31
NL7610929A (nl)	1977-04-05
SU651693A3 (ru)	1979-03-05
PL105506B1 (pl)	1979-10-31
PH12533A (en)	1979-05-17
AU1818876A (en)	1978-04-06
ES452063A1 (es)	1977-10-01
FI63220B (fi)	1983-01-31
ZA765830B (en)	1977-09-28
DK437576A (da)	1977-04-03
HU175109B (hu)	1980-05-28
AT347426B (de)	1978-12-27
FR2326181A1 (fr)	1977-04-29
CH614934A5 (da)	1979-12-28
YU241476A (en)	1982-02-28
SE7610940L (sv)	1977-04-03
DE2642511A1 (de)	1977-04-14
US4066686A (en)	1978-01-03
NO763372L (da)	1977-04-05
AU511619B2 (en)	1980-08-28
NZ182207A (en)	1978-03-06
SE431088B (sv)	1984-01-16
GB1520812A (en)	1978-08-09
DK151009B (da)	1987-10-12
NL187629C (nl)	1991-12-02
YU40464B (en)	1986-02-28
JPS5246058A (en)	1977-04-12
PT65648A (pt)	1976-10-01
BE846880A (fr)	1977-04-01
CS200195B2 (cs)	1980-08-29
ATA720876A (de)	1978-05-15
NO143219B (no)	1980-09-22
NO143219C (no)	1981-01-07
JPS6045186B2 (ja)	1985-10-08
GEP19960242B (en)	1996-06-01
FI63220C (fi)	1983-05-10
PT65648B (fr)	1978-04-07
OA05444A (fr)	1981-03-31
LU75909A1 (da)	1977-05-11

Publication	Publication Date	Title
DK151009C (da)	1988-02-29	Analogifremgangsmaade til fremstilling af benzhydrylsulfinylforbindelser og fysiologisk acceptable syreadditionssalte deraf
DK160300C (da)	1991-07-29	Analogifremgangsmaade til fremstilling af substituerede phenoxybenzyloxycarbonylderivater og cyclopropancarboxylsyreestere til anvendelse som udgangsforbindelser herved
DK145119C (da)	1983-02-14	Analogifremgangsmaade til fremstilling af phenolethere eller syreadditionssalte deraf
DK151331C (da)	1988-04-25	Analogifremgangsmaade til fremstilling af 5-pyridinyl-2(1h)-pyridinon-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DK145339C (da)	1983-03-21	Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte deraf
DK149594C (da)	1987-03-16	Analogifremgangsmaade til fremstilling af dipeptidderivater eller syreadditionssalte heraf
DK148631C (da)	1986-03-03	Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller fysiologisk acceptable salte og/eller optiske isomerer deraf
DK297076A (da)	1977-01-20	Phenyleddikesyrederivater og fremgangsmade til deres fremstilling
DK148576A (da)	1976-10-19	Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DK125179A (da)	1979-09-29	Fremgangsmaade til fremstilling af disubstituerede 3-cephem-4-catboxylsyrederivater
DK158836C (da)	1991-01-14	Analogifremgangsmaade til fremstilling af terapeutisk aktive anthraquinonderivater
DK146542C (da)	1984-04-09	Analogifremgangsmaade til fremstilling af daunosaminylanthracyclioner
DK496977A (da)	1978-05-10	Fremgangsmaade til fremstilling af 0-alkylerede hydroxylaminer og syreadditionssalte deraf
DK154950C (da)	1989-05-29	Analogifremgangsmaade til fremstilling af 1-(benzazolylalkyl)-piperidinderivater eller de farmaceutisk acceptable syreadditionssalte deraf
DK376276A (da)	1977-02-21	Fremgangsmade til fremstilling af alfa-aminosyreamid
DK149077C (da)	1986-06-16	Analogifremgangsmaade til fremstilling af encephalin-analoge pentapeptidamidderivater eller farmaceutisk acceptable syreadditionssalte deraf
DK359577A (da)	1978-02-15	Fremgangsmade til fremstilling af 2-phenylaminoimidazolin-(2) og syreadditionssalte
DK143278C (da)	1981-12-07	Analogifremgangsmaade til fremstilling af n-(r-tetrahydrofurfuryl)-noroxymorphon eller syreadditionssalte deraf
DK143105C (da)	1981-11-09	Analogifremgangsmaade til fremstilling af aminobenzocycloheptenderivater eller farmaceutisk acceptable additionssalte deraf
DK149625C (da)	1987-01-26	Analogifremgangsmaade til fremstilling af n-substituerede (8-halogen- eller -trifluormethyl-4-quinolylamino)-benzamider eller et farmaceutiskacceptabelt syreadditionssalt deraf
DK153759C (da)	1989-01-09	Analogifremgangsmaade til fremstilling af prostansyrederivater
DK490076A (da)	1977-05-05	Fremgangsmade til fremstilling af 3-aminomethylen-6,7-dimethoxy-2-methyl-oxo1,2,3,4-tetrahydro-1-quinolin-carboxylsyre-estere og mellemprodukter herved
DK144793C (da)	1982-11-01	Analogifremgangsmaade til fremstilling af dihydro- eller tetrahydroiminothiaziner eller farmaceutisk acceptable syreadditionssalte deraf
DK147577C (da)	1985-03-18	Analogifremgangsmaade til fremstilling af 2-phenyl-bicyclooctan- eller -octenaminer eller farmaceutisk acceptable syreadditionssalte deraf
DK143273C (da)	1981-11-30	Analogifremgangsmaade til fremstilling af amidinobenzyloyrimidiner og syreadditionssalte heraf

Legal Events

Date	Code	Title	Description
1996-11-04	PUP	Patent expired