DK0899267T3 - Disubstituerede trans-3,4,4a,5,6,10b-hexahydro-2H-napht[1,2-b]-1,4-oxiner, fremgangsmåde til fremstilling deraf og farmaceutiske sammensætninger indeholdende disse - Google Patents
Disubstituerede trans-3,4,4a,5,6,10b-hexahydro-2H-napht[1,2-b]-1,4-oxiner, fremgangsmåde til fremstilling deraf og farmaceutiske sammensætninger indeholdende disseInfo
- Publication number
- DK0899267T3 DK0899267T3 DK98402155T DK98402155T DK0899267T3 DK 0899267 T3 DK0899267 T3 DK 0899267T3 DK 98402155 T DK98402155 T DK 98402155T DK 98402155 T DK98402155 T DK 98402155T DK 0899267 T3 DK0899267 T3 DK 0899267T3
- Authority
- DK
- Denmark
- Prior art keywords
- hexahydro
- oxines
- napht
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9710852A FR2767825A1 (fr) | 1997-09-01 | 1997-09-01 | Nouvelles trans-3,4,4a,5,6,10b-hexahydro-2h-napht°1,2-b!-1, 4-oxazines disubstituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0899267T3 true DK0899267T3 (da) | 2003-03-10 |
Family
ID=9510643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98402155T DK0899267T3 (da) | 1997-09-01 | 1998-09-01 | Disubstituerede trans-3,4,4a,5,6,10b-hexahydro-2H-napht[1,2-b]-1,4-oxiner, fremgangsmåde til fremstilling deraf og farmaceutiske sammensætninger indeholdende disse |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6025356A (da) |
| EP (1) | EP0899267B1 (da) |
| JP (1) | JP4417451B2 (da) |
| CN (1) | CN1088064C (da) |
| AT (1) | ATE229513T1 (da) |
| AU (1) | AU740928C (da) |
| BR (1) | BR9803933A (da) |
| CA (1) | CA2246482C (da) |
| DE (1) | DE69810034T2 (da) |
| DK (1) | DK0899267T3 (da) |
| ES (1) | ES2189108T3 (da) |
| FR (1) | FR2767825A1 (da) |
| HK (1) | HK1020340A1 (da) |
| HU (1) | HU226059B1 (da) |
| NO (1) | NO311218B1 (da) |
| NZ (1) | NZ331637A (da) |
| PL (1) | PL194533B1 (da) |
| PT (1) | PT899267E (da) |
| ZA (1) | ZA987963B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0130219D0 (en) * | 2001-12-18 | 2002-02-06 | Pfizer Ltd | Compounds for the treatment of sexual dysfunction |
| MXPA05002331A (es) * | 2002-08-30 | 2005-08-18 | Biostratum Inc | Inhibidores de productos terminales de glicacion avanzada post-amadori. |
| JP2006523674A (ja) * | 2003-04-18 | 2006-10-19 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 慢性閉塞性肺疾患（ｃｏｐｄ）のための組合せ治療法 |
| FR2906249B1 (fr) * | 2006-09-26 | 2008-12-19 | Servier Lab | Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP2098511A1 (en) | 2008-03-07 | 2009-09-09 | Solvias AG | Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring |
| WO2009156458A1 (en) * | 2008-06-27 | 2009-12-30 | H. Lundbeck A/S | Novel phenolic and catecholic amines and prodrugs thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1204745A (en) * | 1981-11-20 | 1986-05-20 | Merck Co. | Hexahydronaphth (1,2-b) -1,4 -oxazines |
| US4420480A (en) * | 1981-11-20 | 1983-12-13 | Merck & Co., Inc. | Hexahydronaphth[1,2-b]-1,4-oxazines |
| US4540691A (en) * | 1984-04-13 | 1985-09-10 | Nelson Research & Development Co. | Dopamine agonists and use thereof |
| US5486611A (en) * | 1989-07-13 | 1996-01-23 | The Upjohn Company | Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives |
| AU651608B2 (en) * | 1990-06-15 | 1994-07-28 | Discovery Therapeutics, Inc. | Substituted naphthoxazines useful as dopaminergics |
-
1997
- 1997-09-01 FR FR9710852A patent/FR2767825A1/fr active Pending
-
1998
- 1998-08-31 PL PL328285A patent/PL194533B1/pl not_active IP Right Cessation
- 1998-08-31 CN CN98119987A patent/CN1088064C/zh not_active Expired - Fee Related
- 1998-08-31 NZ NZ331637A patent/NZ331637A/xx not_active IP Right Cessation
- 1998-08-31 NO NO19984007A patent/NO311218B1/no not_active IP Right Cessation
- 1998-08-31 US US09/144,025 patent/US6025356A/en not_active Expired - Lifetime
- 1998-08-31 BR BR9803933-4A patent/BR9803933A/pt not_active Application Discontinuation
- 1998-08-31 CA CA002246482A patent/CA2246482C/fr not_active Expired - Fee Related
- 1998-08-31 HU HU9801951A patent/HU226059B1/hu not_active IP Right Cessation
- 1998-09-01 DE DE69810034T patent/DE69810034T2/de not_active Expired - Lifetime
- 1998-09-01 ZA ZA987963A patent/ZA987963B/xx unknown
- 1998-09-01 AT AT98402155T patent/ATE229513T1/de active
- 1998-09-01 ES ES98402155T patent/ES2189108T3/es not_active Expired - Lifetime
- 1998-09-01 PT PT98402155T patent/PT899267E/pt unknown
- 1998-09-01 AU AU83024/98A patent/AU740928C/en not_active Ceased
- 1998-09-01 DK DK98402155T patent/DK0899267T3/da active
- 1998-09-01 JP JP24691098A patent/JP4417451B2/ja not_active Expired - Fee Related
- 1998-09-01 EP EP98402155A patent/EP0899267B1/fr not_active Expired - Lifetime
-
1999
- 1999-11-25 HK HK99105446A patent/HK1020340A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6025356A (en) | 2000-02-15 |
| FR2767825A1 (fr) | 1999-02-26 |
| EP0899267B1 (fr) | 2002-12-11 |
| DE69810034T2 (de) | 2003-08-14 |
| PT899267E (pt) | 2003-04-30 |
| AU740928B2 (en) | 2001-11-15 |
| NO311218B1 (no) | 2001-10-29 |
| JP4417451B2 (ja) | 2010-02-17 |
| NZ331637A (en) | 1999-07-29 |
| CN1088064C (zh) | 2002-07-24 |
| HU226059B1 (en) | 2008-04-28 |
| HK1020340A1 (en) | 2000-04-14 |
| ATE229513T1 (de) | 2002-12-15 |
| NO984007D0 (no) | 1998-08-31 |
| NO984007L (no) | 1999-03-02 |
| EP0899267A1 (fr) | 1999-03-03 |
| ZA987963B (en) | 1999-03-04 |
| ES2189108T3 (es) | 2003-07-01 |
| JPH11130759A (ja) | 1999-05-18 |
| CN1222516A (zh) | 1999-07-14 |
| PL328285A1 (en) | 1999-03-15 |
| HUP9801951A3 (en) | 2000-04-28 |
| AU8302498A (en) | 1999-03-11 |
| PL194533B1 (pl) | 2007-06-29 |
| CA2246482C (fr) | 2002-11-26 |
| AU740928C (en) | 2002-05-16 |
| HUP9801951A2 (hu) | 2000-02-28 |
| HU9801951D0 (en) | 1998-11-30 |
| CA2246482A1 (fr) | 1999-03-01 |
| BR9803933A (pt) | 2001-04-24 |
| DE69810034D1 (de) | 2003-01-23 |
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