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DK1268469T3 - N-(heterocyklyl)-benzen- eller -pyridin-sulfonamider som antitrombotiske midler og antikoagulationsmidler - Google Patents

N-(heterocyklyl)-benzen- eller -pyridin-sulfonamider som antitrombotiske midler og antikoagulationsmidler

Info

Publication number
DK1268469T3
DK1268469T3 DK01919537T DK01919537T DK1268469T3 DK 1268469 T3 DK1268469 T3 DK 1268469T3 DK 01919537 T DK01919537 T DK 01919537T DK 01919537 T DK01919537 T DK 01919537T DK 1268469 T3 DK1268469 T3 DK 1268469T3
Authority
DK
Denmark
Prior art keywords
anticoagulants
heterocyclyl
benzene
antithrombotic agents
pyridine sulfonamides
Prior art date
Application number
DK01919537T
Other languages
Danish (da)
English (en)
Inventor
Jean-Michel Altenburger
Gerard Cremer
Gilbert Lassalle
Mostafa Matrougui
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1268469T3 publication Critical patent/DK1268469T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK01919537T 2000-03-23 2001-03-22 N-(heterocyklyl)-benzen- eller -pyridin-sulfonamider som antitrombotiske midler og antikoagulationsmidler DK1268469T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0003724A FR2806722B1 (fr) 2000-03-23 2000-03-23 Derives de n-(heterocyclylbutyl) benzene-ou pyridine sulfonamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
DK1268469T3 true DK1268469T3 (da) 2004-10-11

Family

ID=8848428

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01919537T DK1268469T3 (da) 2000-03-23 2001-03-22 N-(heterocyklyl)-benzen- eller -pyridin-sulfonamider som antitrombotiske midler og antikoagulationsmidler

Country Status (35)

Country Link
US (1) US6680329B2 (hr)
EP (1) EP1268469B1 (hr)
JP (1) JP2003528098A (hr)
KR (1) KR100791693B1 (hr)
CN (1) CN1183128C (hr)
AR (1) AR029900A1 (hr)
AT (1) ATE269325T1 (hr)
AU (2) AU4661701A (hr)
BG (1) BG65863B1 (hr)
BR (1) BR0109385A (hr)
CA (1) CA2401637C (hr)
DE (1) DE60103868T2 (hr)
DK (1) DK1268469T3 (hr)
EA (1) EA004986B1 (hr)
EE (1) EE05084B1 (hr)
ES (1) ES2222358T3 (hr)
FR (1) FR2806722B1 (hr)
HK (1) HK1051537A1 (hr)
HR (1) HRP20020762B1 (hr)
HU (1) HUP0300695A2 (hr)
IL (2) IL151619A0 (hr)
IS (1) IS2304B (hr)
ME (1) MEP17408A (hr)
MX (1) MXPA02009276A (hr)
NO (1) NO324835B1 (hr)
PL (1) PL204660B1 (hr)
PT (1) PT1268469E (hr)
RS (1) RS50370B (hr)
SI (1) SI1268469T1 (hr)
SK (1) SK286687B6 (hr)
TR (1) TR200402343T4 (hr)
TW (1) TWI290141B (hr)
UA (1) UA71667C2 (hr)
WO (1) WO2001070736A1 (hr)
ZA (1) ZA200206996B (hr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
CA2508165C (en) * 2002-12-06 2014-05-06 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
EP1739077A4 (en) * 2004-04-19 2008-04-16 Daiso Co Ltd PROCESS FOR THE PRODUCTION OF NON-NATURAL AMINO ACIDS AND INTERMEDIATES THEREFOR
US7750162B2 (en) 2004-04-19 2010-07-06 Daiso Co., Ltd. Process for preparation of nonnatural amino acid and intermediate thereof
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
EP2276731A1 (en) * 2008-04-09 2011-01-26 Boehringer Ingelheim International GmbH 2-sulfonylamino-4-heteroaryl butyramide antagonists of ccr10
CA2725140A1 (en) * 2008-05-22 2009-11-26 Boehringer Ingelheim International Gmbh Alpha-substituted n-sulfonyl gylcine amides antagonists of ccr10, compositions containing the same and methods for using them
MX345259B (es) * 2010-01-28 2017-01-23 The Medicines Company (Leipzig) Gmbh Inhibidores de serina proteasas similares a tripsina, y su preparación y uso.
FR2981071B1 (fr) * 2011-10-10 2014-02-07 Centre Nat Rech Scient Synthese versatile et stereospecifique d'acides amines gamma,delta-insatures par la reaction de wittig

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727410B1 (fr) * 1994-11-25 1996-12-20 Synthelabo Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese
FR2728570B1 (fr) * 1994-12-23 1997-04-11 Synthelabo Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique
FR2756285B1 (fr) * 1996-11-22 1998-12-18 Synthelabo Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique
FR2756220B1 (fr) * 1996-11-27 1998-12-24 Lorraine Laminage Roue pour vehicule terrestre a moteur
FR2771094B1 (fr) * 1997-11-19 2000-02-04 Synthelabo Derives de piperidine-2-carboxylate, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
FR2806722B1 (fr) 2002-05-17
AR029900A1 (es) 2003-07-23
JP2003528098A (ja) 2003-09-24
PL204660B1 (pl) 2010-01-29
CN1426407A (zh) 2003-06-25
EE200200540A (et) 2004-04-15
BG65863B1 (bg) 2010-03-31
IS2304B (is) 2007-10-15
SK13512002A3 (sk) 2003-03-04
SK286687B6 (sk) 2009-03-05
YU67002A (sh) 2005-07-19
EP1268469B1 (fr) 2004-06-16
US6680329B2 (en) 2004-01-20
DE60103868D1 (de) 2004-07-22
DE60103868T2 (de) 2005-06-09
MXPA02009276A (es) 2003-05-23
FR2806722A1 (fr) 2001-09-28
EA200200838A1 (ru) 2003-04-24
EE05084B1 (et) 2008-10-15
ATE269325T1 (de) 2004-07-15
AU4661701A (en) 2001-10-03
CN1183128C (zh) 2005-01-05
CA2401637C (en) 2009-11-10
ES2222358T3 (es) 2005-02-01
EP1268469A1 (fr) 2003-01-02
SI1268469T1 (en) 2004-10-31
NO20024496D0 (no) 2002-09-19
TWI290141B (en) 2007-11-21
KR20020081476A (ko) 2002-10-26
BG107130A (bg) 2003-06-30
CA2401637A1 (en) 2001-09-27
MEP17408A (hr) 2010-06-10
BR0109385A (pt) 2003-06-03
HRP20020762B1 (en) 2005-02-28
RS50370B (sr) 2009-11-10
HK1051537A1 (en) 2003-08-08
IL151619A (en) 2009-05-04
WO2001070736A1 (fr) 2001-09-27
AU2001246617B2 (en) 2006-03-02
PL364988A1 (en) 2004-12-27
IS6535A (is) 2002-08-30
TR200402343T4 (tr) 2004-12-21
NO20024496L (no) 2002-11-22
US20030207920A1 (en) 2003-11-06
EA004986B1 (ru) 2004-10-28
HRP20020762A2 (en) 2003-12-31
NO324835B1 (no) 2007-12-17
ZA200206996B (en) 2003-09-01
HUP0300695A2 (hu) 2003-07-28
KR100791693B1 (ko) 2008-01-03
PT1268469E (pt) 2004-10-29
IL151619A0 (en) 2003-04-10
UA71667C2 (uk) 2004-12-15

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