DK144160C - ANALOGY PROCEDURE FOR THE PREPARATION OF 8-THIOMETHYLERGOLIN - Google Patents

ANALOGY PROCEDURE FOR THE PREPARATION OF 8-THIOMETHYLERGOLIN

Info

Publication number: DK144160C
Authority: DK; Denmark
Prior art keywords: thiomethylergolin; preparation; analogy procedure; analogy; procedure
Prior art date: 1974-06-06

Application number

DK249975A

Other languages

Danish (da)

Other versions

DK249975A (en

DK144160B (en

Inventor

E C Kornfeld

N J Bach

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-04

Publication date

1982-06-07

1975-06-04 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1975-12-07 Publication of DK249975A publication Critical patent/DK249975A/en

1981-12-28 Publication of DK144160B publication Critical patent/DK144160B/en

1982-06-07 Application granted granted Critical

1982-06-07 Publication of DK144160C publication Critical patent/DK144160C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK249975A 1974-06-06 1975-06-04 ANALOGY PROCEDURE FOR THE PREPARATION OF 8-THIOMETHYLERGOLIN DK144160C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US47713674		1974-06-06
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines

Publications (3)

Publication Number	Publication Date
DK249975A DK249975A (en)	1975-12-07
DK144160B DK144160B (en)	1981-12-28
DK144160C true DK144160C (en)	1982-06-07

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK249975A DK144160C (en)	1974-06-06	1975-06-04	ANALOGY PROCEDURE FOR THE PREPARATION OF 8-THIOMETHYLERGOLIN

Country Status (27)

Country	Link
US (1)	US3901894A (en)
JP (1)	JPS582946B2 (en)
AR (1)	AR210736A1 (en)
AT (1)	AT344333B (en)
AU (1)	AU507574B2 (en)
BE (1)	BE829887A (en)
BG (1)	BG24812A3 (en)
CA (1)	CA1071623A (en)
CH (1)	CH617196A5 (en)
CS (1)	CS199591B2 (en)
DD (1)	DD120438A5 (en)
DE (1)	DE2524575A1 (en)
DK (1)	DK144160C (en)
ES (1)	ES438313A1 (en)
FR (1)	FR2273542A1 (en)
GB (1)	GB1505296A (en)
HU (1)	HU173590B (en)
IE (1)	IE41474B1 (en)
IL (1)	IL47424A (en)
NL (1)	NL180911C (en)
PH (1)	PH10992A (en)
PL (1)	PL95738B1 (en)
RO (1)	RO77543A (en)
SE (1)	SE420095B (en)
SU (1)	SU613724A3 (en)
YU (1)	YU145575A (en)
ZA (1)	ZA753638B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) *	1977-07-05	1988-03-31	Simes	ERGOLINE-2-THIOETHERS AND THEIR SULPHOXIDES DERIVATIVES
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (en) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	PHARMACEUTICAL PREPARATIONS WITH A CYTOSTATIC EFFECT
FR2526797A1 (en) *	1982-05-12	1983-11-18	Roussel Uclaf	NOVEL 9-OXALYSERGIC ACID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME
CH649998A5 (en) *	1982-08-09	1985-06-28	Sandoz Ag	ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) *	1985-11-13	1988-09-02	Roussel Uclaf	USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
KR100620435B1 (en) *	2001-06-08	2006-09-12	소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스.	Somatostatin-dopamine chimeric analogs
AU2003221494A1 (en) *	2002-03-15	2003-09-29	Antibioticos S.P.A.	Process for the synthesis of pergolide
WO2014070965A2 (en)	2012-11-01	2014-05-08	Ipsen Pharma S.A.S	Somatostatin analogs and dimers thereof
TWI523863B (en)	2012-11-01	2016-03-01	艾普森藥品公司	Somatostatin-dopamine chimeric analogs
WO2016046150A1 (en)	2014-09-25	2016-03-31	Boehringer Ingelheim Vetmedica Gmbh	Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals
WO2019234069A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH507248A (en) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Process for the preparation of D-6-methylergolin (I) ylacetic acid
DE1935556A1 (en) *	1969-07-12	1971-01-21	Hoechst Ag	Process for the production of lysergol
JPS5012398A (en) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/en not_active Expired
- 1975-06-03 SE SE7506327A patent/SE420095B/en not_active IP Right Cessation
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/en not_active IP Right Cessation
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/en not_active Ceased
- 1975-06-03 CS CS753882A patent/CS199591B2/en unknown
- 1975-06-03 HU HU75EI623A patent/HU173590B/en unknown
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-04 DK DK249975A patent/DK144160C/en not_active IP Right Cessation
- 1975-06-04 BG BG030188A patent/BG24812A3/en unknown
- 1975-06-04 IL IL47424A patent/IL47424A/en unknown
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 PL PL1975180897A patent/PL95738B1/en unknown
- 1975-06-05 SU SU752140862A patent/SU613724A3/en active
- 1975-06-05 YU YU01455/75A patent/YU145575A/en unknown
- 1975-06-05 AT AT427975A patent/AT344333B/en not_active IP Right Cessation
- 1975-06-05 ZA ZA3638A patent/ZA753638B/en unknown
- 1975-06-05 RO RO7582445A patent/RO77543A/en unknown
- 1975-06-05 BE BE1006709A patent/BE829887A/en not_active IP Right Cessation
- 1975-06-05 FR FR7517652A patent/FR2273542A1/en active Granted
- 1975-06-06 AR AR259118A patent/AR210736A1/en active
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
- 1975-06-06 ES ES438313A patent/ES438313A1/en not_active Expired
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Also Published As

Publication number	Publication date
GB1505296A (en)	1978-03-30
AT344333B (en)	1978-07-10
IL47424A (en)	1979-11-30
PH10992A (en)	1977-10-20
SE420095B (en)	1981-09-14
IL47424A0 (en)	1975-08-31
US3901894A (en)	1975-08-26
FR2273542A1 (en)	1976-01-02
JPS50160300A (en)	1975-12-25
DK249975A (en)	1975-12-07
AU8182775A (en)	1976-12-09
SU613724A3 (en)	1978-06-30
SE7506327L (en)	1975-12-08
BE829887A (en)	1975-12-05
DE2524575A1 (en)	1975-12-18
FR2273542B1 (en)	1978-10-06
ES438313A1 (en)	1977-05-16
HU173590B (en)	1979-06-28
DD120438A5 (en)	1976-06-12
NL180911B (en)	1986-12-16
NL7506584A (en)	1975-12-09
ATA427975A (en)	1977-11-15
RO77543A (en)	1982-02-26
CS199591B2 (en)	1980-07-31
IE41474B1 (en)	1980-01-16
AR210736A1 (en)	1977-09-15
IE41474L (en)	1975-12-06
JPS582946B2 (en)	1983-01-19
BG24812A3 (en)	1978-05-12
NL180911C (en)	1987-05-18
YU145575A (en)	1982-02-28
ZA753638B (en)	1977-01-26
PL95738B1 (en)	1977-11-30
AU507574B2 (en)	1980-02-21
CA1071623A (en)	1980-02-12
DK144160B (en)	1981-12-28
CH617196A5 (en)	1980-05-14

Publication	Publication Date	Title
DK283175A (en)	1975-12-25	PROCEDURE FOR THE PREPARATION OF BENZOCYCLOAMIDE DERIVATIVES
DK142237C (en)	1981-02-23	CONTINUOUS PROCEDURE FOR THE PREPARATION OF ALCOXYSILAN
DK144160C (en)	1982-06-07	ANALOGY PROCEDURE FOR THE PREPARATION OF 8-THIOMETHYLERGOLIN
DK239075A (en)	1975-12-01	PROCEDURE FOR THE PREPARATION OF IODBENZENE DERIVATIVES
DK144298C (en)	1982-07-12	PROCEDURE FOR THE PREPARATION OF ALKYL-TERT BUTYLETHERS
DK154287C (en)	1989-04-17	ANALOGY PROCEDURE FOR THE PREPARATION OF TRIGLYCERIDES
DK136398C (en)	1978-04-10	PROCEDURE FOR THE PREPARATION OF AN ANALGETIC-ANTIPYRETIC PREPARATION
DK385475A (en)	1976-03-14	PROCEDURE FOR THE PREPARATION OF SECOPROSTAGLANDINS
DK143902C (en)	1982-04-13	ANALOGY PROCEDURE FOR THE PREPARATION OF 8ALFA ERGOLIN-I DERIVATIVES
DK141849C (en)	1980-11-10	PROCEDURE FOR THE PREPARATION OF SEA-VINYLAROMATE PODECOPOLYMERS
DK142455C (en)	1981-08-03	ANALOGY PROCEDURE FOR THE PREPARATION OF THIAPROSTAGLANDINES
DK574075A (en)	1976-06-19	PROCEDURE FOR THE PREPARATION OF 2-METHOXYBENZAMIDES
DK145626C (en)	1983-08-01	ANALOGY PROCEDURE FOR THE PREPARATION OF THIAZOLIDE INGREDIATES
DK140985C (en)	1980-06-02	ANALOGY PROCEDURE FOR THE PREPARATION OF INCIDENTAL DERIVATIVES
DK211075A (en)	1975-11-18	PROCEDURE FOR THE PREPARATION OF ABIETAMIDE DERIVATIVES
DK543875A (en)	1976-06-04	PROCEDURE FOR THE PREPARATION OF HYDROXYPHENYLACETONITRILES
DK583775A (en)	1976-06-21	PROCEDURE FOR THE PREPARATION OF 3-FLUOROBENZODIAZEPINES
DK528475A (en)	1976-05-26	PROCEDURE FOR THE PREPARATION OF TETRAMETHYLETHYLENDIAMINE
DK155316C (en)	1989-08-14	ANALOGY PROCEDURE FOR THE PREPARATION OF OMEGA-NOR-CYCLOALKYL-13,14-DEHYDROPROSTAGLANDINES
DK145696C (en)	1983-07-18	PROCEDURE FOR THE PREPARATION OF 2-ARYLAMINO-2-IMIDAZOLINE DERIVATIVES
DK376975A (en)	1976-02-29	PROCEDURE FOR THE PREPARATION OF ABIETAMIDE DERIVATIVES
DK153155C (en)	1988-10-31	ANALOGY PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINES
DK137539C (en)	1978-09-04	PROCEDURE FOR THE PREPARATION OF 11BETA-FLUORO-4-ANDROSTEN-3-ONERS
DK198175A (en)	1975-11-08	PROCEDURE FOR THE PREPARATION OF INDOLKINOLIZIDE DERIVATIVES
DK593575A (en)	1976-07-01	PROCEDURE FOR THE PREPARATION OF TRICHLORETHYLCHLOROF

Legal Events

Date	Code	Title	Description
1988-08-29	PBP	Patent lapsed