DK140584A - Fremgangsmaade til fremstilling af carbapenemderivater - Google Patents

Fremgangsmaade til fremstilling af carbapenemderivater Download PDF

Info

Publication number: DK140584A
Authority: DK; Denmark
Prior art keywords: carbapene; derivatives; procedure; preparation; carbapene derivatives
Prior art date: 1983-03-08

Application number

DK140584A

Other languages

English (en)

Other versions

DK140584D0 (da

Inventor

Pierre Dextraze

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-08

Filing date

1984-02-29

Publication date

1984-09-09

1984-02-29 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1984-02-29 Publication of DK140584D0 publication Critical patent/DK140584D0/da

1984-09-09 Publication of DK140584A publication Critical patent/DK140584A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK140584A 1983-03-08 1984-02-29 Fremgangsmaade til fremstilling af carbapenemderivater DK140584A (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US47137883A	1983-03-08	1983-03-08
US49969183A	1983-06-07	1983-06-07
US55729583A	1983-12-01	1983-12-01

Publications (2)

Publication Number	Publication Date
DK140584D0 DK140584D0 (da)	1984-02-29
DK140584A true DK140584A (da)	1984-09-09

Family

ID=27413179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK140584A DK140584A (da)	1983-03-08	1984-02-29	Fremgangsmaade til fremstilling af carbapenemderivater

Country Status (31)

Country	Link
JP (1)	JPH05255250A (da)
KR (1)	KR900002247B1 (da)
AR (1)	AR241016A1 (da)
AT (1)	AT387968B (da)
AU (2)	AU572124B2 (da)
CA (1)	CA1284324C (da)
CH (1)	CH658248A5 (da)
CY (1)	CY1546A (da)
DD (1)	DD228258A5 (da)
DE (1)	DE3408347A1 (da)
DK (1)	DK140584A (da)
ES (2)	ES8505205A1 (da)
FI (1)	FI840863A (da)
FR (1)	FR2542316B1 (da)
GB (1)	GB2136802B (da)
GR (1)	GR81871B (da)
HK (1)	HK82990A (da)
HU (1)	HU193895B (da)
IE (1)	IE57098B1 (da)
IL (1)	IL71149A (da)
IT (1)	IT1178465B (da)
LU (1)	LU85241A1 (da)
NL (1)	NL8400702A (da)
NO (1)	NO166038C (da)
NZ (1)	NZ207346A (da)
OA (1)	OA07674A (da)
PT (1)	PT78211B (da)
SE (2)	SE8401278L (da)
SG (1)	SG35490G (da)
YU (2)	YU46147B (da)
ZW (1)	ZW3884A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683301A (en) *	1982-04-08	1987-07-28	Bristol-Myers Company	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
CA1285940C (en) *	1984-07-02	1991-07-09	Merck & Co., Inc.	Carbapenems having a 2-quaternary heteroarylalkylthio substituent
IE851586L (en) *	1984-07-02	1986-01-02	Interchem Internat S A	I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
US4665169A (en) *	1985-09-11	1987-05-12	Bristol-Myers Company	Carbapenem antibiotics
US4880922A (en) *	1985-11-22	1989-11-14	Bristol-Myers Company	Carbapenems with quaternized heterothioalkylthio substitution at position 2
NZ219892A (en) *	1986-04-15	1991-02-26	Merck & Co Inc	N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
IE910606A1 (en) *	1990-02-23	1991-08-28	Sankyo Co	Carbapenem derivatives having antibiotic activity, their¹preparation and their use
US5712267A (en) *	1991-06-04	1998-01-27	Sankyo Company,. Limited	Carbapenem derivatives, their preparation and their use as antibiotics
KR20060018253A (ko)	2003-06-12	2006-02-28	비티지 인터내셔널 리미티드	정신작용 화합물로서의 시클릭 히드록실아민
FR2921258A1 (fr) *	2007-09-24	2009-03-27	Oreal	Composition tinctoriale comprenant au moins un precurseur incolore disulfures/thiol, proced de coloration a partir de la composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55147284A (en) *	1979-04-17	1980-11-17	Sanraku Inc	Novel beta-lactam derivative and its preparation
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (en) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Process for the preparation of 1-carbapenems, and intermediates for their preparation
EP0060612A1 (en) *	1981-02-04	1982-09-22	Beecham Group Plc	Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
US4552873A (en) *	1981-08-19	1985-11-12	Sankyo Company Limited	Carbapenem compounds, and compositions containing them
EP0074599A1 (en) *	1981-09-09	1983-03-23	Takeda Chemical Industries, Ltd.	5,6-cis-Carbapenem derivatives, their production and use
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics

1984
- 1984-02-29 DK DK140584A patent/DK140584A/da not_active Application Discontinuation
- 1984-02-29 AR AR295877A patent/AR241016A1/es active
- 1984-03-01 NZ NZ207346A patent/NZ207346A/en unknown
- 1984-03-05 FI FI840863A patent/FI840863A/fi not_active Application Discontinuation
- 1984-03-05 NL NL8400702A patent/NL8400702A/xx not_active Application Discontinuation
- 1984-03-05 ZW ZW38/84A patent/ZW3884A1/xx unknown
- 1984-03-05 IL IL71149A patent/IL71149A/xx unknown
- 1984-03-06 GR GR73999A patent/GR81871B/el unknown
- 1984-03-06 CA CA000448904A patent/CA1284324C/en not_active Expired - Fee Related
- 1984-03-06 CH CH1103/84A patent/CH658248A5/de not_active IP Right Cessation
- 1984-03-07 LU LU85241A patent/LU85241A1/fr unknown
- 1984-03-07 GB GB08405984A patent/GB2136802B/en not_active Expired
- 1984-03-07 IE IE549/84A patent/IE57098B1/en not_active IP Right Cessation
- 1984-03-07 HU HU84911A patent/HU193895B/hu not_active IP Right Cessation
- 1984-03-07 DE DE19843408347 patent/DE3408347A1/de not_active Withdrawn
- 1984-03-07 PT PT78211A patent/PT78211B/pt unknown
- 1984-03-07 OA OA58247A patent/OA07674A/xx unknown
- 1984-03-07 AU AU25360/84A patent/AU572124B2/en not_active Ceased
- 1984-03-07 DD DD84260663A patent/DD228258A5/de not_active IP Right Cessation
- 1984-03-07 SE SE8401278A patent/SE8401278L/xx not_active Application Discontinuation
- 1984-03-07 NO NO840865A patent/NO166038C/no unknown
- 1984-03-07 AT AT0076984A patent/AT387968B/de not_active IP Right Cessation
- 1984-03-07 IT IT19945/84A patent/IT1178465B/it active
- 1984-03-07 ES ES530337A patent/ES8505205A1/es not_active Expired
- 1984-03-07 FR FR8403553A patent/FR2542316B1/fr not_active Expired
- 1984-03-08 KR KR1019840001243A patent/KR900002247B1/ko not_active IP Right Cessation
- 1984-03-08 YU YU42084A patent/YU46147B/sh unknown
- 1984-11-02 ES ES537349A patent/ES537349A0/es active Granted
1986
- 1986-03-28 YU YU49486A patent/YU46305B/sh unknown
1987
- 1987-07-20 AU AU75924/87A patent/AU605491B2/en not_active Ceased
1989
- 1989-04-03 SE SE8901162A patent/SE8901162D0/xx not_active Application Discontinuation
1990
- 1990-05-19 SG SG35490A patent/SG35490G/en unknown
- 1990-10-11 HK HK829/90A patent/HK82990A/xx unknown
1991
- 1991-03-22 CY CY1546A patent/CY1546A/xx unknown
- 1991-09-27 JP JP3274949A patent/JPH05255250A/ja active Pending

Also Published As

Publication number	Publication date
YU46147B (sh)	1993-05-28
LU85241A1 (fr)	1984-11-14
NO166038B (no)	1991-02-11
FR2542316B1 (fr)	1988-10-07
NL8400702A (nl)	1984-10-01
IE57098B1 (en)	1992-04-22
ATA76984A (de)	1988-09-15
AU605491B2 (en)	1991-01-17
JPH05255250A (ja)	1993-10-05
NO840865L (no)	1984-09-10
ES530337A0 (es)	1985-05-16
KR840008157A (ko)	1984-12-13
CH658248A5 (de)	1986-10-31
FR2542316A1 (fr)	1984-09-14
AU572124B2 (en)	1988-05-05
GR81871B (da)	1984-12-12
FI840863A (fi)	1984-09-09
AU2536084A (en)	1984-09-13
AT387968B (de)	1989-04-10
CA1284324C (en)	1991-05-21
ES8507145A1 (es)	1985-08-16
IL71149A0 (en)	1984-06-29
GB8405984D0 (en)	1984-04-11
PT78211A (en)	1984-04-01
IT1178465B (it)	1987-09-09
YU49486A (en)	1987-12-31
SE8901162L (sv)	1989-04-03
SE8901162D0 (sv)	1989-04-03
GB2136802B (en)	1987-05-20
OA07674A (fr)	1985-05-23
NZ207346A (en)	1987-01-23
IT8419945A0 (it)	1984-03-07
ES537349A0 (es)	1985-08-16
AR241016A1 (es)	1991-04-30
GB2136802A (en)	1984-09-26
FI840863A0 (fi)	1984-03-05
SE8401278D0 (sv)	1984-03-07
DK140584D0 (da)	1984-02-29
IL71149A (en)	1990-03-19
SE8401278L (sv)	1984-09-09
HUT34980A (en)	1985-05-28
DD228258A5 (de)	1985-10-09
ES8505205A1 (es)	1985-05-16
HK82990A (en)	1990-10-19
YU46305B (sh)	1993-05-28
CY1546A (en)	1991-03-22
PT78211B (en)	1986-08-12
IE840549L (en)	1984-09-08
AR241016A2 (es)	1991-04-30
ZW3884A1 (en)	1984-10-10
HU193895B (en)	1987-12-28
DE3408347A1 (de)	1984-09-13
YU42084A (en)	1986-08-31
NO166038C (no)	1991-05-22
AU7592487A (en)	1987-10-22
KR900002247B1 (ko)	1990-04-07
SG35490G (en)	1990-07-13

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DK372283A (da)	1984-02-18	Fremgangsmaade til fremstilling af desoxyuridinderivater
DK155984D0 (da)	1984-03-14	Fremgangsmade til fremstilling af thiadiazolderivater
DK63683D0 (da)	1983-02-14	Fremgangsmade til fremstilling af cephemderivater
DK323083D0 (da)	1983-07-13	Fremgangsmade til fremstilling af 19-thio-androstanderivater
DK312584D0 (da)	1984-06-26	Fremgangsmaade til fremstilling af quinonderivater
DK140584D0 (da)	1984-02-29	Fremgangsmaade til fremstilling af carbapenemderivater
DK427083D0 (da)	1983-09-19	Fremgangsmade til fremstilling af cephemderivater
DK435483D0 (da)	1983-09-23	Fremgangsmade til fremstilling af fenylcyklobutylderivater
DK261883D0 (da)	1983-06-08	Fremgangsmade til fremstilling af prostaglandin-d-derivater
DK162230C (da)	1992-03-02	Fremgangsmaade til fremstilling af 2-thiacephemderivater
DK426683A (da)	1984-03-31	Fremgangsmaade til fremstilling af oxacephalosporinderivater
DK317283D0 (da)	1983-07-08	Fremgangsmade til fremstilling af thiadiazolderivater
DK340483D0 (da)	1983-07-25	Fremgangsmade til fremstilling af fluoralkylerede carbapenemderivater
DK287484A (da)	1984-12-14	Fremgangsmaade til fremstilling af acetaldehyd
DK165583D0 (da)	1983-04-15	Fremgangsmade til fremstilling af furanderivater
DK482983A (da)	1984-04-22	Fremgangsmaade til fremstilling af phenylderivater
DK605384A (da)	1985-06-28	Fremgangsmaade til fremstilling af azetidinoner
DK542383D0 (da)	1983-11-25	Fremgangsmade til fremstilling af acridanonderivater
DK164283D0 (da)	1983-04-14	Fremgangsmade til fremstilling af benzimidazolderivater
DK157874C (da)	1990-07-30	Fremgangsmaade til fremstilling af azinomethylrifamyciner
DK96383D0 (da)	1983-02-28	Fremgangsmade til fremstilling af 3-azetidinylaetyl-1-fenyl-2-imidazolidinonderivater
DK88283D0 (da)	1983-02-24	Fremgangsmade til fremstilling af triazolderivater

Legal Events

Date	Code	Title	Description
1989-03-20	PBP	Patent lapsed
1994-08-22	AHS	Application shelved for other reasons than non-payment