DK140803B - Process for the preparation of 6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepines. - Google Patents

Process for the preparation of 6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepines.

Info

Publication number: DK140803B
Authority: DK; Denmark
Prior art keywords: benzodiazepines; triazolo; phenyl; preparation
Prior art date: 1973-02-14

Application number

DK73974AA

Other languages

Danish (da)

Other versions

DK140803C (en

Inventor

Martin Gall

Jackson Boling Hester Jr

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-02-14

Filing date

1974-02-13

Publication date

1979-11-19

1974-02-13 Application filed by Upjohn Co filed Critical Upjohn Co

1978-09-19 Priority to DK413978A priority Critical patent/DK413978A/en

1979-11-19 Publication of DK140803B publication Critical patent/DK140803B/en

1980-04-21 Application granted granted Critical

1980-04-21 Publication of DK140803C publication Critical patent/DK140803C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK73974AA 1973-02-14 1974-02-13 Process for the preparation of 6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepines. DK140803B (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK413978A DK413978A (en)	1973-02-14	1978-09-19	PROCEDURE FOR THE PREPARATION OF 6-PHENYL-4H-S-TRIAZOLO (4,3-A) (1,4) BENZODIAZEPINES

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US33237773A	1973-02-14	1973-02-14

Publications (2)

Publication Number	Publication Date
DK140803B true DK140803B (en)	1979-11-19
DK140803C DK140803C (en)	1980-04-21

Family

ID=23297958

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK73974AA DK140803B (en)	1973-02-14	1974-02-13	Process for the preparation of 6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepines.

Country Status (16)

Country	Link
JP (1)	JPS49110699A (en)
AU (1)	AU471038B2 (en)
BE (1)	BE811025A (en)
CA (1)	CA999000A (en)
CH (2)	CH587263A5 (en)
DE (1)	DE2402363A1 (en)
DK (1)	DK140803B (en)
ES (2)	ES422941A1 (en)
FR (1)	FR2217335B1 (en)
GB (3)	GB1454684A (en)
HU (1)	HU168136B (en)
IL (3)	IL44068A (en)
NL (1)	NL7400958A (en)
PH (2)	PH10784A (en)
SE (2)	SE423546B (en)
ZA (1)	ZA74466B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3709898A (en) *	1971-02-09	1973-01-09	Upjohn Co	Process for the production of triazolobenzodiazepines and intermediates

1974
- 1974-01-14 CH CH1421978A patent/CH587263A5/xx not_active IP Right Cessation
- 1974-01-14 CH CH48574A patent/CH586704A5/xx not_active IP Right Cessation
- 1974-01-14 CA CA190,079A patent/CA999000A/en not_active Expired
- 1974-01-18 DE DE2402363A patent/DE2402363A1/en not_active Withdrawn
- 1974-01-22 ZA ZA740466A patent/ZA74466B/en unknown
- 1974-01-23 AU AU64786/74A patent/AU471038B2/en not_active Ceased
- 1974-01-24 NL NL7400958A patent/NL7400958A/xx not_active Application Discontinuation
- 1974-01-24 IL IL44068A patent/IL44068A/en unknown
- 1974-01-24 IL IL49503A patent/IL49503A/en unknown
- 1974-01-30 PH PH15460A patent/PH10784A/en unknown
- 1974-02-04 JP JP49013786A patent/JPS49110699A/ja active Pending
- 1974-02-05 ES ES422941A patent/ES422941A1/en not_active Expired
- 1974-02-07 GB GB2340276A patent/GB1454684A/en not_active Expired
- 1974-02-07 GB GB2340176A patent/GB1454683A/en not_active Expired
- 1974-02-12 SE SE7401858A patent/SE423546B/en not_active IP Right Cessation
- 1974-02-13 FR FR7404855A patent/FR2217335B1/fr not_active Expired
- 1974-02-13 DK DK73974AA patent/DK140803B/en not_active IP Right Cessation
- 1974-02-14 HU HUUO99A patent/HU168136B/hu not_active IP Right Cessation
- 1974-02-14 BE BE140902A patent/BE811025A/en not_active IP Right Cessation
- 1974-04-07 GB GB576474*[A patent/GB1454682A/en not_active Expired
1976
- 1976-03-08 ES ES445860A patent/ES445860A1/en not_active Expired
- 1976-04-30 IL IL49503A patent/IL49503A0/en unknown
1977
- 1977-04-05 PH PH19633A patent/PH11789A/en unknown
1981
- 1981-11-25 SE SE8107017A patent/SE435285B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL44068A (en)	1977-05-31
CA999000A (en)	1976-10-26
GB1454682A (en)	1976-11-03
GB1454684A (en)	1976-11-03
DE2402363A1 (en)	1974-08-22
AU471038B2 (en)	1976-04-08
HU168136B (en)	1976-02-28
DK140803C (en)	1980-04-21
CH586704A5 (en)	1977-04-15
AU6478674A (en)	1975-07-24
FR2217335B1 (en)	1977-06-10
ES445860A1 (en)	1977-05-01
NL7400958A (en)	1974-08-16
PH11789A (en)	1978-07-05
GB1454683A (en)	1976-11-03
IL49503A0 (en)	1976-06-30
JPS49110699A (en)	1974-10-22
CH587263A5 (en)	1977-04-29
SE423546B (en)	1982-05-10
SE8107017L (en)	1981-11-25
IL49503A (en)	1977-05-31
ES422941A1 (en)	1976-09-16
FR2217335A1 (en)	1974-09-06
SE435285B (en)	1984-09-17
BE811025A (en)	1974-08-14
PH10784A (en)	1977-09-06
ZA74466B (en)	1974-12-24
IL44068A0 (en)	1974-05-16

Publication	Publication Date	Title
DK139099B (en)	1978-12-18	Analogous process for the preparation of 5,6-4H-dihydro-s-triazolo (4,3-a) benzodiazepines-1,5.
DK136718B (en)	1977-11-14	Analogous process for the preparation of substituted hexahydro-dibenzo (b, d) -pyran-9-ones.
DK136719B (en)	1977-11-14	Analogous process for the preparation of substituted hexahydro-dibenzo (b, d) -pyrans.
DK138798B (en)	1978-10-30	Process for the preparation of optically active 1,4-benzodiazepin-2-one derivatives.
DK138791B (en)	1978-10-30	Analogous process for the preparation of 2,6-disubstituted phenylaminoguanidine compounds.
DK136075B (en)	1977-08-08	Analogous process for the preparation of 11beta-hydroxy-16-methyl-3-oxo-17alpha-acyloxyandrosta-1,4,15-triene-17beta-carboxylates.
DK139678B (en)	1979-03-26	Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine.
DK138327B (en)	1978-08-14	Analogous process for the preparation of pyrido (1,2a) pyrimidine derivatives.
DK140406B (en)	1979-08-20	Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine.
DK137389B (en)	1978-02-27	Analogous process for the preparation of 11beta-substituted delta4-estreners.
DK135723B (en)	1977-06-13	Analogous process for the preparation of 7alpha-acylthio-3-oxo-D-homo-21,24-dinor-17alpha-chloro-4-ene-23,17a-lactones.
DK132328B (en)	1975-11-24	Analogous process for the preparation of 17beta-hydroxy-16,16-dimethylestr-4-en-3-one.
DK137043B (en)	1978-01-09	Analogous process for the preparation of nitrocarbostyril compounds.
DK132329B (en)	1975-11-24	Process for the preparation of cardenolide-3, alpha- / 2'-deoxy-glycosides /.
DK137381B (en)	1978-02-27	Analogous process for the preparation of N, N'-disubstituted amidines.
DK131855B (en)	1975-09-15	Process for the preparation of 3,4-dihydropyridones.
DK127421B (en)	1973-11-05	Process for the preparation of cardenolide-3 [2 ', 3'-dideoxyglycosides].
DK140480B (en)	1979-09-10	Analogous process for the preparation of 2,8-substituted D-6-alkylergolines.
DK138895B (en)	1978-11-13	Process for the preparation of 8-beta- (2'-pyrimidino-aminomethyl) -ergoline derivatives.
DK136619B (en)	1977-10-31	Process for the preparation of dihydrokanadensolide.
DK140803B (en)	1979-11-19	Process for the preparation of 6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepines.
DK137928B (en)	1978-06-05	Process for the preparation of 5alpha-hydroxygona-9,11-dienes.
DK136776B (en)	1977-11-21	Analogous process for the preparation of 17alpha-alkanoyloxy-D-homopregn-4-ene-3,20-diones.
DK139301B (en)	1979-01-29	Analogous process for the preparation of 5,5,7,7-tetramethylfuro (3,4-e) as-triazines.
DK135133B (en)	1977-03-07	Process for the preparation of 21-fluoro-16alpha, 17alpha-alkylidene dioxy-20-oxo-steroids.

Legal Events

Date	Code	Title	Description
1993-10-25	PBP	Patent lapsed