DK124089D0 - Heterocykliske derivater - Google Patents
Heterocykliske derivaterInfo
- Publication number
- DK124089D0 DK124089D0 DK124089A DK124089A DK124089D0 DK 124089 D0 DK124089 D0 DK 124089D0 DK 124089 A DK124089 A DK 124089A DK 124089 A DK124089 A DK 124089A DK 124089 D0 DK124089 D0 DK 124089D0
- Authority
- DK
- Denmark
- Prior art keywords
- group
- hydrogen
- alkyl
- het
- hetero
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/42—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having etherified hydroxy groups and at least two amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888806210A GB8806210D0 (en) | 1988-03-16 | 1988-03-16 | Novel compounds |
GB888823562A GB8823562D0 (en) | 1988-10-07 | 1988-10-07 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DK124089D0 true DK124089D0 (da) | 1989-03-14 |
DK124089A DK124089A (da) | 1989-09-17 |
Family
ID=26293641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK124089A DK124089A (da) | 1988-03-16 | 1989-03-14 | Heterocykliske derivater |
Country Status (14)
Country | Link |
---|---|
US (1) | US4999359A (da) |
EP (1) | EP0333427B1 (da) |
JP (1) | JPH02101062A (da) |
KR (1) | KR890014478A (da) |
AT (1) | ATE126802T1 (da) |
AU (1) | AU616488B2 (da) |
CA (1) | CA1336909C (da) |
DE (1) | DE68923891T2 (da) |
DK (1) | DK124089A (da) |
ES (1) | ES2075849T3 (da) |
GR (1) | GR3017213T3 (da) |
IE (1) | IE67334B1 (da) |
NZ (1) | NZ228331A (da) |
PT (1) | PT90001B (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8824400D0 (en) * | 1988-10-18 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
DE3935371A1 (de) * | 1988-12-23 | 1990-07-05 | Merck Patent Gmbh | Stickstoffhaltige ringverbindungen |
GB8926560D0 (en) * | 1989-11-24 | 1990-01-17 | Zambeletti Spa L | Pharmaceuticals |
CA2069423A1 (en) * | 1989-11-24 | 1991-05-25 | Roberto Colle | Azacyclic derivatives |
WO1991017116A1 (en) * | 1990-04-28 | 1991-11-14 | Dr. Lo. Zambeletti S.P.A. | Novel 1-(2h-1-oxo-3,4-dihydronaphtyl-6)-acetyl-piperidines, process for their preparation and therapeutic use |
GB9104839D0 (en) * | 1991-03-07 | 1991-04-17 | Zambeletti Spa L | Novel compounds |
WO1992018115A1 (en) * | 1991-04-18 | 1992-10-29 | Dr Lo Zambeletti S.P.A. | Use of heterocyclic compounds for the treatment of inflammatory pain |
US5763445A (en) | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
BR9810706A (pt) * | 1997-07-14 | 2000-08-08 | Adolor Corp | Processo para a prevenção ou tratamento do prurido em um mamìfero em necessidade de tal prevenção ou tratamento |
US5760023A (en) * | 1997-07-14 | 1998-06-02 | Adolor Corporation | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith |
US6645980B1 (en) | 2000-05-25 | 2003-11-11 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US6677332B1 (en) | 1999-05-25 | 2004-01-13 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US6635661B2 (en) | 2000-05-25 | 2003-10-21 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US7361666B2 (en) | 1999-05-25 | 2008-04-22 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US6476046B1 (en) | 2000-12-04 | 2002-11-05 | Sepracor, Inc. | Diazabicyclo[4.3.0]nonanes, and methods of use thereof |
CL2007002097A1 (es) | 2006-07-20 | 2008-01-18 | Smithkline Beecham Corp | Compuestos derivados de pirrolidina o morfolina antagonistas de urotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar insuficiencia cardiaca congestiva, insuficiencia cardiaca isquemica, angina, isquemia del miocardio, vejiga hiperactiva, asma y/o copd, entre otras. |
UY30892A1 (es) | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
KR101420484B1 (ko) | 2009-01-30 | 2014-07-28 | 글락소스미스클라인 엘엘씨 | 결정질 n-{(1s)-2-아미노-1-[(3-플루오로페닐)메틸]에틸}-5-클로로-4-(4-클로로-1-메틸-1h-피라졸-5-일)-2-티오펜카르복스아미드 히드로클로라이드 |
CN111560025A (zh) | 2009-12-04 | 2020-08-21 | 桑诺维恩药品公司 | 多环化合物及其使用方法 |
SG10202100751YA (en) | 2016-07-29 | 2021-03-30 | Sunovion Pharmaceuticals Inc | Compounds and compositions and uses thereof |
EA201990400A1 (ru) | 2016-07-29 | 2019-07-31 | Суновион Фармасьютикалз, Инк. | Соединения и композиции и их применение |
JP7177053B2 (ja) * | 2016-12-02 | 2022-11-22 | フラウンホファー ゲセルシャフト ツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー.ファオ. | 歯周炎の治療に使用するための細菌グルタミニルシクラーゼ及びその阻害剤 |
IL268694B2 (en) | 2017-02-16 | 2023-10-01 | Sunovion Pharmaceuticals Inc | Treatment of schizophrenia |
SG11202000669VA (en) | 2017-08-02 | 2020-02-27 | Sunovion Pharmaceuticals Inc | Isochroman compounds and uses thereof |
CN112135827B (zh) | 2018-02-16 | 2024-01-12 | 赛诺维信制药公司 | 盐、晶型及其制备方法 |
CA3130849A1 (en) | 2019-03-14 | 2020-09-17 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
JP2023523569A (ja) | 2020-04-14 | 2023-06-06 | サノビオン ファーマシューティカルズ インク | 神経学的および精神障害の治療方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
GB8618188D0 (en) * | 1986-07-25 | 1986-09-03 | Ici Plc | Diamine compounds |
DE3766335D1 (de) * | 1986-09-17 | 1991-01-03 | Zambeletti Spa L | N-1-acylierte-(1-(phenyl- oder benzyl-))-1,2-aethylendiamine. |
DE3935371A1 (de) * | 1988-12-23 | 1990-07-05 | Merck Patent Gmbh | Stickstoffhaltige ringverbindungen |
-
1989
- 1989-03-14 PT PT90001A patent/PT90001B/pt not_active IP Right Cessation
- 1989-03-14 EP EP89302486A patent/EP0333427B1/en not_active Expired - Lifetime
- 1989-03-14 ES ES89302486T patent/ES2075849T3/es not_active Expired - Lifetime
- 1989-03-14 US US07/323,617 patent/US4999359A/en not_active Expired - Fee Related
- 1989-03-14 DE DE68923891T patent/DE68923891T2/de not_active Expired - Fee Related
- 1989-03-14 AU AU31315/89A patent/AU616488B2/en not_active Ceased
- 1989-03-14 DK DK124089A patent/DK124089A/da not_active Application Discontinuation
- 1989-03-14 CA CA000593618A patent/CA1336909C/en not_active Expired - Fee Related
- 1989-03-14 NZ NZ228331A patent/NZ228331A/xx unknown
- 1989-03-14 IE IE81689A patent/IE67334B1/en not_active IP Right Cessation
- 1989-03-14 AT AT89302486T patent/ATE126802T1/de not_active IP Right Cessation
- 1989-03-15 KR KR1019890003299A patent/KR890014478A/ko not_active Application Discontinuation
- 1989-03-16 JP JP1062376A patent/JPH02101062A/ja active Pending
-
1995
- 1995-08-24 GR GR950402211T patent/GR3017213T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE126802T1 (de) | 1995-09-15 |
IE890816L (en) | 1989-09-16 |
JPH02101062A (ja) | 1990-04-12 |
IE67334B1 (en) | 1996-03-20 |
DE68923891T2 (de) | 1996-02-22 |
AU616488B2 (en) | 1991-10-31 |
ES2075849T3 (es) | 1995-10-16 |
AU3131589A (en) | 1989-09-21 |
PT90001A (pt) | 1989-11-10 |
EP0333427B1 (en) | 1995-08-23 |
CA1336909C (en) | 1995-09-05 |
KR890014478A (ko) | 1989-10-23 |
DE68923891D1 (de) | 1995-09-28 |
PT90001B (pt) | 1994-06-30 |
GR3017213T3 (en) | 1995-11-30 |
US4999359A (en) | 1991-03-12 |
DK124089A (da) | 1989-09-17 |
EP0333427A1 (en) | 1989-09-20 |
NZ228331A (en) | 1991-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |