DK0929299T3 - Substituerede 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyclohepta-(b)benzofuraner - Google Patents

Substituerede 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyclohepta-(b)benzofuraner

Info

Publication number: DK0929299T3
Authority: DK; Denmark
Prior art keywords: aminocyclohepta; substituted; dibenzofuranamines; benzofurans; tetrahydro
Prior art date: 1996-08-28

Application number

DK97938585T

Other languages

English (en)

Inventor

Michael E Flaugh

Junior Anton D Kiefer

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-28

Filing date

1997-08-25

Publication date

2004-02-16

1997-08-25 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2004-02-16 Application granted granted Critical

2004-02-16 Publication of DK0929299T3 publication Critical patent/DK0929299T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Polyethers (AREA)

DK97938585T 1996-08-28 1997-08-25 Substituerede 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyclohepta-(b)benzofuraner DK0929299T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2474596P	1996-08-28	1996-08-28
PCT/US1997/014938 WO1998008502A1 (en)	1996-08-28	1997-08-25	SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA[b]BENZOFURANS

Publications (1)

Publication Number	Publication Date
DK0929299T3 true DK0929299T3 (da)	2004-02-16

Family

ID=21822177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97938585T DK0929299T3 (da)	1996-08-28	1997-08-25	Substituerede 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyclohepta-(b)benzofuraner

Country Status (23)

Country	Link
EP (1)	EP0929299B1 (da)
JP (1)	JP2000516957A (da)
KR (1)	KR20000035942A (da)
CN (1)	CN1228695A (da)
AT (1)	ATE251457T1 (da)
AU (1)	AU741324B2 (da)
BR (1)	BR9711273A (da)
CA (1)	CA2264267A1 (da)
CZ (1)	CZ64499A3 (da)
DE (1)	DE69725459T2 (da)
DK (1)	DK0929299T3 (da)
EA (1)	EA001912B1 (da)
ES (1)	ES2208948T3 (da)
HU (1)	HUP9902901A3 (da)
IL (1)	IL128500A (da)
NO (1)	NO990849D0 (da)
NZ (1)	NZ334031A (da)
PL (1)	PL331882A1 (da)
PT (1)	PT929299E (da)
TR (1)	TR199900430T2 (da)
UA (1)	UA48245C2 (da)
WO (1)	WO1998008502A1 (da)
YU (1)	YU10499A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA52778C2 (uk)	1997-10-10	2003-01-15	Янссен Фармацевтика Н.В.	Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
TWI263497B (en)	2002-03-29	2006-10-11	Lilly Co Eli	Pyridinoylpiperidines as 5-HT1F agonists
BRPI0409211A (pt)	2003-04-18	2006-03-28	Lilly Co Eli	composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto
UA82711C2 (en)	2003-09-12	2008-05-12	Эли Лилли Энд Компани	Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
DE602004008338T2 (de)	2003-12-17	2008-05-29	Eli Lilly And Co., Indianapolis	Substituierte (4-aminocyclohexen-1-yl) phenyl and (4-aminocyclohexen-1-yl) pyridinyl verbindungen als 5-ht1f agonisten
CN1318411C (zh) *	2005-03-21	2007-05-30	中国海洋大学	氢化轮枝霉酮类化合物及其制备方法和用途
PL2413933T5 (pl)	2009-04-02	2021-10-18	Colucid Pharmaceuticals, Inc.	2,4,6-trifluoro-N-[6-(1-metylopiperydyno-4-karbonylo)pirydyn-2-ylo]benzamid do leczenia migreny drogą doustną lub dożylną
US8697876B2 (en)	2010-04-02	2014-04-15	Colucid Pharmaceuticals, Inc.	Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists
CN102887880B (zh) *	2012-08-20	2014-10-29	东南大学	二苯并呋喃衍生物及其制备方法与用途
TWI826514B (zh)	2018-09-04	2023-12-21	美商美國禮來大藥廠	用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
TWI776175B (zh)	2019-07-09	2022-09-01	美商美國禮來大藥廠	大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4668690A (en) *	1985-12-30	1987-05-26	Hoechst Roussel Pharmaceuticals Inc.	1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans useful as analgesics, anticonvulsants or antidepressants
US5698571A (en) *	1994-10-05	1997-12-16	Eli Lilly And Company	5-HT1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine
US5521196A (en) *	1994-10-05	1996-05-28	Eli Lilly And Company	5-HT1F agonists for the treatment of migraine

1997
- 1997-08-25 JP JP10511794A patent/JP2000516957A/ja not_active Ceased
- 1997-08-25 NZ NZ334031A patent/NZ334031A/xx unknown
- 1997-08-25 TR TR1999/00430T patent/TR199900430T2/xx unknown
- 1997-08-25 DK DK97938585T patent/DK0929299T3/da active
- 1997-08-25 IL IL12850097A patent/IL128500A/xx not_active IP Right Cessation
- 1997-08-25 CA CA002264267A patent/CA2264267A1/en not_active Abandoned
- 1997-08-25 CN CN97197483A patent/CN1228695A/zh active Pending
- 1997-08-25 HU HU9902901A patent/HUP9902901A3/hu unknown
- 1997-08-25 EA EA199900241A patent/EA001912B1/ru not_active IP Right Cessation
- 1997-08-25 PT PT97938585T patent/PT929299E/pt unknown
- 1997-08-25 KR KR1019997001683A patent/KR20000035942A/ko not_active Ceased
- 1997-08-25 UA UA99021147A patent/UA48245C2/uk unknown
- 1997-08-25 ES ES97938585T patent/ES2208948T3/es not_active Expired - Lifetime
- 1997-08-25 WO PCT/US1997/014938 patent/WO1998008502A1/en not_active Ceased
- 1997-08-25 BR BR9711273A patent/BR9711273A/pt not_active IP Right Cessation
- 1997-08-25 AU AU40880/97A patent/AU741324B2/en not_active Ceased
- 1997-08-25 PL PL97331882A patent/PL331882A1/xx unknown
- 1997-08-25 DE DE69725459T patent/DE69725459T2/de not_active Expired - Fee Related
- 1997-08-25 EP EP97938585A patent/EP0929299B1/en not_active Expired - Lifetime
- 1997-08-25 YU YU10499A patent/YU10499A/sh unknown
- 1997-08-25 AT AT97938585T patent/ATE251457T1/de not_active IP Right Cessation
- 1997-08-25 CZ CZ99644A patent/CZ64499A3/cs unknown
1999
- 1999-02-23 NO NO990849A patent/NO990849D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1998008502A1 (en)	1998-03-05
YU10499A (sh)	2001-03-07
HUP9902901A2 (hu)	2000-05-28
ATE251457T1 (de)	2003-10-15
AU741324B2 (en)	2001-11-29
NZ334031A (en)	2000-07-28
HUP9902901A3 (en)	2002-01-28
CN1228695A (zh)	1999-09-15
NO990849L (no)	1999-02-23
BR9711273A (pt)	1999-08-17
DE69725459D1 (de)	2003-11-13
EP0929299A1 (en)	1999-07-21
JP2000516957A (ja)	2000-12-19
CA2264267A1 (en)	1998-03-05
CZ64499A3 (cs)	1999-05-12
EP0929299B1 (en)	2003-10-08
UA48245C2 (uk)	2002-08-15
KR20000035942A (ko)	2000-06-26
ES2208948T3 (es)	2004-06-16
EA001912B1 (ru)	2001-10-22
EA199900241A1 (ru)	1999-08-26
IL128500A (en)	2003-06-24
DE69725459T2 (de)	2004-08-12
AU4088097A (en)	1998-03-19
PL331882A1 (en)	1999-08-16
TR199900430T2 (xx)	1999-06-21
IL128500A0 (en)	2000-01-31
PT929299E (pt)	2004-02-27
EP0929299A4 (en)	2000-12-20
NO990849D0 (no)	1999-02-23

Publication	Publication Date	Title
ID18249A (id)	1998-03-19	Turunan 6,5-hetero-bisiklik tersubstitusi
DE59712738D1 (de)	2006-11-09	2- und 2,5-substituierte Phenylketoenole
DK0920429T3 (da)	2003-05-12	Substituerede pyrido- eller pyrimidoholdige, 6,6- eller 6,7-bicykliske derivater
YU15299A (sh)	2002-06-19	Farmaceutski sastavi
ID18189A (id)	1998-03-12	Dervat-derivat 6,6-hetero-bisiklik yang disubstitusi
NL1007028A1 (nl)	1998-03-16	Stabilisatorcombinatie.
TR199600358A2 (tr)	1996-11-21	-Adrenerjik agonistleri.
AR016981A2 (es)	2001-08-01	Polipeptidos sinteticos
TR27961A (tr)	1995-11-06	Sübstitüe edilmis 1,2,3,4 -tetrahidro-5-nitro-pirimidinler.
DK0901488T3 (da)	2003-03-03	2,4-diaminopyrimidinderivater
DK0929299T3 (da)	2004-02-16	Substituerede 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyclohepta-(b)benzofuraner
DE69202068D1 (de)	1995-05-24	Verschleissprüfverfahren.
NO983802L (no)	1998-08-19	Benzothiofener, formuleringer inneholdende samme og fremgangsmåter
DK1012186T3 (da)	2002-11-04	Keratinocyt-vækstfaktorer og anvendelser deraf
DE69906149D1 (de)	2003-04-24	4,5-azolo-oxindole
PE20399A1 (es)	1999-03-05	Muteina ob
DE69709173D1 (de)	2002-01-24	Belastungswalzenanordnüng.
TR199700219A3 (tr)	1997-10-21	1,25-Dihidroksi-16, 22, 23-Trisdihidro-kolkalsiferol türevleri.
DE59709923D1 (de)	2003-05-28	2- und 2,5-substituierte phenylketoenole
ES1035261Y (es)	1997-09-01	Jamonero.
DE69915055D1 (de)	2004-04-01	Antitumorale 1,5-diazaanthraquinone
BR9708948A (pt)	1999-08-03	1,3 - Benzodioxois substituídos
ES1033200Y (es)	1997-01-01	Linterna - caramelo.
BR9711721A (pt)	1999-08-24	Paraherquamidas e marcfortinas de 24,25-epoxi e 25-metileno
ES1033500Y (es)	1997-02-01	Caja-expositor.