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DK121174B - Analogifremgangsmåde til fremstilling af N-substituerede lactamer. - Google Patents

Analogifremgangsmåde til fremstilling af N-substituerede lactamer.

Info

Publication number
DK121174B
DK121174B DK403065AA DK403065A DK121174B DK 121174 B DK121174 B DK 121174B DK 403065A A DK403065A A DK 403065AA DK 403065 A DK403065 A DK 403065A DK 121174 B DK121174 B DK 121174B
Authority
DK
Denmark
Prior art keywords
preparation
analogous process
substituted lactams
lactams
substituted
Prior art date
Application number
DK403065AA
Other languages
English (en)
Inventor
H Morren
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of DK121174B publication Critical patent/DK121174B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DK403065AA 1964-08-06 1965-08-05 Analogifremgangsmåde til fremstilling af N-substituerede lactamer. DK121174B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB32037/64A GB1039113A (en) 1964-08-06 1964-08-06 New n-substituted lactams

Publications (1)

Publication Number Publication Date
DK121174B true DK121174B (da) 1971-09-20

Family

ID=10332139

Family Applications (1)

Application Number Title Priority Date Filing Date
DK403065AA DK121174B (da) 1964-08-06 1965-08-05 Analogifremgangsmåde til fremstilling af N-substituerede lactamer.

Country Status (15)

Country Link
US (1) US3459738A (da)
AT (2) AT258260B (da)
BE (1) BE667906A (da)
CH (1) CH436304A (da)
CY (1) CY727A (da)
DE (1) DE1620608C3 (da)
DK (1) DK121174B (da)
ES (1) ES316156A1 (da)
FI (1) FI45446C (da)
FR (2) FR1478349A (da)
GB (1) GB1039113A (da)
IL (1) IL24082A (da)
IT (1) IT1052776B (da)
NL (1) NL148313B (da)
SE (1) SE308526B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK156055B (da) * 1975-08-13 1989-06-19 Isf Spa Analogifremgangsmaade til fremstilling af pyrrolidin-2-onderivater

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1309692A (en) * 1970-02-13 1973-03-14 Ucb Sa N-substituted lactams
FR2059985A1 (en) * 1969-08-29 1971-06-11 Synthelabo 4-benzyl piperidine 2,6-dione derivs
US4081456A (en) * 1973-02-28 1978-03-28 Mobil Oil Corporation Bis-lactam derivatives
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
US4069336A (en) * 1976-02-25 1978-01-17 Chemisches Laboratorium Fritz-Walter Lange Gmbh & Co Kg (2-oxo-pyrrolidines)-acetic hydrazides
GB1583871A (en) * 1976-10-19 1981-02-04 Ucb Sa Anti-aggregants
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
GB1582351A (en) * 1977-02-10 1981-01-07 Ucb Sa Disubstituted ureas and thioureas
DE2757680A1 (de) * 1977-12-23 1979-06-28 Troponwerke Gmbh & Co Kg Neue 2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA1115212A (en) 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
ATE27T1 (de) 1978-05-08 1981-04-15 Ucb Sa Lactam-n-essigsaeuren und ihre amide, verfahren zu ihrer herstellung und heilmittel, die sie enthalten
DE2924011C2 (de) 1979-06-13 1982-04-08 A. Nattermann & Cie GmbH, 5000 Köln Pyrrolidin-(2)-on-(1)-ylessigsäure-2,6,-dimethylanilid, Verfahren zur Herstellung und Arzneimittel, welche diese Verbindung enthalten
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
EP0089900B1 (en) * 1982-03-24 1985-12-27 Prodes S.A. New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
US4525476A (en) * 1983-05-26 1985-06-25 Warner-Lambert Company N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators
DE3326724A1 (de) * 1983-07-25 1985-02-07 Boehringer Ingelheim KG, 6507 Ingelheim In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
FI83510C (fi) * 1985-02-22 1991-07-25 Ciba Geigy Ag Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara bi-2h- pyrroli(di)ndioner.
PH23078A (en) * 1986-01-30 1989-04-10 Ciba Geigy Ag Substituted pyrrolidinones
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa
US4990513A (en) * 1987-02-06 1991-02-05 S O "Pharmachim" Antihypoxic drug and method of its application
US4985428A (en) * 1987-05-20 1991-01-15 Zambon Group S.P.A. Isoxazoles with nootropic activity
JPS6422883A (en) * 1987-07-17 1989-01-25 Sanwa Kagaku Kenkyusho Co 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient
JP2660201B2 (ja) * 1988-08-05 1997-10-08 塩野義製薬株式会社 新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬
FI102748B (fi) * 1992-06-19 1999-02-15 Daiichi Seiyaku Co Menetelmä N-(2,6-dialkyylifenyyli)-2-(2-okso-1-pyrrolidinyyli)asetamid ijohdannaisen valmistamiseksi
CN1041630C (zh) * 1994-01-13 1999-01-13 北京大学 合成α-吡咯烷酮乙酰胺的方法
US5912189A (en) * 1998-05-12 1999-06-15 The Lubrizol Corporation Compositions containing reaction product of a cyclic compound containing both a nitrogen atom and a carbonyl group, an aldehyde or ketone, and an etheramine
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
ATE431142T1 (de) * 2000-12-28 2009-05-15 Hamilton Pharmaceuticals Inc Arzneimittel zur behandlung und vermeidung neurogener schmerzen
CL2009000478A1 (es) 2008-02-29 2009-08-07 Biolab Sanus Farmaceutica Ltda Composicion farmaceutica que comprende piracetam o una sal del mismo, l-carnitina y un vehiculo; proceso de preparacion de la composicion; y su uso para el tratamiento y/o prevencion de trastornos mitocondriales relacionados con efectos colaterales inducidos por farmacos, tal como enfermedad de alzheimer o mal de parkinson.
JP5917148B2 (ja) 2008-10-16 2016-05-11 ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ 認知機能を改善するための方法および組成物
PL389364A1 (pl) 2009-10-23 2011-04-26 Uniwersytet Jagielloński Nowe zastosowanie pochodnych 2-pirolidonu
CA2789014C (en) 2010-02-09 2019-01-15 Michela Gallagher Methods and compositions for improving cognitive function
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
US11160785B2 (en) 2013-03-15 2021-11-02 Agenebio Inc. Methods and compositions for improving cognitive function
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
IL279202B2 (en) 2014-01-21 2023-09-01 Janssen Pharmaceutica Nv Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use
SG11201605742TA (en) 2014-01-21 2016-08-30 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
DK3554490T3 (da) 2016-12-16 2022-02-28 Idorsia Pharmaceuticals Ltd Farmaceutisk kombination omfattende en calciumkanalblokker type T
EA037205B1 (ru) * 2019-05-20 2021-02-19 Дмитрий Сергеевич Валуев Способ получения 2-(2-оксопирролидин-1-ил)-n-фенилацетамида
US20240132513A1 (en) 2022-08-19 2024-04-25 Agenebio, Inc. Benzazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE592979A (da) * 1959-07-14
US3185678A (en) * 1961-08-04 1965-05-25 Colgate Palmolive Co Polymethyleniminoalkylamides
US3250784A (en) * 1963-12-23 1966-05-10 Gen Aniline & Film Corp Pyrrolidonyl-gamma-butyramide and process of preparing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK156055B (da) * 1975-08-13 1989-06-19 Isf Spa Analogifremgangsmaade til fremstilling af pyrrolidin-2-onderivater

Also Published As

Publication number Publication date
AT258260B (de) 1967-11-10
FI45446C (fi) 1972-06-12
GB1039113A (en) 1966-08-17
NL6509994A (da) 1966-02-07
DE1620608A1 (de) 1970-04-30
IL24082A (en) 1969-02-27
FR1478349A (fr) 1967-04-28
CH436304A (fr) 1967-05-31
SE308526B (da) 1969-02-17
DE1620608B2 (de) 1975-01-30
ES316156A1 (es) 1965-11-16
NL148313B (nl) 1976-01-15
DE1620608C3 (de) 1975-09-25
US3459738A (en) 1969-08-05
BE667906A (da) 1966-02-07
IT1052776B (it) 1981-07-20
AT261599B (de) 1968-05-10
CY727A (en) 1974-03-01
FI45446B (da) 1972-02-29
FR7119M (da) 1969-07-21

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