[go: up one dir, main page]

DK143229C - METHOD OF ANALOGUE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) PROPYL) -ALFA-PHENYL-2-PYRIDINE METHANOL OR ACID ADDITION SALTS. - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) PROPYL) -ALFA-PHENYL-2-PYRIDINE METHANOL OR ACID ADDITION SALTS.

Info

Publication number
DK143229C
DK143229C DK73278A DK73278A DK143229C DK 143229 C DK143229 C DK 143229C DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A DK 143229 C DK143229 C DK 143229C
Authority
DK
Denmark
Prior art keywords
alfa
piperidinyl
analogue
cis
propyl
Prior art date
Application number
DK73278A
Other languages
Danish (da)
Other versions
DK73278A (en
DK143229B (en
Inventor
R W Fleming
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,203 external-priority patent/US4112103A/en
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of DK73278A publication Critical patent/DK73278A/en
Publication of DK143229B publication Critical patent/DK143229B/en
Application granted granted Critical
Publication of DK143229C publication Critical patent/DK143229C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK73278A 1977-02-25 1978-02-17 METHOD OF ANALOGUE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) PROPYL) -ALFA-PHENYL-2-PYRIDINE METHANOL OR ACID ADDITION SALTS. DK143229C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/772,203 US4112103A (en) 1976-04-15 1977-02-25 Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols
US77220377 1977-02-25

Publications (3)

Publication Number Publication Date
DK73278A DK73278A (en) 1978-08-26
DK143229B DK143229B (en) 1981-07-27
DK143229C true DK143229C (en) 1981-11-30

Family

ID=25094280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK73278A DK143229C (en) 1977-02-25 1978-02-17 METHOD OF ANALOGUE FOR THE PREPARATION OF (+, -) - CIS-ALFA- (3- (2,6-DIMETHYL-1-PIPERIDINYL) PROPYL) -ALFA-PHENYL-2-PYRIDINE METHANOL OR ACID ADDITION SALTS.

Country Status (11)

Country Link
JP (1) JPS53105479A (en)
AT (1) AT358040B (en)
BE (1) BE864033A (en)
CA (1) CA1096382A (en)
CH (1) CH635095A5 (en)
DE (1) DE2806654A1 (en)
DK (1) DK143229C (en)
ES (1) ES467100A1 (en)
FR (1) FR2381761A1 (en)
GB (1) GB1581096A (en)
PH (1) PH13125A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818914B2 (en) * 1991-04-05 1998-10-30 シャープ株式会社 Multipurpose steam generator
CN116514770B (en) * 2023-05-09 2025-02-07 郑州大学 Method for efficiently preparing pyrmenol from 2-benzylpyridine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (en) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K NEW TERTIARY BUTANOLS WITH BASIC CONSTITUENTS

Also Published As

Publication number Publication date
BE864033A (en) 1978-06-16
JPS53105479A (en) 1978-09-13
FR2381761B1 (en) 1982-03-26
DE2806654A1 (en) 1978-08-31
CH635095A5 (en) 1983-03-15
FR2381761A1 (en) 1978-09-22
DK73278A (en) 1978-08-26
ES467100A1 (en) 1978-11-01
JPS6257632B2 (en) 1987-12-02
DK143229B (en) 1981-07-27
CA1096382A (en) 1981-02-24
PH13125A (en) 1979-12-12
AT358040B (en) 1980-08-11
ATA117078A (en) 1980-01-15
GB1581096A (en) 1980-12-10
DE2806654C2 (en) 1987-07-16

Similar Documents

Publication Publication Date Title
DK462380A (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2,4-DIAMINOQUINAZOLINE COMPOUNDS OR ACID ADDITION SALTS.
DK144010C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2-PIPERAZINYL-6,7-DIMETHOXYQUINAZOLINES OR ACID ADDITION SALTS.
DK150512C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 3-QUINO-LINCARBOXYLIC ACID DERIVATIVES OR ACID ADDITION SALTS.
DK149111C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF HISTIDIN DERIVATIVES OR ACID ADDITION SALTS.
DK147858C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 5'-DEOXY-5-FLUORCYTIDINE OR 5'-DEOXY-5-FLUORURIDINE OR PHYSIOLOGICALLY TOLERABLE ACID ADDITION SALTS.
DK258078A (en) PROCEDURE FOR THE PREPARATION OF 7ALFA-METHOXY-7BETA- (1,3-DITHIETHANE-2-CARBOXAMIDO) CEPHALOSPORANIC ACID DERIVATIVES
DK76578A (en) PROCEDURE FOR THE PREPARATION OF D, 1-5-METHYLTETRAHYDROFOLIC ACID OR SALTS THEREOF
DK144127C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF LYRIC ACID OR 9,10-DIHYDROLYRIC ACIDAMIDS OR ACID ADDITION SALTS THEREOF
DK146281C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6-FLUORO-N-2-IMIDAZOLIDINYLIDE-BENZAMINE OR ACID ADDITION SALTS.
DK154430C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF INDOLO (2,3-A) QUINOLIZIDIN OR ACID ADDITION SALTS
DK75878A (en) PROCEDURE FOR THE PREPARATION OF 20,21, -DI-NOREBURNAMEN INDIVATIVES OR ADDITIONAL SALTS THEREOF
DK140695B (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF 2,4-DIAMO-6,7-DIMETHOXYQUINAZOLINE DERIVATIVES OR ACID ADDITIONAL SALTS THEREOF
DK134580A (en) PROCEDURE FOR THE PREPARATION OF 2,6-DIAMINONEBULARIN OR ACID ADDITION SALTS THEREOF
DK430379A (en) PROCEDURE FOR THE PREPARATION OF 2,6-DIAMINONEBULARIN OR ACID ADDITION SALTS THEREOF
DK150597C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 3,4-BIS-SUBSTITUTED 1,2,5-OXADIAZOL-2-OXIDES OR PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS.
DK148281C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 8A-SUBSTITUTED 8,8A-DESOXY-8,8A-DIHYDROOLEANDOMYCINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS.
DK123578A (en) PROCEDURE FOR PREPARING 3- (2-AMINOETHYLTHIO-6-ETHYL-7-OXO-1-AZABICYCLO- (3,2,0) HEPT-2-EN-2-CARBOXYLIC ACID
DK146540C (en) PROCEDURE FOR THE PREPARATION OF LEUROSIN TYPE ALKALOIDS OR THEIR ACID ADDITION SALTS
DK149628C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 8-SUBSTITUTED-4AE AMINO MACROLIDES OR ACID ADDITION SALTS.
DK157021C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2,3-POLYMETHYLENE-4-OXO-4H-PYRIDO- OR -AZEPINOOE1,2-AAAPYRIMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS OR QUATERA SALTS
DK148036C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF EPIMERE 4 '' - AMINO-ERYTHROMYCIN COMPOUNDS OR ACID ADDITION SALTS.
DK151629C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 3-AMINO-1-BENZOXEPIN-5 (2H) -ON DERIVATIVES OR ACID ADDITION SALTS.
DK57778A (en) PROCEDURE FOR THE PREPARATION OF 1,3-DISUBSTITUTED URINE OR 2-THIORUINE
DK146886C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF BASIC SUBSTITUTED O-PROPYLED OXIMES OR PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS.
DK149889C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF DIBENZO (D, G) (1,3,6) DIOXAZOCINE DERIVATIVES OR ACID ADDITION SALTS THEREOF

Legal Events

Date Code Title Description
PBP Patent lapsed