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DK140389A - ANTIHYPERTENSIVE PREPARATION - Google Patents

ANTIHYPERTENSIVE PREPARATION

Info

Publication number
DK140389A
DK140389A DK140389A DK140389A DK140389A DK 140389 A DK140389 A DK 140389A DK 140389 A DK140389 A DK 140389A DK 140389 A DK140389 A DK 140389A DK 140389 A DK140389 A DK 140389A
Authority
DK
Denmark
Prior art keywords
formula
image
antihypertensive preparation
pyridazodiazepine
sequelae
Prior art date
Application number
DK140389A
Other languages
Danish (da)
Other versions
DK140389D0 (en
Inventor
Cornelis Kleinbloesem
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK140389D0 publication Critical patent/DK140389D0/en
Publication of DK140389A publication Critical patent/DK140389A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)

Abstract

Pharmaceutical combination preparations containing a beta -blocker of the formula <IMAGE> and a pyridazodiazepine of the formula <IMAGE> in which R, R<1>, R<2>, R<3>, R<4> and R<5> have the meaning stated in claim 1, have a pronounced lowering effect on blood pressure without increasing the heart rate and are accordingly suitable for controlling or preventing hypertension and its sequelae.
DK140389A 1988-03-24 1989-03-21 ANTIHYPERTENSIVE PREPARATION DK140389A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH111488 1988-03-24

Publications (2)

Publication Number Publication Date
DK140389D0 DK140389D0 (en) 1989-03-21
DK140389A true DK140389A (en) 1989-09-25

Family

ID=4202814

Family Applications (1)

Application Number Title Priority Date Filing Date
DK140389A DK140389A (en) 1988-03-24 1989-03-21 ANTIHYPERTENSIVE PREPARATION

Country Status (13)

Country Link
EP (1) EP0334164B1 (en)
JP (1) JPH01283224A (en)
KR (1) KR890014116A (en)
AT (1) ATE96322T1 (en)
AU (1) AU616249B2 (en)
CS (1) CS395291A3 (en)
DE (1) DE58905990D1 (en)
DK (1) DK140389A (en)
HU (1) HU206612B (en)
IL (1) IL89654A (en)
MC (1) MC2019A1 (en)
MX (1) MX9203171A (en)
ZA (1) ZA892061B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59409631D1 (en) * 1993-07-15 2001-02-15 Hoffmann La Roche Pharmaceutical combination containing an inhibitor of the renin-angiotensin system and an endothelin antagonist
EP2537534B1 (en) 2011-06-22 2014-12-17 Hexal AG Esters of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their therapeutic use.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW11586A1 (en) * 1985-07-01 1987-12-30 Hoffmann La Roche Bicyclic compounds
DE3542794A1 (en) * 1985-12-04 1987-06-11 Bayer Ag ANTI-HYPERTENSIVE COMBINATION PREPARATION

Also Published As

Publication number Publication date
CS395291A3 (en) 1992-06-17
HUT50281A (en) 1990-01-29
AU616249B2 (en) 1991-10-24
MC2019A1 (en) 1990-02-23
EP0334164A3 (en) 1990-05-23
EP0334164A2 (en) 1989-09-27
DK140389D0 (en) 1989-03-21
ZA892061B (en) 1989-11-29
IL89654A0 (en) 1989-09-28
HU206612B (en) 1992-12-28
ATE96322T1 (en) 1993-11-15
MX9203171A (en) 1992-07-01
AU3145689A (en) 1989-09-28
DE58905990D1 (en) 1993-12-02
JPH01283224A (en) 1989-11-14
EP0334164B1 (en) 1993-10-27
IL89654A (en) 1993-06-10
KR890014116A (en) 1989-10-21

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment