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DK0986577T3 - Opsonisk og beskyttende monoklonale og kimære antistoffer specifikke for lipoteichoicsyre af grampositive bakterier - Google Patents

Opsonisk og beskyttende monoklonale og kimære antistoffer specifikke for lipoteichoicsyre af grampositive bakterier

Info

Publication number
DK0986577T3
DK0986577T3 DK98931278.0T DK98931278T DK0986577T3 DK 0986577 T3 DK0986577 T3 DK 0986577T3 DK 98931278 T DK98931278 T DK 98931278T DK 0986577 T3 DK0986577 T3 DK 0986577T3
Authority
DK
Denmark
Prior art keywords
gram
opsonic
positive bacteria
lipoteichoic acid
antibodies specific
Prior art date
Application number
DK98931278.0T
Other languages
English (en)
Inventor
Richard F Schuman
Jeffrey L Stinson
Gerald W Fischer
Hing Wong
Original Assignee
Jackson H M Found Military Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jackson H M Found Military Med filed Critical Jackson H M Found Military Med
Application granted granted Critical
Publication of DK0986577T3 publication Critical patent/DK0986577T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK98931278.0T 1997-06-16 1998-06-16 Opsonisk og beskyttende monoklonale og kimære antistoffer specifikke for lipoteichoicsyre af grampositive bakterier DK0986577T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4987197P 1997-06-16 1997-06-16
PCT/US1998/012402 WO1998057994A2 (en) 1997-06-16 1998-06-16 Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria

Publications (1)

Publication Number Publication Date
DK0986577T3 true DK0986577T3 (da) 2011-05-23

Family

ID=21962176

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98931278.0T DK0986577T3 (da) 1997-06-16 1998-06-16 Opsonisk og beskyttende monoklonale og kimære antistoffer specifikke for lipoteichoicsyre af grampositive bakterier

Country Status (10)

Country Link
US (5) US6610293B1 (da)
EP (2) EP0986577B1 (da)
JP (2) JP4691225B2 (da)
AT (1) ATE497977T1 (da)
AU (1) AU8144098A (da)
CA (1) CA2293732A1 (da)
DE (1) DE69842129D1 (da)
DK (1) DK0986577T3 (da)
ES (1) ES2363689T3 (da)
WO (1) WO1998057994A2 (da)

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WO1998057994A2 (en) 1998-12-23
JP2002503966A (ja) 2002-02-05
ATE497977T1 (de) 2011-02-15
US7884198B2 (en) 2011-02-08
CA2293732A1 (en) 1998-12-23
US20020082395A1 (en) 2002-06-27
US7511122B2 (en) 2009-03-31
AU8144098A (en) 1999-01-04
EP0986577A2 (en) 2000-03-22
US20060002939A1 (en) 2006-01-05
ES2363689T3 (es) 2011-08-11
US6610293B1 (en) 2003-08-26
DE69842129D1 (de) 2011-03-24
JP4691225B2 (ja) 2011-06-01
US20100221822A1 (en) 2010-09-02
EP0986577B1 (en) 2011-02-09
US6939543B2 (en) 2005-09-06
EP2357198A1 (en) 2011-08-17
WO1998057994A3 (en) 1999-03-25
US8372958B2 (en) 2013-02-12
JP2011026327A (ja) 2011-02-10

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