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DK129291B - Fremgangsmåde til fremstilling af et kimfattigt, flydedygtigt pancreatinpræparat. - Google Patents

Fremgangsmåde til fremstilling af et kimfattigt, flydedygtigt pancreatinpræparat.

Info

Publication number
DK129291B
DK129291B DK362171AA DK362171A DK129291B DK 129291 B DK129291 B DK 129291B DK 362171A A DK362171A A DK 362171AA DK 362171 A DK362171 A DK 362171A DK 129291 B DK129291 B DK 129291B
Authority
DK
Denmark
Prior art keywords
preparation
germ
poor
liquid pancreatin
liquid
Prior art date
Application number
DK362171AA
Other languages
English (en)
Other versions
DK129291C (da
Inventor
H Hess
G Mueller
H Stolte
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK129291B publication Critical patent/DK129291B/da
Application granted granted Critical
Publication of DK129291C publication Critical patent/DK129291C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/94Pancreatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/98Preparation of granular or free-flowing enzyme compositions

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK362171AA 1970-07-23 1971-07-22 Fremgangsmåde til fremstilling af et kimfattigt, flydedygtigt pancreatinpræparat. DK129291B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1117070 1970-07-23

Publications (2)

Publication Number Publication Date
DK129291B true DK129291B (da) 1974-09-23
DK129291C DK129291C (da) 1975-02-10

Family

ID=4370762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK362171AA DK129291B (da) 1970-07-23 1971-07-22 Fremgangsmåde til fremstilling af et kimfattigt, flydedygtigt pancreatinpræparat.

Country Status (10)

Country Link
US (1) US3844891A (da)
AU (1) AU3151071A (da)
BE (1) BE770323A (da)
CA (1) CA957942A (da)
DE (1) DE2135025A1 (da)
DK (1) DK129291B (da)
FR (1) FR2103164A5 (da)
GB (1) GB1342409A (da)
NL (1) NL7110132A (da)
ZA (1) ZA714795B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2512746C3 (de) * 1975-03-22 1980-04-24 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
FR2422720A2 (fr) * 1977-04-26 1979-11-09 Elf Aquitaine Separation et purification de proteines par chromatographie
DE2923279C2 (de) * 1979-06-08 1987-07-09 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von Pankreatin-Pellets und diese enthaltende Arzneimittel
CA2198317C (en) * 1997-02-24 2003-01-07 Mouhsine El Abboudi Method for preparing pancreatin which contains low amounts of residual organic solvent and product thereof
KR100367659B1 (ko) * 2000-05-08 2003-01-14 주식회사 바이넥스 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US7153504B2 (en) * 2004-07-30 2006-12-26 Can Technologies, Inc. Stabilized pancreas product
US8293229B2 (en) 2007-02-20 2012-10-23 Aptalis Pharma Limited Methods of producing stable pancreatic enzyme compositions
DE102007044100A1 (de) * 2007-09-14 2009-03-19 Nordmark Arzneimittel Gmbh & Co. Kg Verfahren zur Reduktion der Viren- und Mikroorganismen-Belastung feststoffhaltiger biologischer Extrakte
DE202008003806U1 (de) 2007-09-14 2009-02-12 Nordmark Arzneimittel Gmbh & Co. Kg Extrakt für die Herstellung von pharmazeutischen Therapeutika und dessen Verwendung als Nahrungs- oder Lebensmittel oder Nahrungsergänzungsmittel
US10087493B2 (en) * 2008-03-07 2018-10-02 Aptalis Pharma Canada Ulc Method for detecting infectious parvovirus in pharmaceutical preparations
ATE541591T1 (de) * 2008-11-03 2012-02-15 Nordmark Arzneimittel Gmbh & Co Kg Verfahren zur verringerung der viralen und mikrobiellen belastung von pankreatin
EA029101B1 (ru) 2010-10-01 2018-02-28 Апталис Фарма Лимитид Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием
EP2987499B1 (en) 2011-08-08 2019-05-08 Allergan Pharmaceuticals International Limited Method for dissolution testing of solid compositions containing digestive enzymes
CA2920844A1 (en) 2013-08-09 2015-02-12 Allergan Pharmaceuticals International Limited Digestive enzyme composition suitable for enteral administration
JP2017519490A (ja) 2014-06-19 2017-07-20 アプタリス ファルマ リミテッド 膵臓抽出物からのウイルス汚染の除去方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2503313A (en) * 1947-04-14 1950-04-11 Levin Ezra Production of dried, defatted enzymatic material
US2922749A (en) * 1953-07-17 1960-01-26 Miles Lab Enzymes

Also Published As

Publication number Publication date
GB1342409A (en) 1974-01-03
DE2135025A1 (de) 1972-01-27
ZA714795B (en) 1972-04-26
AU3151071A (en) 1973-01-25
DK129291C (da) 1975-02-10
NL7110132A (da) 1972-01-25
US3844891A (en) 1974-10-29
FR2103164A5 (da) 1972-04-07
BE770323A (fr) 1972-01-24
CA957942A (en) 1974-11-19

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