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DK130646B - Analogous process for the preparation of 17- and / or 21-alkanoyloxy-11beta-chloro-16beta-methylpregna-1,4-diene-3,20-diones. - Google Patents

Analogous process for the preparation of 17- and / or 21-alkanoyloxy-11beta-chloro-16beta-methylpregna-1,4-diene-3,20-diones.

Info

Publication number
DK130646B
DK130646B DK46469A DK46469A DK130646B DK 130646 B DK130646 B DK 130646B DK 46469 A DK46469 A DK 46469A DK 46469 A DK46469 A DK 46469A DK 130646 B DK130646 B DK 130646B
Authority
DK
Denmark
Prior art keywords
16beta
methylpregna
11beta
diones
alkanoyloxy
Prior art date
Application number
DK46469A
Other languages
Danish (da)
Other versions
DK130646C (en
Inventor
G H Phillipps
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK130646B publication Critical patent/DK130646B/en
Application granted granted Critical
Publication of DK130646C publication Critical patent/DK130646C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK46469A 1968-01-29 1969-01-29 Analogous process for the preparation of 17- and / or 21-alkanoyloxy-11beta-chloro-16beta-methylpregna-1,4-diene-3,20-diones. DK130646B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB456968A GB1260464A (en) 1968-01-29 1968-01-29 11beta-HALO-STEROIDS

Publications (2)

Publication Number Publication Date
DK130646B true DK130646B (en) 1975-03-17
DK130646C DK130646C (en) 1975-08-25

Family

ID=9779625

Family Applications (1)

Application Number Title Priority Date Filing Date
DK46469A DK130646B (en) 1968-01-29 1969-01-29 Analogous process for the preparation of 17- and / or 21-alkanoyloxy-11beta-chloro-16beta-methylpregna-1,4-diene-3,20-diones.

Country Status (6)

Country Link
CH (1) CH547789A (en)
DE (1) DE1904324A1 (en)
DK (1) DK130646B (en)
FR (1) FR2000923A1 (en)
GB (1) GB1260464A (en)
NL (1) NL6901341A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591689A (en) * 1969-06-04 1971-07-06 Mead Johnson & Co Progestational composition in oral dosage form

Also Published As

Publication number Publication date
FR2000923A1 (en) 1969-09-19
DK130646C (en) 1975-08-25
GB1260464A (en) 1972-01-19
NL6901341A (en) 1969-07-31
CH547789A (en) 1974-04-11
DE1904324A1 (en) 1969-09-11

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