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DK0992794T3 - Enzym-antistofkompleks og en fremgangsmåde til fremstilling heraf - Google Patents

Enzym-antistofkompleks og en fremgangsmåde til fremstilling heraf

Info

Publication number
DK0992794T3
DK0992794T3 DK99105375T DK99105375T DK0992794T3 DK 0992794 T3 DK0992794 T3 DK 0992794T3 DK 99105375 T DK99105375 T DK 99105375T DK 99105375 T DK99105375 T DK 99105375T DK 0992794 T3 DK0992794 T3 DK 0992794T3
Authority
DK
Denmark
Prior art keywords
enzyme
preparation
antibody complex
antibody
complex
Prior art date
Application number
DK99105375T
Other languages
English (en)
Inventor
Hirokazu Ohabayashi
Yuriko Kitano
Takashi Kitoh
Original Assignee
Nichirei Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nichirei Kk filed Critical Nichirei Kk
Application granted granted Critical
Publication of DK0992794T3 publication Critical patent/DK0992794T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK99105375T 1998-09-16 1999-03-16 Enzym-antistofkompleks og en fremgangsmåde til fremstilling heraf DK0992794T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27931998A JP3524401B2 (ja) 1998-09-16 1998-09-16 酵素抗体複合体およびその製造方法

Publications (1)

Publication Number Publication Date
DK0992794T3 true DK0992794T3 (da) 2002-12-30

Family

ID=17609526

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99105375T DK0992794T3 (da) 1998-09-16 1999-03-16 Enzym-antistofkompleks og en fremgangsmåde til fremstilling heraf

Country Status (6)

Country Link
US (1) US6252053B1 (da)
EP (1) EP0992794B1 (da)
JP (1) JP3524401B2 (da)
DE (1) DE69903899T2 (da)
DK (1) DK0992794T3 (da)
ES (1) ES2183451T3 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
JP3781934B2 (ja) * 1999-12-22 2006-06-07 株式会社ニチレイバイオサイエンス 酵素−タンパク質複合体
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
US20040248223A1 (en) * 2003-06-05 2004-12-09 Idexx Laboratories, Inc. Reduction of interfering peroxidase activity in peroxidase based detection methods
US20050186642A1 (en) 2004-02-24 2005-08-25 Biocare Medical, Inc. Immunoassay reagents and methods of use thereof
CA2574683C (en) * 2004-07-30 2013-05-28 Advanced Life Science Institute, Inc. Probe complex
CA2592274C (en) * 2004-12-28 2014-09-09 Advanced Life Science Institute, Inc. Blocked enzyme-probe complex
JP2008541015A (ja) * 2005-04-28 2008-11-20 ベンタナ・メデイカル・システムズ・インコーポレーテツド ナノ粒子コンジュゲート
ES2609919T3 (es) * 2005-04-28 2017-04-25 Ventana Medical Systems, Inc. Enzimas conjugados con anticuerpos mediante un conector de PEG heterobifuncional
US8093012B2 (en) * 2005-10-13 2012-01-10 Aureon Laboratories, Inc. Multiplex in situ immunohistochemical analysis
CA2631005C (en) * 2005-11-23 2017-02-28 Ventana Medical Systems, Inc. Molecular conjugate
DE602007008581D1 (de) * 2006-08-25 2010-09-30 Cliniques Universitaires Saint Verfahren zur bestimmung des antigengehalts in einer probe unter verwendung eines immunhistochemischen doppelnachweises
JP5334691B2 (ja) * 2009-06-04 2013-11-06 キッコーマン株式会社 ペルオキシダーゼ化学発光測定試薬
JP5311662B2 (ja) * 2009-08-24 2013-10-09 キッコーマン株式会社 ペルオキシダーゼ化学発光反応の発光増強方法及びペルオキシダーゼ化学発光反応用発光増強剤
JP5675782B2 (ja) 2010-04-14 2015-02-25 栄研化学株式会社 標識化プローブ−水溶性担体複合体
WO2012154983A2 (en) 2011-05-10 2012-11-15 Biocare Medical, Llc Systems and methods for anti-pax8 antibodies
US10316103B1 (en) 2012-03-30 2019-06-11 Biocare Medical, Llc Systems and methods for anti-Uroplakin III antibodies
WO2014052672A1 (en) 2012-09-27 2014-04-03 Biocare Medical, Llc Anti-uroplakin ii antibodies systems and methods
US10429390B2 (en) 2012-12-18 2019-10-01 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
EP2962113B1 (en) 2013-02-28 2019-04-03 Biocare Medical, LLC Anti-p40 antibodies systems and methods
EP3015474A4 (en) 2013-06-28 2017-01-11 Kyushu University, National University Corporation PROTEIN-POLYMER COMPLEX, TGase SUBSTRATE-CONTAINING POLYMER, TGase SUBSTRATE-CONTAINING MONOMER, METHOD FOR PRODUCING PROTEIN-POLYMER COMPLEX, AND METHOD FOR IMPROVING PROTEIN FUNCTION ON INTERFACE OR IN VICINITIY OF INTERFACE OF SOLID-LIQUID
JP6506267B2 (ja) 2013-10-03 2019-04-24 バイオケア メディカル， エルエルシー 抗ｓｏｘ１０抗体のシステムおよび方法
JP6019254B2 (ja) 2014-04-23 2016-11-02 株式会社ニチレイバイオサイエンス 標的マーカー検出用組合せ物
US11293921B2 (en) 2018-10-03 2022-04-05 Arkray, Inc. Direct electron transfer-type oxidoreductase-modified molecular recognition element
CN118362716A (zh) 2018-12-28 2024-07-19 雅培制药有限公司 微粒上的单分子的直接检测
CN111830250A (zh) * 2020-08-04 2020-10-27 珠海市丽拓生物科技有限公司 一种信号放大的酶标二抗的制备方法
CN113391059B (zh) * 2021-06-10 2022-06-03 上海百英生物科技有限公司 一种micropolymer-HRP-纳米抗体复合物及其制备方法
CN116448996B (zh) * 2023-03-22 2023-11-21 卡秋(江苏)生物科技有限公司 一种串珠结构的多聚酶-抗体复合物的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225028A (ja) 1982-06-25 1983-12-27 Otsuka Pharmaceut Co Ltd ヒトα型インターフェロン抗体
JPS61205863A (ja) 1985-03-09 1986-09-12 Meidensha Electric Mfg Co Ltd 酵素標識抗体の調製法およびその抗体
US5057313A (en) 1986-02-25 1991-10-15 The Center For Molecular Medicine And Immunology Diagnostic and therapeutic antibody conjugates
US5084560A (en) * 1986-06-30 1992-01-28 Oncogen Immunoconjugates and methods for their use in tumor therapy
JPH0266459A (ja) 1988-08-31 1990-03-06 Sekisui Chem Co Ltd 酵素標識抗体および酵素免疫測定法
US5053520A (en) * 1988-09-22 1991-10-01 Abbott Laboratories Heterobifunctional maleimido containing coupling agents
JPH02201162A (ja) 1989-01-30 1990-08-09 Teijin Ltd 酵素抗体複合体、複合体―抗体の組合せ、キット及び診断方法
JPH0389164A (ja) 1989-08-31 1991-04-15 Meidensha Corp 酵素免疫測定用試薬及びその調製方法
JPH0389165A (ja) 1989-08-31 1991-04-15 Meidensha Corp 酵素免疫測定用試薬及びその調製方法
JPH10507997A (ja) 1993-06-11 1998-08-04 クールター コーポレイション Ｔ細胞の活性化および増殖を誘導するための抗ｃｄ３抗体−アミノデキストラン結合体

Also Published As

Publication number Publication date
DE69903899D1 (de) 2002-12-19
US6252053B1 (en) 2001-06-26
DE69903899T2 (de) 2003-07-17
JP3524401B2 (ja) 2004-05-10
JP2000088850A (ja) 2000-03-31
ES2183451T3 (es) 2003-03-16
EP0992794A3 (en) 2000-04-19
EP0992794A2 (en) 2000-04-12
EP0992794B1 (en) 2002-11-13

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