[go: up one dir, main page]

DK1484054T3 - Lægemiddelafgivelsessystem til subkonjunktival indgivelse af fine korn - Google Patents

Lægemiddelafgivelsessystem til subkonjunktival indgivelse af fine korn

Info

Publication number
DK1484054T3
DK1484054T3 DK03705377.4T DK03705377T DK1484054T3 DK 1484054 T3 DK1484054 T3 DK 1484054T3 DK 03705377 T DK03705377 T DK 03705377T DK 1484054 T3 DK1484054 T3 DK 1484054T3
Authority
DK
Denmark
Prior art keywords
delivery system
drug delivery
fine grains
subconjunctival administration
subconjunctival
Prior art date
Application number
DK03705377.4T
Other languages
English (en)
Inventor
Mitsuaki Kuwano
Kazuhito Yamada
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK1484054T3 publication Critical patent/DK1484054T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03705377.4T 2002-02-22 2003-02-21 Lægemiddelafgivelsessystem til subkonjunktival indgivelse af fine korn DK1484054T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002046355 2002-02-22
PCT/JP2003/001897 WO2003070219A1 (fr) 2002-02-22 2003-02-21 Systeme d'administration de medicament destine a administrer de facon subconjonctivale des grains fins

Publications (1)

Publication Number Publication Date
DK1484054T3 true DK1484054T3 (da) 2012-11-26

Family

ID=27750627

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03705377.4T DK1484054T3 (da) 2002-02-22 2003-02-21 Lægemiddelafgivelsessystem til subkonjunktival indgivelse af fine korn

Country Status (13)

Country Link
US (1) US20050089545A1 (da)
EP (1) EP1484054B1 (da)
KR (2) KR20100102749A (da)
CN (1) CN1638734A (da)
AU (1) AU2003211238A1 (da)
CA (1) CA2476935C (da)
CY (1) CY1113423T1 (da)
DK (1) DK1484054T3 (da)
ES (1) ES2393086T3 (da)
PT (1) PT1484054E (da)
SI (1) SI1484054T1 (da)
TW (1) TWI290835B (da)
WO (1) WO2003070219A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2526362C (en) * 2003-05-20 2012-10-09 James F. Collins Ophthalmic drug delivery system
US8545463B2 (en) 2003-05-20 2013-10-01 Optimyst Systems Inc. Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device
WO2005018608A1 (ja) * 2003-08-20 2005-03-03 Santen Pharmaceutical Co., Ltd. 微粒子テノン嚢下投与ドラッグデリバリーシステム
CN100548271C (zh) * 2004-01-20 2009-10-14 阿勒根公司 用于眼部的局部治疗、并优选包括有曲安奈德及透明质酸的组合物
US20060110428A1 (en) 2004-07-02 2006-05-25 Eugene Dejuan Methods and devices for the treatment of ocular conditions
KR20070104645A (ko) * 2005-02-18 2007-10-26 산텐 세이야꾸 가부시키가이샤 스테로이드 화합물의 부작용 경감 또는 회피 방법
EP1868661A1 (en) 2005-04-08 2007-12-26 SurModics, Inc. Sustained release implants for subretinal delivery
JP4982839B2 (ja) * 2005-06-22 2012-07-25 国立大学法人京都大学 硝子体可視化剤
CA2617040A1 (en) * 2005-07-29 2007-02-01 Santen Pharmaceutical Co., Ltd. Non-invasive drug delivery system targeting posterior eye tissue using solid composition
CN1771913B (zh) * 2005-10-30 2011-07-20 沈阳药科大学 用乳化溶剂扩散法制备掩味微球的制备方法
US20070202186A1 (en) * 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
EP2255788B1 (en) * 2008-02-29 2015-07-22 Nagoya Industrial Science Research Institute Liposome for delivery to posterior segment of eye and pharmaceutical composition for disease in posterior segment of eye
CA2750242C (en) 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
WO2012009702A1 (en) 2010-07-15 2012-01-19 Corinthian Ophthalmic, Inc. Method and system for performing remote treatment and monitoring
EP2485691B1 (en) 2010-07-15 2020-03-18 Eyenovia, Inc. Ophthalmic drug delivery
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
EP2593056B1 (en) 2010-07-15 2020-10-21 Eyenovia, Inc. Drop generating device
WO2012051575A2 (en) 2010-10-15 2012-04-19 Iscience Interventional Corporation Device for ocular access
WO2013086015A1 (en) 2011-12-05 2013-06-13 Incept, Llc Medical organogel processes and compositions
JP5960840B2 (ja) 2011-12-12 2016-08-02 アイノビア，インコーポレイティド エジェクタ機構、エジェクタ装置及びそれらの使用方法
KR20150083117A (ko) 2012-11-08 2015-07-16 클리어사이드 바이오메디컬, 인코포레이드 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치
WO2014179615A2 (en) * 2013-05-01 2014-11-06 Dae Won Park Biodegradable copolymers, systems including the copolymers, and methods of forming and using same
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
WO2016011449A1 (en) 2014-07-18 2016-01-21 Allergan, Inc. Suspension compositions of cyclosporin a for subconjunctival and periocular injection
GB201522441D0 (en) 2015-12-18 2016-02-03 Midatech Pharma Wales Ltd Sustained release cyclosporine-loaded microparticles
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
EP3452165A1 (en) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
IL305537B2 (en) 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
WO2018204515A1 (en) 2017-05-02 2018-11-08 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
CA3066408A1 (en) 2017-06-10 2018-12-13 Eyenovia, Inc. Methods and devices for handling a fluid and delivering the fluid to the eye
WO2021119513A1 (en) 2019-12-11 2021-06-17 Eyenovia, Inc. Systems and devices for delivering fluids to the eye and methods of use

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960150A (en) * 1971-09-09 1976-06-01 Alza Corporation Bioerodible ocular device
US5702716A (en) * 1988-10-03 1997-12-30 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
US5185152A (en) * 1990-01-10 1993-02-09 Peyman Gholam A Method and apparatus for controlled release drug delivery to the cornea and anterior chamber of the eye
US5384333A (en) * 1992-03-17 1995-01-24 University Of Miami Biodegradable injectable drug delivery polymer
US5178635A (en) * 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5624962A (en) * 1993-04-16 1997-04-29 Wakamoto Pharmaceutical Co., Ltd. Aqueous drug composition having property of reversible thermosetting gelation
SE9401108D0 (sv) * 1994-03-31 1994-03-31 Leiras Oy Ophthalmic composition I
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
JPH08176016A (ja) * 1994-12-19 1996-07-09 Univ Miami 生分解可能で注射可能な薬物運搬ポリマー
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
US6264970B1 (en) * 1996-06-26 2001-07-24 Takeda Chemical Industries, Ltd. Sustained-release preparation
PT959873E (pt) * 1996-12-20 2006-07-31 Alza Corp Composicao de gel e metodos
US6378526B1 (en) * 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
JP2000247871A (ja) 1999-02-25 2000-09-12 Santen Pharmaceut Co Ltd 網膜または硝子体への薬物放出制御システム
US6395294B1 (en) * 2000-01-13 2002-05-28 Gholam A. Peyman Method of visualization of the vitreous during vitrectomy
JP2002326962A (ja) * 2000-04-03 2002-11-15 Santen Pharmaceut Co Ltd 送達性物質およびそれを利用した薬物デリバリーシステム
US20030194421A1 (en) * 2001-12-28 2003-10-16 Angiotech Pharmaceuticals, Inc. Treatment of uveitis

Also Published As

Publication number Publication date
KR20100102749A (ko) 2010-09-24
PT1484054E (pt) 2012-11-28
TWI290835B (en) 2007-12-11
CA2476935C (en) 2013-05-28
WO2003070219A1 (fr) 2003-08-28
EP1484054B1 (en) 2012-08-29
EP1484054A1 (en) 2004-12-08
ES2393086T3 (es) 2012-12-18
US20050089545A1 (en) 2005-04-28
EP1484054A4 (en) 2007-12-12
AU2003211238A1 (en) 2003-09-09
SI1484054T1 (sl) 2012-12-31
KR20040084931A (ko) 2004-10-06
CN1638734A (zh) 2005-07-13
CY1113423T1 (el) 2016-06-22
CA2476935A1 (en) 2003-08-28
TW200303218A (en) 2003-09-01

Similar Documents

Publication Publication Date Title
DK1484054T3 (da) Lægemiddelafgivelsessystem til subkonjunktival indgivelse af fine korn
DK1530965T3 (da) Kontrolleret frigivelsesleveringssystem til nasal applikation
DK1599186T3 (da) System til administration af transmukalt lægemiddel
ATE405630T1 (de) Wirkstoffabgabesysteme
DK1545662T3 (da) Lægemiddelindgivelsessystem
NO20041315L (no) Medikamentavleveringssystem
EP1568359A4 (en) DRUG DELIVERY SYSTEM HAVING SUB-CONJUNCTIVAL DEPOSIT
EP1509278A4 (en) IMPLANTABLE MEDICAMENT DELIVERY DEVICE
AU2003239433A1 (en) Delivery of drug amines through an inhalation route
ITMI20021660A1 (it) Sistema di somministrazione di farmaco bioadesivo
WO2006060547A3 (en) Systems and methods for intra-oral drug delivery
EP1737357A4 (en) DEVICE FOR TRANSDERING
EP1809362A4 (en) FILTER DELIVERY SYSTEM
AU2003287640A1 (en) Inertial drug delivery system
DK1635875T3 (da) In-situ-geldannende lægemiddeladministrationssystem
DK1635787T3 (da) Bioeroderbare lægemiddelafgivelsessystemer med forhalet frigivelse
EP1406598A4 (en) LYMPHATIC DRUG RELIEF SYSTEM
ATE551051T1 (de) Orales arzneimittelabgabesystem
ITMI20021684A1 (it) Composizione farmaceutica di peptide nasale
GB0304636D0 (en) Pharmaceutical composition for nasal delivery
AU2003212962A8 (en) Transdermal drug delivery systems
NO20043243L (no) Legemiddelleveringssystem for vedvarende frigivelse av glipizid
TWI347847B (en) Drug delivery system for sub-tenon administration of fine particles
DE60321572D1 (de) Transdermales arzneimittelverabreichungssystem
DK1541137T3 (da) Transdermalt delivery system af gestoden