DK108495C - Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. - Google Patents
Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof.Info
- Publication number
- DK108495C DK108495C DK626764A DK626764A DK108495C DK 108495 C DK108495 C DK 108495C DK 626764 A DK626764 A DK 626764A DK 626764 A DK626764 A DK 626764A DK 108495 C DK108495 C DK 108495C
- Authority
- DK
- Denmark
- Prior art keywords
- benzomorphans
- substituted
- preparation
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK108495C true DK108495C (en) | 1967-12-27 |
Family
ID=23297612
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK626764A DK108495C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
| DK429865A DK108497C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
| DK626864A DK106552C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans. |
| DK429765A DK108496C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK429865A DK108497C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
| DK626864A DK106552C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans. |
| DK429765A DK108496C (en) | 1963-12-20 | 1964-12-19 | Process for the preparation of substituted 6,7-benzomorphans or acid addition salts thereof. |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT249277B (en) |
| BE (2) | BE657405A (en) |
| CH (7) | CH448118A (en) |
| DE (2) | DE1445853A1 (en) |
| DK (4) | DK108495C (en) |
| ES (4) | ES307302A1 (en) |
| FR (2) | FR4346M (en) |
| GB (2) | GB1077711A (en) |
| IL (2) | IL22643A (en) |
| NL (3) | NL6414821A (en) |
| NO (2) | NO119274B (en) |
| SE (2) | SE322779B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP2987788A1 (en) | 2002-05-17 | 2016-02-24 | Taiwanj Pharmaceuticals Co., Ltd. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8835426B2 (en) | 2007-02-26 | 2014-09-16 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| ATE554078T1 (en) | 2007-07-26 | 2012-05-15 | Vitae Pharmaceuticals Inc | SYNTHESIS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 INHIBITORS |
| AR069207A1 (en) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
| WO2009063061A2 (en) | 2007-11-16 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| CA2712500A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CA2714532A1 (en) | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| EP2245014B1 (en) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| EP2254872A2 (en) | 2008-02-15 | 2010-12-01 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| CL2009001059A1 (en) | 2008-05-01 | 2010-11-12 | Boehringer Ingelheim Int | Compounds derived from substituted 1,3-oxazin-2-one-3.6, inhibitors of the activity of 11-beta-hydroxysteroid dehydrogenase i; pharmaceutical composition that includes them; Useful in the treatment of diseases such as diabetes mellitus, among others. |
| US8592410B2 (en) | 2008-05-01 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11BETA-hydroxysteroid dehydrogenase 1 |
| EP2291371B1 (en) | 2008-05-01 | 2015-06-10 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| EP2291373B1 (en) | 2008-05-01 | 2013-09-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TW200950780A (en) | 2008-05-13 | 2009-12-16 | Boehringer Ingelheim Int | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| PE20110566A1 (en) | 2008-07-25 | 2011-09-02 | Boehringer Ingelheim Int | CYCLIC INHIBITORS OF 11BETA-HYDROXIESTEROID DEHYDROGENASE 1 |
| TW201016691A (en) | 2008-07-25 | 2010-05-01 | Boehringer Ingelheim Int | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8829027B2 (en) | 2008-10-23 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| US8637505B2 (en) | 2009-02-04 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8703765B2 (en) | 2009-06-02 | 2014-04-22 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5656986B2 (en) | 2009-06-11 | 2015-01-21 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 based on 1,3-oxazinan-2-one structure |
| EP2448928B1 (en) | 2009-07-01 | 2014-08-13 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| UY33001A (en) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | ARYL AND HETEROARILCARBONYL HIVAHYDROINDENOPIRIDINE AND OCTAHYDROBENZOQUINOLINE DERIVATIVES |
| EP2582698B1 (en) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| EP2585444B1 (en) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
| EA201300522A1 (en) | 2010-11-02 | 2013-11-29 | Бёрингер Ингельхайм Интернациональ Гмбх | PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF METABOLIC DISORDERS |
| TWI537258B (en) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| JP2014524438A (en) | 2011-08-17 | 2014-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1538364A patent/CH448118A/en unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/en unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/en unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/en unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/en unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/en unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/en unknown
- 1964-12-18 AT AT392965A patent/AT249277B/en active
- 1964-12-18 AT AT1074264A patent/AT261126B/en active
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 IL IL2264364A patent/IL22643A/en unknown
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/en active Pending
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 AT AT1074364A patent/AT253687B/en active
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/en active Pending
- 1964-12-18 AT AT392865A patent/AT249276B/en active
- 1964-12-18 IL IL2264264A patent/IL22642A/en unknown
- 1964-12-19 ES ES0307302A patent/ES307302A1/en not_active Expired
- 1964-12-19 DK DK626764A patent/DK108495C/en active
- 1964-12-19 DK DK429865A patent/DK108497C/en active
- 1964-12-19 DK DK626864A patent/DK106552C/en active
- 1964-12-19 ES ES0307300A patent/ES307300A1/en not_active Expired
- 1964-12-19 ES ES0307299A patent/ES307299A1/en not_active Expired
- 1964-12-19 DK DK429765A patent/DK108496C/en active
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 ES ES0307301A patent/ES307301A1/en not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SE322779B (en) | 1970-04-20 |
| ES307302A1 (en) | 1965-05-16 |
| NO119273B (en) | 1970-04-27 |
| CH448118A (en) | 1967-12-15 |
| DK108496C (en) | 1967-12-27 |
| AT253687B (en) | 1967-04-25 |
| CH449643A (en) | 1968-01-15 |
| NO119274B (en) | 1970-04-27 |
| DE1445853A1 (en) | 1968-12-05 |
| GB1077711A (en) | 1967-08-02 |
| DK108497C (en) | 1967-12-27 |
| IL22643A (en) | 1968-07-25 |
| FR4346M (en) | 1966-08-16 |
| AT249276B (en) | 1966-09-12 |
| CH449641A (en) | 1968-01-15 |
| CH449642A (en) | 1968-01-15 |
| ES307300A1 (en) | 1965-05-01 |
| BE657405A (en) | 1965-06-21 |
| CH449640A (en) | 1968-01-15 |
| NL6414821A (en) | 1965-06-21 |
| AT261126B (en) | 1968-04-10 |
| SE305657B (en) | 1968-11-04 |
| CH449639A (en) | 1968-01-15 |
| CH446371A (en) | 1967-11-15 |
| DK106552C (en) | 1967-02-20 |
| AT249277B (en) | 1966-09-12 |
| NL127995C (en) | |
| ES307299A1 (en) | 1965-05-16 |
| BE657406A (en) | 1965-06-21 |
| NL6414820A (en) | 1965-06-21 |
| GB1092394A (en) | 1967-11-22 |
| FR4345M (en) | 1966-08-16 |
| IL22642A (en) | 1968-07-25 |
| DE1445854A1 (en) | 1968-12-05 |
| ES307301A1 (en) | 1965-05-16 |
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