DK1128829T3 - Kombination af riluzol og alfa-tocopherol - Google Patents
Kombination af riluzol og alfa-tocopherolInfo
- Publication number
- DK1128829T3 DK1128829T3 DK99972101T DK99972101T DK1128829T3 DK 1128829 T3 DK1128829 T3 DK 1128829T3 DK 99972101 T DK99972101 T DK 99972101T DK 99972101 T DK99972101 T DK 99972101T DK 1128829 T3 DK1128829 T3 DK 1128829T3
- Authority
- DK
- Denmark
- Prior art keywords
- combination
- riluzole
- tocopherol
- alpha
- benzothiazole
- Prior art date
Links
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 4
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 3
- 229940087168 alpha tocopherol Drugs 0.000 title abstract 2
- 229960004181 riluzole Drugs 0.000 title abstract 2
- 229960000984 tocofersolan Drugs 0.000 title abstract 2
- 239000002076 α-tocopherol Substances 0.000 title abstract 2
- 235000004835 α-tocopherol Nutrition 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Pyrane Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9814250A FR2785808B1 (fr) | 1998-11-13 | 1998-11-13 | Association riluzole et alpha-tocopherol |
| PCT/FR1999/002753 WO2000028992A1 (fr) | 1998-11-13 | 1999-11-09 | Association riluzole et alpha-tocopherol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1128829T3 true DK1128829T3 (da) | 2005-08-29 |
Family
ID=9532674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99972101T DK1128829T3 (da) | 1998-11-13 | 1999-11-09 | Kombination af riluzol og alfa-tocopherol |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6642262B2 (da) |
| EP (1) | EP1128829B1 (da) |
| JP (1) | JP4693241B2 (da) |
| KR (1) | KR100641472B1 (da) |
| CN (1) | CN1177587C (da) |
| AT (1) | ATE295168T1 (da) |
| AU (1) | AU776242B2 (da) |
| BR (1) | BR9915292A (da) |
| CA (1) | CA2350671C (da) |
| CZ (1) | CZ298808B6 (da) |
| DE (1) | DE69925301T2 (da) |
| DK (1) | DK1128829T3 (da) |
| EA (1) | EA003671B1 (da) |
| ES (1) | ES2239858T3 (da) |
| FR (1) | FR2785808B1 (da) |
| HK (1) | HK1041220B (da) |
| HU (1) | HU226067B1 (da) |
| IL (1) | IL142708A0 (da) |
| NO (1) | NO328349B1 (da) |
| PT (1) | PT1128829E (da) |
| TR (1) | TR200101346T2 (da) |
| WO (1) | WO2000028992A1 (da) |
| ZA (1) | ZA200103810B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2786101B1 (fr) * | 1998-11-24 | 2002-07-05 | Aventis Laboratoire | Utilisation de la nicergoline dans le traitement de la spasticite |
| WO2007046347A1 (ja) * | 2005-10-18 | 2007-04-26 | Ono Pharmaceutical Co., Ltd. | 筋萎縮性側索硬化症患者の運動神経保護用医薬 |
| US20070099156A1 (en) * | 2005-10-28 | 2007-05-03 | Jeff Wagner | Self-etching dental primer compositions and methods and systems utilizing such compositions |
| FR2957077B1 (fr) * | 2010-03-02 | 2012-04-13 | Univ Dauvergne Clermont I | Utilisation du riluzole pour traiter ou prevenir les effets indesirables d'agents anti-cancereux |
| WO2014145776A2 (en) * | 2013-03-15 | 2014-09-18 | Baylor College Of Medicine | Msp and its receptors in the therapy of amyotrophic lateral sclerosis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
| US5843641A (en) * | 1993-02-26 | 1998-12-01 | Massachusetts Institute Of Technology | Methods for the daignosis, of familial amyotrophic lateral sclerosis |
| US6380252B1 (en) * | 1996-07-05 | 2002-04-30 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1 |
| US5780489A (en) * | 1996-08-21 | 1998-07-14 | Brooks; Benjamin Rix | Method for treating amyotrophic lateral sclerosis |
| JP3889844B2 (ja) * | 1997-02-10 | 2007-03-07 | 龍兒 梶 | 筋萎縮性側索硬化症治療剤 |
| FR2782008B1 (fr) * | 1998-08-07 | 2003-04-25 | Sod Conseils Rech Applic | Utilisation d'extraits de ginkgo biloba pour preparer un medicament destine a traiter la sclerose laterale amyotrophique |
-
1998
- 1998-11-13 FR FR9814250A patent/FR2785808B1/fr not_active Expired - Fee Related
-
1999
- 1999-11-09 DK DK99972101T patent/DK1128829T3/da active
- 1999-11-09 EA EA200100530A patent/EA003671B1/ru not_active IP Right Cessation
- 1999-11-09 PT PT99972101T patent/PT1128829E/pt unknown
- 1999-11-09 CN CNB998131903A patent/CN1177587C/zh not_active Expired - Fee Related
- 1999-11-09 AU AU11655/00A patent/AU776242B2/en not_active Ceased
- 1999-11-09 HU HU0105301A patent/HU226067B1/hu not_active IP Right Cessation
- 1999-11-09 CZ CZ20011561A patent/CZ298808B6/cs not_active IP Right Cessation
- 1999-11-09 JP JP2000582039A patent/JP4693241B2/ja not_active Expired - Fee Related
- 1999-11-09 AT AT99972101T patent/ATE295168T1/de active
- 1999-11-09 TR TR2001/01346T patent/TR200101346T2/xx unknown
- 1999-11-09 WO PCT/FR1999/002753 patent/WO2000028992A1/fr active IP Right Grant
- 1999-11-09 BR BR9915292-4A patent/BR9915292A/pt not_active Application Discontinuation
- 1999-11-09 IL IL14270899A patent/IL142708A0/xx not_active IP Right Cessation
- 1999-11-09 ES ES99972101T patent/ES2239858T3/es not_active Expired - Lifetime
- 1999-11-09 KR KR1020017005912A patent/KR100641472B1/ko not_active Expired - Fee Related
- 1999-11-09 EP EP99972101A patent/EP1128829B1/fr not_active Expired - Lifetime
- 1999-11-09 CA CA2350671A patent/CA2350671C/fr not_active Expired - Fee Related
- 1999-11-09 DE DE69925301T patent/DE69925301T2/de not_active Expired - Lifetime
-
2001
- 2001-05-10 ZA ZA200103810A patent/ZA200103810B/en unknown
- 2001-05-10 NO NO20012308A patent/NO328349B1/no not_active IP Right Cessation
- 2001-05-11 US US09/854,318 patent/US6642262B2/en not_active Expired - Lifetime
-
2002
- 2002-04-22 HK HK02102998.6A patent/HK1041220B/zh not_active IP Right Cessation
-
2003
- 2003-02-18 US US10/369,151 patent/US20030125363A1/en not_active Abandoned
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