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DK1342780T3 - Forbedret fremgangsmåde til dyrkning af pattedyrceller in vitro - Google Patents

Forbedret fremgangsmåde til dyrkning af pattedyrceller in vitro

Info

Publication number
DK1342780T3
DK1342780T3 DK03004806T DK03004806T DK1342780T3 DK 1342780 T3 DK1342780 T3 DK 1342780T3 DK 03004806 T DK03004806 T DK 03004806T DK 03004806 T DK03004806 T DK 03004806T DK 1342780 T3 DK1342780 T3 DK 1342780T3
Authority
DK
Denmark
Prior art keywords
vitro
mammalian cells
improved method
culturing mammalian
citrate
Prior art date
Application number
DK03004806T
Other languages
English (en)
Inventor
Ulrich Behrendt
Horst Eberhardt
Berthold Szperalski
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27798778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1342780(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1342780T3 publication Critical patent/DK1342780T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK03004806T 2002-03-05 2003-03-04 Forbedret fremgangsmåde til dyrkning af pattedyrceller in vitro DK1342780T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02004366 2002-03-05

Publications (1)

Publication Number Publication Date
DK1342780T3 true DK1342780T3 (da) 2005-12-12

Family

ID=27798778

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03004806T DK1342780T3 (da) 2002-03-05 2003-03-04 Forbedret fremgangsmåde til dyrkning af pattedyrceller in vitro

Country Status (11)

Country Link
US (1) US7390660B2 (da)
EP (1) EP1342780B1 (da)
JP (2) JP4476554B2 (da)
KR (1) KR100576589B1 (da)
CN (1) CN100398640C (da)
AT (1) ATE304047T1 (da)
CA (1) CA2417689C (da)
DE (1) DE60301510T2 (da)
DK (1) DK1342780T3 (da)
ES (1) ES2248657T3 (da)
MX (1) MXPA03001487A (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101573529B1 (ko) 2005-01-05 2015-12-01 추가이 세이야쿠 가부시키가이샤 세포의 배양 방법 및 그 이용
DE102005046225B4 (de) 2005-09-28 2012-01-05 Cellca Gmbh Verbessertes Zellkulturmedium
EP2527425A1 (en) 2006-09-13 2012-11-28 Abbott Laboratories Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
TW200902708A (en) 2007-04-23 2009-01-16 Wyeth Corp Methods of protein production using anti-senescence compounds
WO2009023562A2 (en) * 2007-08-09 2009-02-19 Wyeth Use of perfusion to enhance production of fed-batch cell culture in bioreactors
WO2010048192A2 (en) 2008-10-20 2010-04-29 Abbott Laboratories Viral inactivation during purification of antibodies
NZ592095A (en) * 2008-10-20 2013-01-25 Abbott Lab Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography
ES2981683T3 (es) 2009-10-26 2024-10-10 Hoffmann La Roche Procedimiento para la producción de una inmunoglobulina glucosilada
EP3147355B1 (en) 2010-12-27 2020-07-22 Kyowa Kirin Co., Ltd. Method for preparing aqueous solution containing culture medium and chelating agent
EP2702077A2 (en) 2011-04-27 2014-03-05 AbbVie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
BR112015004467A2 (pt) 2012-09-02 2017-03-21 Abbvie Inc método para controlar a heterogeneidade de proteínas
WO2014143205A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
EP3052640A2 (en) 2013-10-04 2016-08-10 AbbVie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
SG11201601681QA (en) 2013-10-11 2016-04-28 Regeneron Pharma Metabolically optimized cell culture
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
JPWO2015155975A1 (ja) 2014-04-07 2017-04-13 東洋製罐グループホールディングス株式会社 動物細胞用培養液、及び培養容器
EP4486777A1 (en) 2022-03-02 2025-01-08 Regeneron Pharmaceuticals, Inc. Manufacturing process for high titer antibody

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328844A (en) 1990-05-09 1994-07-12 University Of Colorado Foundation, Inc. Culture media for mammalian cells
EP0593539A1 (en) 1991-06-21 1994-04-27 Novo Nordisk A/S Iron chelate culture medium additive
JP3046415B2 (ja) * 1991-10-04 2000-05-29 日水製薬株式会社 浮遊細胞用無血清合成培地
US5719050A (en) * 1993-12-24 1998-02-17 Eiken Chemical Co., Ltd. Animal cell culturing media containing N-acetyl-L-glutamic acid
JPH0870858A (ja) * 1993-12-24 1996-03-19 Eiken Chem Co Ltd 動物細胞培養用培地
US5856179A (en) * 1994-03-10 1999-01-05 Genentech, Inc. Polypeptide production in animal cell culture
WO1998041611A1 (en) 1997-03-20 1998-09-24 Regents Of The University Of Minnesota Process for the continuous culture of cells
UA74557C2 (en) * 1999-09-03 2006-01-16 Applied Research Systems A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
US6762053B2 (en) * 2000-06-09 2004-07-13 Vitrolife, Inc. Mammalian gamete and embryo culture media and culture media supplements
ATE420945T1 (de) * 2001-02-15 2009-01-15 Centocor Inc Chemisch definiertes medium für kultivierte säugerzellen

Also Published As

Publication number Publication date
US20030175951A1 (en) 2003-09-18
JP2010000094A (ja) 2010-01-07
DE60301510T2 (de) 2006-06-14
CA2417689A1 (en) 2003-09-05
EP1342780A1 (en) 2003-09-10
CN100398640C (zh) 2008-07-02
US7390660B2 (en) 2008-06-24
KR100576589B1 (ko) 2006-05-04
JP2003250533A (ja) 2003-09-09
MXPA03001487A (es) 2005-09-08
JP5191970B2 (ja) 2013-05-08
KR20030074204A (ko) 2003-09-19
DE60301510D1 (de) 2005-10-13
EP1342780B1 (en) 2005-09-07
ATE304047T1 (de) 2005-09-15
JP4476554B2 (ja) 2010-06-09
CA2417689C (en) 2006-05-09
CN1442478A (zh) 2003-09-17
ES2248657T3 (es) 2006-03-16

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