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DK1163208T3 - Caspaseinhibitorer og anvendelser deraf - Google Patents

Caspaseinhibitorer og anvendelser deraf

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Publication number
DK1163208T3
DK1163208T3 DK00957311T DK00957311T DK1163208T3 DK 1163208 T3 DK1163208 T3 DK 1163208T3 DK 00957311 T DK00957311 T DK 00957311T DK 00957311 T DK00957311 T DK 00957311T DK 1163208 T3 DK1163208 T3 DK 1163208T3
Authority
DK
Denmark
Prior art keywords
compounds
caspase
pdat
hil
caspase inhibitors
Prior art date
Application number
DK00957311T
Other languages
English (en)
Inventor
Julian Golec
Paul Charifson
Guy Brenchley
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Application granted granted Critical
Publication of DK1163208T3 publication Critical patent/DK1163208T3/da

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
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DK00957311T 1999-08-06 2000-08-04 Caspaseinhibitorer og anvendelser deraf DK1163208T3 (da)

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PT2399915E (pt) 2004-03-12 2015-03-30 Vertex Pharma Processo e intermediários para a preparação de inibidores de caspase de acetal de ácido aspártico
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Publication number Publication date
EP1163208B1 (en) 2004-05-12
PT1163208E (pt) 2004-08-31
US20020132833A1 (en) 2002-09-19
EP1163208A2 (en) 2001-12-19
DE60010675D1 (de) 2004-06-17
US6632962B2 (en) 2003-10-14
DE60010675T2 (de) 2005-06-16
ATE266623T1 (de) 2004-05-15
TWI281910B (en) 2007-06-01
ES2219381T3 (es) 2004-12-01
EP1163208A4 (en) 2002-07-03
WO2001010383A3 (en) 2001-09-07
WO2001010383A2 (en) 2001-02-15
AU6894800A (en) 2001-03-05
JP2003506389A (ja) 2003-02-18

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