DK135286B - Fremgangsmåde til fremstilling af 3-iminomethylderivater af rifamycin SV. - Google Patents

Fremgangsmåde til fremstilling af 3-iminomethylderivater af rifamycin SV.

Info

Publication number: DK135286B
Authority: DK; Denmark
Prior art keywords: rifamycin; preparation; iminomethyl; derivatives; iminomethyl derivatives
Prior art date: 1973-07-25

Application number

DK284774AA

Other languages

English (en)

Other versions

DK284774A (da

DK135286C (da

Inventor

Leonardo Marsili

Carmine Pasqualucci

Original Assignee

Archifar Ind Chim Trentino

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-07-25

Filing date

1974-05-24

Publication date

1977-03-28

1973-07-25 Priority claimed from IT2706673A external-priority patent/IT1043857B/it

1974-01-24 Priority claimed from IT1977474A external-priority patent/IT1054154B/it

1974-05-24 Application filed by Archifar Ind Chim Trentino filed Critical Archifar Ind Chim Trentino

1975-01-26 Publication of DK284774A publication Critical patent/DK284774A/da

1977-03-28 Publication of DK135286B publication Critical patent/DK135286B/da

1977-09-05 Application granted granted Critical

1977-09-05 Publication of DK135286C publication Critical patent/DK135286C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK284774AA 1973-07-25 1974-05-24 Fremgangsmåde til fremstilling af 3-iminomethylderivater af rifamycin SV. DK135286B (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2706673A IT1043857B (it)	1973-07-25	1973-07-25	Derivati delle rifapicime procedimento della loro sintesi e loro impiego quali intermeni per la produzione di sofamicine
IT1977474A IT1054154B (it)	1974-01-24	1974-01-24	Procedimento per la preparazione di ossazino rifamione

Publications (3)

Publication Number	Publication Date
DK284774A DK284774A (da)	1975-01-26
DK135286B true DK135286B (da)	1977-03-28
DK135286C DK135286C (da)	1977-09-05

Family

ID=26327298

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK284774AA DK135286B (da)	1973-07-25	1974-05-24	Fremgangsmåde til fremstilling af 3-iminomethylderivater af rifamycin SV.
DK284874A DK284874A (da)	1973-07-25	1974-05-24	1,3-oxazino (5,6-c)rifamyciner og fremgangsmade til fremstilling deraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK284874A DK284874A (da)	1973-07-25	1974-05-24	1,3-oxazino (5,6-c)rifamyciner og fremgangsmade til fremstilling deraf

Country Status (25)

Country	Link
US (3)	US3925366A (da)
JP (2)	JPS5339440B2 (da)
AR (2)	AR207762A1 (da)
AT (2)	AT334530B (da)
BE (2)	BE815122A (da)
CA (2)	CA1024139A (da)
CH (2)	CH611296A5 (da)
DD (2)	DD112133A5 (da)
DE (2)	DE2428387A1 (da)
DK (2)	DK135286B (da)
ES (2)	ES429059A1 (da)
FI (2)	FI153574A (da)
FR (2)	FR2257297B1 (da)
GB (2)	GB1454802A (da)
HU (2)	HU167983B (da)
IE (2)	IE39388B1 (da)
IN (2)	IN139074B (da)
NL (2)	NL7409892A (da)
NO (2)	NO142305C (da)
PH (1)	PH13691A (da)
PL (1)	PL91647B1 (da)
RO (1)	RO63865A (da)
SE (2)	SE407803B (da)
SU (2)	SU613725A3 (da)
YU (2)	YU36719B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR207762A1 (es) *	1973-07-25	1976-10-29	Archifar Ind Chim Trentino	Procedimiento para la preparacion de 3-((4-metil-1-piperazin-1-il)-imino)-metil-rifamicina sv o rifampicina
GB1576886A (en) *	1977-04-20	1980-10-15	Lepetit Spa	Rifamycin derivatives
US4179439A (en) *	1977-07-01	1979-12-18	Intreprinderea De Antibiotice Iasi	Rifamycins and method for their preparation
JPS5473798A (en) *	1977-11-15	1979-06-13	Kanebo Ltd	Novel 1,3-oxazino (5,6-c) rifamycin derivative
JPS5473799A (en) *	1977-11-16	1979-06-13	Kanebo Ltd	Preparation of 1,3-oxazino (5,6-c) rifamycin derivative
GB1594134A (en) *	1977-11-25	1981-07-30	Holco Investment Inc	Rifamycins
JPS5484600A (en) *	1977-12-15	1979-07-05	Kanebo Ltd	Preparation of 1,3-oxazino 5,6-c rifamycin derivative
JPS5776597A (en) *	1980-10-30	1982-05-13	Kiyouritsu Kurieiteibu Asoshie	Electric musical instrument
JPS58115705U (ja) *	1982-02-01	1983-08-08	株式会社ニコン	カメラのフアインダ光学系
GB8308166D0 (en) *	1983-03-24	1983-05-05	Erba Farmitalia	Preparation of azinomethyl-rifamycins
GB8318072D0 (en) *	1983-07-04	1983-08-03	Lepetit Spa	Water-soluble rifampicin derivatives
JP2001504830A (ja) *	1996-11-19	2001-04-10	ジョージタウンユニバーシティ	ヘレグリン拮抗因子及びその利用方法
US20090275594A1 (en) *	2008-05-05	2009-11-05	Macielag Mark J	3-hydrazone piperazinyl rifamycin derivatives useful as antimicrobial agents
CN103755723B (zh) *	2014-02-07	2016-04-20	天津大学	一种利福平i晶型的制备方法
CN103951677B (zh) *	2014-03-17	2016-04-06	四川省长征药业股份有限公司	利福喷丁的制备方法
CN106632394A (zh) *	2016-11-15	2017-05-10	南京工业大学	一种利用釜式反应装置与微通道反应装置串联反应制备利福平的方法
CN106749326A (zh) *	2016-11-28	2017-05-31	南京工业大学	一种由利福霉素s钠盐连续生产制备利福平的方法
CN111848639A (zh) *	2020-07-09	2020-10-30	华东理工大学	一种合成利福平的工艺方法
KR102688151B1 (ko)	2021-12-28	2024-07-24	주식회사 종근당바이오	Mnp가 저감된 리팜피신의 신규 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1090115A (en) *	1964-04-02	1967-11-08	Lepetit Spa	Mannich bases of rifamycin sv
FR208F (da) *	1964-07-31
DE1795567C3 (de) *	1964-07-31	1975-05-28	Gruppo Lepetit S.P.A., Mailand (Italien)	Rifamycin-SV-Derivate und Verfahren zu ihrer Herstellung
NL145554B (nl) *	1967-06-07	1975-04-15	Lepetit Spa	Werkwijze voor het bereiden van een 3-formylrifamycine sv-derivaat
AR207762A1 (es) *	1973-07-25	1976-10-29	Archifar Ind Chim Trentino	Procedimiento para la preparacion de 3-((4-metil-1-piperazin-1-il)-imino)-metil-rifamicina sv o rifampicina

1974
- 1974-01-01 AR AR254828A patent/AR207762A1/es active
- 1974-01-01 AR AR254829A patent/AR207763A1/es active
- 1974-05-07 SE SE7406073A patent/SE407803B/xx not_active IP Right Cessation
- 1974-05-07 SE SE7406074A patent/SE393112B/xx not_active IP Right Cessation
- 1974-05-08 FR FR7415837A patent/FR2257297B1/fr not_active Expired
- 1974-05-08 GB GB2025774A patent/GB1454802A/en not_active Expired
- 1974-05-08 GB GB2025674A patent/GB1454801A/en not_active Expired
- 1974-05-09 IN IN1039/CAL/74A patent/IN139074B/en unknown
- 1974-05-09 IN IN1038/CAL/74A patent/IN138735B/en unknown
- 1974-05-14 IE IE1034/74A patent/IE39388B1/xx unknown
- 1974-05-14 YU YU1324/74A patent/YU36719B/xx unknown
- 1974-05-14 YU YU1325/74A patent/YU36720B/xx unknown
- 1974-05-14 IE IE1035/74A patent/IE39389B1/xx unknown
- 1974-05-15 NO NO741763A patent/NO142305C/no unknown
- 1974-05-15 NO NO741764A patent/NO741764L/no unknown
- 1974-05-16 BE BE144391A patent/BE815122A/xx unknown
- 1974-05-17 FI FI1535/74A patent/FI153574A/fi unknown
- 1974-05-21 RO RO7400078880A patent/RO63865A/ro unknown
- 1974-05-23 FI FI1575/74A patent/FI60397C/fi active
- 1974-05-23 US US472886A patent/US3925366A/en not_active Expired - Lifetime
- 1974-05-23 US US05/472,887 patent/US3963705A/en not_active Expired - Lifetime
- 1974-05-23 PL PL1974171342A patent/PL91647B1/pl unknown
- 1974-05-24 DK DK284774AA patent/DK135286B/da unknown
- 1974-05-24 CA CA200,755A patent/CA1024139A/en not_active Expired
- 1974-05-24 DK DK284874A patent/DK284874A/da unknown
- 1974-05-31 CA CA201,355A patent/CA1022548A/en not_active Expired
- 1974-06-10 DD DD179054A patent/DD112133A5/xx unknown
- 1974-06-12 DE DE19742428387 patent/DE2428387A1/de active Pending
- 1974-06-17 PH PH15952A patent/PH13691A/en unknown
- 1974-06-17 AT AT496174A patent/AT334530B/de not_active IP Right Cessation
- 1974-07-04 JP JP7592774A patent/JPS5339440B2/ja not_active Expired
- 1974-07-04 JP JP7592874A patent/JPS5314080B2/ja not_active Expired
- 1974-07-05 SU SU2041832A patent/SU613725A3/ru active
- 1974-07-09 SU SU742040820A patent/SU576943A3/ru active
- 1974-07-10 DE DE2433105A patent/DE2433105A1/de active Granted
- 1974-07-11 DD DD179869A patent/DD112267A5/xx unknown
- 1974-07-17 FR FR7424949A patent/FR2245631B1/fr not_active Expired
- 1974-07-18 BE BE146706A patent/BE817823A/xx not_active IP Right Cessation
- 1974-07-19 AT AT596774A patent/AT334531B/de not_active IP Right Cessation
- 1974-07-22 NL NL7409892A patent/NL7409892A/xx unknown
- 1974-07-23 NL NLAANVRAGE7409955,A patent/NL181992C/xx not_active IP Right Cessation
- 1974-07-24 CH CH1019974A patent/CH611296A5/xx not_active IP Right Cessation
- 1974-07-24 HU HUAI240A patent/HU167983B/hu unknown
- 1974-07-24 ES ES429059A patent/ES429059A1/es not_active Expired
- 1974-07-24 CH CH1020074A patent/CH615683A5/de not_active IP Right Cessation
- 1974-07-24 ES ES429060A patent/ES429060A1/es not_active Expired
- 1974-07-24 HU HUAI239A patent/HU168723B/hu unknown
1983
- 1983-04-11 US US06/483,683 patent/USRE31587E/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FI153574A (da)	1975-01-26
CH611296A5 (da)	1979-05-31
DE2433105C2 (da)	1988-03-31
CA1024139A (en)	1978-01-10
IE39389B1 (en)	1978-09-27
ES429060A1 (es)	1976-08-16
SU613725A1 (da)	1978-06-30
SE7406074L (da)	1975-01-27
DE2428387A1 (de)	1975-02-13
BE815122A (fr)	1974-09-16
NL7409892A (nl)	1975-01-28
US3963705A (en)	1976-06-15
NO741763L (da)	1975-02-24
JPS5339440B2 (da)	1978-10-21
FI60397C (fi)	1982-01-11
AR207763A1 (es)	1976-10-29
IN139074B (da)	1976-05-01
YU36719B (en)	1984-08-31
SE7406073L (da)	1975-01-27
AT334530B (de)	1976-01-25
AT334531B (de)	1976-01-25
DK284874A (da)	1975-01-26
SU613725A3 (ru)	1978-06-30
FI157574A (da)	1975-01-26
ATA496174A (de)	1976-05-15
AU6990574A (en)	1975-12-11
DK284774A (da)	1975-01-26
DD112267A5 (da)	1975-04-05
BE817823A (fr)	1974-11-18
HU167983B (da)	1976-02-28
DK135286C (da)	1977-09-05
FR2245631A1 (da)	1975-04-25
ES429059A1 (es)	1976-08-16
IE39388L (en)	1975-01-25
NL181992B (nl)	1987-07-16
IE39389L (en)	1975-01-25
ATA596774A (de)	1976-05-15
FR2257297A1 (da)	1975-08-08
IN138735B (da)	1976-03-27
SE393112B (sv)	1977-05-02
PL91647B1 (da)	1977-03-31
AU6991074A (en)	1975-12-11
FI60397B (fi)	1981-09-30
PH13691A (en)	1980-09-01
FR2257297B1 (da)	1978-07-21
AR207762A1 (es)	1976-10-29
GB1454802A (en)	1976-11-03
US3925366A (en)	1975-12-09
JPS5042021A (da)	1975-04-16
SE407803B (sv)	1979-04-23
USRE31587E (en)	1984-05-22
CA1022548A (en)	1977-12-13
NO142305C (no)	1980-07-30
FR2245631B1 (da)	1978-09-15
RO63865A (fr)	1979-01-15
YU36720B (en)	1984-08-31
YU132574A (en)	1981-11-13
IE39388B1 (en)	1978-09-27
NO741764L (da)	1975-02-24
DD112133A5 (da)	1975-03-20
JPS5314080B2 (da)	1978-05-15
NL7409955A (nl)	1975-01-28
SU576943A3 (ru)	1977-10-15
JPS5041897A (da)	1975-04-16
YU132474A (en)	1981-11-13
NL181992C (nl)	1987-12-16
GB1454801A (en)	1976-11-03
NO142305B (no)	1980-04-21
HU168723B (da)	1976-07-28
DE2433105A1 (de)	1975-02-06
CH615683A5 (da)	1980-02-15

Publication	Publication Date	Title
DK137329B (da)	1978-02-20	Analogifremgangsmåde til fremstilling af 2-karbalkoksyaminobenzimidazolderivater.
DK134345B (da)	1976-10-25	Analogifremgangsmåde til fremstilling af 4-hydroxymethyl-1-phthalazonderivater.
DK135286B (da)	1977-03-28	Fremgangsmåde til fremstilling af 3-iminomethylderivater af rifamycin SV.
DK135376B (da)	1977-04-18	Fremgangsmåde til fremstilling af piperazinylquinazolin-forbindelser.
DK137835B (da)	1978-05-16	Analogifremgangsmåde til fremstilling af thienothiazinderivater.
DK134031B (da)	1976-08-30	Fremgangsmåde til fremstilling af et endo-beta-glucanase-præparat.
DK137389B (da)	1978-02-27	Analogifremgangsmåde til fremstilling af 11beta-substituerede delta4-østrener.
DK138759B (da)	1978-10-23	Fremgangsmåde til fremstilling af D-ribose.
DK134279B (da)	1976-10-11	Analogifremgangsmåde til fremstilling af cycloalkylphenoxycarboxylsyrederivater.
DK138796B (da)	1978-10-30	Analogifremgangsmåde til fremstilling af 2-carboxypyrazin-4-oxidderivater.
DK140411B (da)	1979-08-20	Fremgangsmåde til fremstilling af deacetoxycephalosporin C.
DK139716B (da)	1979-04-02	Analogifremgangsmåde til fremstilling af 4-aminoamfetaminderivater.
DK135685B (da)	1977-06-06	Analogifremgangsmåde til fremstilling af morfolinderivater.
DK137043B (da)	1978-01-09	Analogifremgangsmåde til fremstilling af nitrocarbostyrilforbindelser.
DK139682B (da)	1979-03-26	Analogifremgangsmåde til fremstilling af eburnameninderivater.
DK135122B (da)	1977-03-07	Analogifremgangsmåde til fremstilling af 4-aryl-5-aminoalkyl-4-oxazolin-2-onderivater.
DK140670B (da)	1979-10-22	Analogifremgangsmåde til fremstilling af ergopeptinderivater.
DK135943B (da)	1977-07-18	Fremgangsmåde til fremstilling af propanolaminderivater.
DK136619B (da)	1977-10-31	Fremgangsmåde til fremstilling af dihydrokanadensolid.
DK135120B (da)	1977-03-07	Analogifremgangsmåde til fremstilling af imidazolidinderivater.
DK136652B (da)	1977-11-07	Fremgangsmåde til fremstilling af thieno-pyridinderivater.
DK136216B (da)	1977-09-05	Analogifremgangsmåde til fremstilling af aminopropanolderivater.
DK135995B (da)	1977-07-25	Analogifremgangsmåde til fremstilling af imidazolderivater af rifamycin SV eller af 25-desacetylrifamycin SV.
DK135809B (da)	1977-06-27	Analogifremgangsmåde til fremstilling af 4-oxo-benzocycloheptathiophenderivater.
DK134240B (da)	1976-10-04	Fremgangsmåde til fremstilling af bicyclomycin.