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DK1313740T3 - Prodrugs af imidazopyridinderivater - Google Patents

Prodrugs af imidazopyridinderivater

Info

Publication number
DK1313740T3
DK1313740T3 DK01933769T DK01933769T DK1313740T3 DK 1313740 T3 DK1313740 T3 DK 1313740T3 DK 01933769 T DK01933769 T DK 01933769T DK 01933769 T DK01933769 T DK 01933769T DK 1313740 T3 DK1313740 T3 DK 1313740T3
Authority
DK
Denmark
Prior art keywords
prodrugs
imidazopyridine derivatives
imidazopyridine
derivatives
substituents
Prior art date
Application number
DK01933769T
Other languages
English (en)
Inventor
Wolfgang-Alexander Simon
Stefan Postius
Reinhard Huber
Wolfgang Kromer
Joerg Senn-Bilfinger
Wilm Buhr
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1313740T3 publication Critical patent/DK1313740T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK01933769T 2000-03-29 2001-03-28 Prodrugs af imidazopyridinderivater DK1313740T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29

Publications (1)

Publication Number Publication Date
DK1313740T3 true DK1313740T3 (da) 2006-04-03

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01933769T DK1313740T3 (da) 2000-03-29 2001-03-28 Prodrugs af imidazopyridinderivater

Country Status (25)

Country Link
US (2) US20030125327A1 (da)
EP (1) EP1313740B1 (da)
JP (1) JP2003528878A (da)
KR (1) KR100860627B1 (da)
CN (1) CN1214030C (da)
AT (1) ATE311389T1 (da)
AU (1) AU783633B2 (da)
BR (1) BR0109483A (da)
CA (1) CA2404474A1 (da)
CZ (1) CZ20023194A3 (da)
DE (1) DE60115466T2 (da)
DK (1) DK1313740T3 (da)
EA (1) EA005597B1 (da)
ES (1) ES2253376T3 (da)
HR (1) HRP20020854A2 (da)
HU (1) HUP0302331A2 (da)
IL (2) IL151200A0 (da)
MX (1) MXPA02009551A (da)
NO (1) NO20024662L (da)
NZ (1) NZ520837A (da)
PL (1) PL365116A1 (da)
SI (1) SI1313740T1 (da)
SK (1) SK286850B6 (da)
WO (1) WO2001072756A1 (da)
ZA (1) ZA200207637B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0109542A (pt) * 2000-03-29 2003-06-10 Altana Pharma Ag Derivados de imidazopirina alquilados
MXPA03003706A (es) 2000-10-25 2005-01-25 Altana Pharma Ag Imidazopiridinas polisustituidas, como inhibidores de secrecion gastrica.
US20050020637A1 (en) * 2001-11-19 2005-01-27 Wolfgang-Alexander Simon Agents for the treatment of airway disorders
AU2003206879A1 (en) 2002-02-15 2003-09-04 Altana Pharma Ag Tricyclic n-acyl compounds
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
RS95304A (sr) * 2002-05-07 2006-12-15 Altana Pharma Ag. Nova kombinacija za tretman oboljenja disajnih puteva
RS20050377A (sr) 2002-11-19 2007-11-15 Altana Pharma Ag., 8-supstituisani imidazopiridini
RS20050449A (sr) * 2002-12-20 2007-11-15 Altana Pharma Ag., 8-trialkisiloksi-2-metil-9-fenil-7- okso-7,8,9,10- tetrahidroimidazo /1,2h//1,7/naftiridini
HRP20050790A2 (en) * 2003-02-17 2006-12-31 Altana Pharma Ag New combinations and new use of selected pharmaceutically active compounds
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
RS20050868A (sr) * 2003-05-27 2007-08-03 Altana Pharma Ag., Farmaceutske kombinacije inhibotora protonske pumpe i jedinjenje koje modifikuje gastrointestinalni motilitet
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
CN101027277A (zh) * 2004-07-23 2007-08-29 帝斯曼知识产权资产管理有限公司 (2r,3r)-2-羟基-3-氨基-3-芳基-丙酰胺和(2r,3r)-2-羟基-3-氨基-3-芳基-丙酸烷基酯的制备方法
CA2582256A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
RU2586276C2 (ru) 2009-07-09 2016-06-10 Раквалиа Фарма Инк. Антагонист кислотного насоса для лечения заболеваний, связанных с патологическим нарушением моторики желудочно-кишечного тракта

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
JPH06502659A (ja) * 1991-05-31 1994-03-24 ファイザー インク 免疫抑制剤としてのラパマイシンプロドラッグの使用
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
ES2219890T3 (es) * 1997-03-24 2004-12-01 Altana Pharma Ag Compuestos tetrahidropirido.
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
JP2001526703A (ja) * 1997-05-28 2001-12-18 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 縮合ジヒドロピラン
PT1115725E (pt) * 1998-09-23 2003-06-30 Altana Pharma Ag Tetra-hidropiridoeteres
WO2000026217A1 (en) * 1998-11-03 2000-05-11 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazonaphthyridines
BR0109542A (pt) 2000-03-29 2003-06-10 Altana Pharma Ag Derivados de imidazopirina alquilados

Also Published As

Publication number Publication date
ES2253376T3 (es) 2006-06-01
US7189736B2 (en) 2007-03-13
ATE311389T1 (de) 2005-12-15
SK13852002A3 (sk) 2003-02-04
NZ520837A (en) 2005-01-28
DE60115466D1 (de) 2006-01-05
EA200200875A1 (ru) 2003-04-24
SI1313740T1 (sl) 2006-04-30
US20040198764A1 (en) 2004-10-07
KR20020084262A (ko) 2002-11-04
CA2404474A1 (en) 2001-10-04
HUP0302331A2 (hu) 2003-12-29
WO2001072756A1 (en) 2001-10-04
KR100860627B1 (ko) 2008-09-29
PL365116A1 (en) 2004-12-27
DE60115466T2 (de) 2006-07-20
NO20024662D0 (no) 2002-09-27
NO20024662L (no) 2002-09-27
HRP20020854A2 (en) 2004-12-31
BR0109483A (pt) 2003-06-10
ZA200207637B (en) 2004-04-08
US20030125327A1 (en) 2003-07-03
EP1313740A1 (en) 2003-05-28
IL151200A0 (en) 2003-04-10
CN1214030C (zh) 2005-08-10
EA005597B1 (ru) 2005-04-28
EP1313740B1 (en) 2005-11-30
CZ20023194A3 (cs) 2003-01-15
MXPA02009551A (es) 2004-05-14
JP2003528878A (ja) 2003-09-30
CN1426414A (zh) 2003-06-25
IL151200A (en) 2009-11-18
AU6016601A (en) 2001-10-08
SK286850B6 (sk) 2009-06-05
HK1056175A1 (en) 2004-02-06
AU783633B2 (en) 2005-11-17

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