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DK149063C - Analogifremgangsmaade til fremstilling af trh-analoge derivater af histidylprolinamid eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af trh-analoge derivater af histidylprolinamid eller farmaceutisk acceptable syreadditionssalte deraf

Info

Publication number
DK149063C
DK149063C DK463775A DK463775A DK149063C DK 149063 C DK149063 C DK 149063C DK 463775 A DK463775 A DK 463775A DK 463775 A DK463775 A DK 463775A DK 149063 C DK149063 C DK 149063C
Authority
DK
Denmark
Prior art keywords
analogue
prolinamide
histidyl
trh
preparation
Prior art date
Application number
DK463775A
Other languages
Danish (da)
English (en)
Other versions
DK463775A (da
DK149063B (da
Inventor
Eberhard Schwertner
Siegfried Herrling
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2449167A external-priority patent/DE2449167C2/de
Priority claimed from DE19752527723 external-priority patent/DE2527723A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of DK463775A publication Critical patent/DK463775A/da
Publication of DK149063B publication Critical patent/DK149063B/da
Application granted granted Critical
Publication of DK149063C publication Critical patent/DK149063C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK463775A 1974-10-16 1975-10-15 Analogifremgangsmaade til fremstilling af trh-analoge derivater af histidylprolinamid eller farmaceutisk acceptable syreadditionssalte deraf DK149063C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2449167 1974-10-16
DE2449167A DE2449167C2 (de) 1974-10-16 1974-10-16 N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE19752527723 DE2527723A1 (de) 1975-06-21 1975-06-21 Verfahren zur herstellung von dipeptid-derivaten
DE2527723 1975-06-21

Publications (3)

Publication Number Publication Date
DK463775A DK463775A (da) 1976-04-17
DK149063B DK149063B (da) 1986-01-06
DK149063C true DK149063C (da) 1986-06-16

Family

ID=25767820

Family Applications (1)

Application Number Title Priority Date Filing Date
DK463775A DK149063C (da) 1974-10-16 1975-10-15 Analogifremgangsmaade til fremstilling af trh-analoge derivater af histidylprolinamid eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (12)

Country Link
US (1) US4045556A (xx)
JP (1) JPS609518B2 (xx)
CA (1) CA1056818A (xx)
CH (1) CH616913A5 (xx)
DK (1) DK149063C (xx)
ES (1) ES441788A1 (xx)
FR (1) FR2287916A1 (xx)
GB (1) GB1519636A (xx)
IE (1) IE41803B1 (xx)
NL (1) NL183764C (xx)
SE (1) SE408300B (xx)
YU (1) YU39330B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4125578A (en) * 1977-11-09 1979-05-17 Merck & Co Inc Tripeptides
US4182856A (en) * 1978-04-25 1980-01-08 Miles Laboratories, Inc. Reagents for use in binding assays to determine diphenylhydantoin
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
GB2146026A (en) * 1983-09-07 1985-04-11 Tanabe Seiyaku Co Peptides and process for preparing the same
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions
IL75641A (en) * 1984-07-10 1990-11-05 Tanabe Seiyaku Co 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it
IE58849B1 (en) * 1984-12-18 1993-11-17 Gruenenthal Chemie Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis
GB2171101A (en) * 1985-02-20 1986-08-20 Tanabe Seiyaku Co Peptide and processes for preparation of the same
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
WO1994008612A1 (en) * 1992-10-22 1994-04-28 Thomas Peter G New method of protecting central nervous system against damage resulting from cerebrovascular or neuronal compromise
BE1007183A3 (fr) * 1993-06-18 1995-04-18 Solvay Ureines derivees d'alpha, omega-diaminoacides et procede pour leur preparation.
CA2235803A1 (en) * 1995-10-24 1997-05-01 The Trustees Of The University Of Pennsylvania Method of adjusting the circadian rhythm of a mammal
DK0866711T3 (da) * 1995-10-24 2006-11-27 Gruenenthal Gmbh Anvendelse af 6-methyl-5-oxo-3-thiomorpholinylcarbonyl-L-histidyl-L-prolinamid til fremstilling af et farmaceutisk præparat til modvirkning af sövnapnö
DE10025949A1 (de) * 2000-05-26 2001-11-29 Gruenenthal Gmbh Arzneimittel zur Bekämpfung von Atemdepression
KR100557268B1 (ko) 2000-08-31 2006-03-07 시오노기세이야쿠가부시키가이샤 파킨슨씨병 치료제
KR101137503B1 (ko) * 2009-07-14 2012-04-20 웰이앤씨 주식회사 고분자 고체 지지체를 이용한 히스티딜-프롤린아미드 유도체의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5714337B2 (xx) * 1973-02-23 1982-03-24

Also Published As

Publication number Publication date
CH616913A5 (xx) 1980-04-30
US4045556A (en) 1977-08-30
IE41803B1 (en) 1980-03-26
GB1519636A (en) 1978-08-02
SE7509703L (xx) 1976-04-20
DK463775A (da) 1976-04-17
DK149063B (da) 1986-01-06
NL183764B (nl) 1988-08-16
CA1056818A (en) 1979-06-19
JPS5165775A (xx) 1976-06-07
YU232475A (en) 1982-02-28
ES441788A1 (es) 1977-06-16
FR2287916B1 (xx) 1978-07-28
JPS609518B2 (ja) 1985-03-11
NL183764C (nl) 1989-01-16
IE41803L (en) 1976-04-16
YU39330B (en) 1984-10-31
SE408300B (sv) 1979-06-05
FR2287916A1 (fr) 1976-05-14
NL7510288A (nl) 1976-04-21

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