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DK1177178T3 - Heterocyclisk substituerede benzimidazoler, deres fremstilling og anvendelse - Google Patents

Heterocyclisk substituerede benzimidazoler, deres fremstilling og anvendelse

Info

Publication number
DK1177178T3
DK1177178T3 DK00927088T DK00927088T DK1177178T3 DK 1177178 T3 DK1177178 T3 DK 1177178T3 DK 00927088 T DK00927088 T DK 00927088T DK 00927088 T DK00927088 T DK 00927088T DK 1177178 T3 DK1177178 T3 DK 1177178T3
Authority
DK
Denmark
Prior art keywords
preparation
heterocyclic substituted
substituted benzimidazoles
benzimidazoles
heterocyclic
Prior art date
Application number
DK00927088T
Other languages
English (en)
Inventor
Michael Kock
Wilfried Lubisch
Thomas Hoeger
Roland Grandel
Uta Holzenkamp
Sabine Schult
Reinhold Mueller
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Application granted granted Critical
Publication of DK1177178T3 publication Critical patent/DK1177178T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DK00927088T 1999-05-07 2000-04-27 Heterocyclisk substituerede benzimidazoler, deres fremstilling og anvendelse DK1177178T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19920936A DE19920936A1 (de) 1999-05-07 1999-05-07 Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung
PCT/EP2000/003813 WO2000068206A1 (de) 1999-05-07 2000-04-27 Heterozyklisch substituierte benzimidazole, deren herstellung und anwendung
EP00927088A EP1177178B1 (de) 1999-05-07 2000-04-27 Heterozyklisch substituierte benzimidazole, deren herstellung und anwendung

Publications (1)

Publication Number Publication Date
DK1177178T3 true DK1177178T3 (da) 2005-05-02

Family

ID=7907219

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00927088T DK1177178T3 (da) 1999-05-07 2000-04-27 Heterocyclisk substituerede benzimidazoler, deres fremstilling og anvendelse

Country Status (27)

Country Link
US (1) US6696437B1 (da)
EP (1) EP1177178B1 (da)
JP (1) JP4004737B2 (da)
KR (1) KR20010112477A (da)
CN (1) CN1353695A (da)
AR (1) AR029161A1 (da)
AT (1) ATE286029T1 (da)
AU (1) AU4558400A (da)
BG (1) BG106035A (da)
BR (1) BR0010342A (da)
CA (1) CA2371645C (da)
CO (1) CO5170517A1 (da)
DE (2) DE19920936A1 (da)
DK (1) DK1177178T3 (da)
ES (1) ES2235869T3 (da)
HK (1) HK1046281A1 (da)
HU (1) HUP0202970A2 (da)
IL (1) IL146147A0 (da)
MY (1) MY122771A (da)
NO (1) NO20015362L (da)
PL (1) PL351558A1 (da)
PT (1) PT1177178E (da)
SK (1) SK15962001A3 (da)
TR (1) TR200103221T2 (da)
UA (1) UA68436C2 (da)
WO (1) WO2000068206A1 (da)
ZA (1) ZA200108609B (da)

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AU714873B2 (en) * 1995-08-02 2000-01-13 Newcastle University Ventures Limited Benzimidazole compounds
CA2258728C (en) * 1996-06-19 2011-09-27 Rhone Poulenc Rorer Limited Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
CZ20011546A3 (cs) * 1998-11-03 2001-08-15 Basf Aktiengesellschaft Derivát substituovaného 2-fenylbenzimidazolu, způsob jeho přípravy a jeho použití
BR9915381A (pt) * 1998-11-17 2001-08-14 Basf Ag Uso de um composto, e, composto
CZ300148B6 (cs) * 1998-11-27 2009-02-25 Abbott Gmbh & Co. Kg Derivát substituovaného benzimidazolu, zpusob jeho prípravy a jeho použití

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JP4004737B2 (ja) 2007-11-07
PT1177178E (pt) 2005-05-31
DE19920936A1 (de) 2000-11-09
ZA200108609B (en) 2002-10-21
ES2235869T3 (es) 2005-07-16
NO20015362D0 (no) 2001-11-02
MY122771A (en) 2006-05-31
EP1177178A1 (de) 2002-02-06
CN1353695A (zh) 2002-06-12
DE50009118D1 (de) 2005-02-03
HK1046281A1 (zh) 2003-01-03
CA2371645C (en) 2007-04-17
AU4558400A (en) 2000-11-21
ATE286029T1 (de) 2005-01-15
SK15962001A3 (sk) 2002-06-04
CO5170517A1 (es) 2002-06-27
PL351558A1 (en) 2003-05-05
TR200103221T2 (tr) 2002-04-22
US6696437B1 (en) 2004-02-24
AR029161A1 (es) 2003-06-18
IL146147A0 (en) 2002-07-25
WO2000068206A1 (de) 2000-11-16
BR0010342A (pt) 2002-05-28
UA68436C2 (en) 2004-08-16
CA2371645A1 (en) 2000-11-16
KR20010112477A (ko) 2001-12-20
BG106035A (en) 2002-06-28
EP1177178B1 (de) 2004-12-29
JP2002544199A (ja) 2002-12-24
NO20015362L (no) 2001-11-02
HUP0202970A2 (hu) 2002-12-28

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