DK0880964T3 - Aldosereduktaseinhibition til forebyggelse eller reversering af diabetisk cardiomyopati - Google Patents

Aldosereduktaseinhibition til forebyggelse eller reversering af diabetisk cardiomyopati

Info

Publication number: DK0880964T3
Authority: DK; Denmark
Prior art keywords: reversal; prevention; aldose reductase; diabetic cardiomyopathy; reductase inhibition
Prior art date: 1997-05-05

Application number

DK98303447T

Other languages

English (en)

Inventor

Brian Frank Johnson

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-05

Filing date

1998-05-01

Publication date

2004-12-27

1998-05-01 Application filed by Pfizer filed Critical Pfizer

2004-12-27 Application granted granted Critical

2004-12-27 Publication of DK0880964T3 publication Critical patent/DK0880964T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK98303447T 1997-05-05 1998-05-01 Aldosereduktaseinhibition til forebyggelse eller reversering af diabetisk cardiomyopati DK0880964T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4582297P	1997-05-05	1997-05-05

Publications (1)

Publication Number	Publication Date
DK0880964T3 true DK0880964T3 (da)	2004-12-27

Family

ID=21940071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98303447T DK0880964T3 (da)	1997-05-05	1998-05-01	Aldosereduktaseinhibition til forebyggelse eller reversering af diabetisk cardiomyopati

Country Status (17)

Country	Link
US (1)	US5990111A (da)
EP (1)	EP0880964B1 (da)
JP (1)	JP3010153B2 (da)
KR (1)	KR19980086748A (da)
AT (1)	ATE277607T1 (da)
AU (1)	AU725621B2 (da)
CA (1)	CA2236553C (da)
DE (1)	DE69826561T2 (da)
DK (1)	DK0880964T3 (da)
ES (1)	ES2227773T3 (da)
HU (1)	HUP9801022A3 (da)
IL (1)	IL124236A (da)
MY (1)	MY136261A (da)
NZ (1)	NZ330359A (da)
PT (1)	PT880964E (da)
TW (1)	TW589184B (da)
ZA (1)	ZA983720B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6413965B1 (en) *	1999-06-30	2002-07-02	Pfizer Inc.	Compositions and treatment for diabetic complications
US6426341B1 (en) *	1999-06-30	2002-07-30	Pfizer Inc.	Treatment for diabetic complications
US6555540B1 (en) *	1999-06-30	2003-04-29	Pfizer Inc	Combinations of aldose reductase inhibitors and selective cyclooxygenase-2 inhibitors
AU7063300A (en) *	1999-08-23	2001-03-19	University Of Virginia Patent Foundation	Method and apparatus for predicting the risk of hypoglycemia
US6380200B1 (en) *	1999-12-07	2002-04-30	Pfizer, Inc.	Combination of aldose reductase inhibitors and selective serotonin reuptake inhibitors for the treatment of diabetic complications
EP1106210A3 (en) *	1999-12-07	2003-12-03	Pfizer Products Inc.	Combination of aldose reductase inhibitors and antihypertensive agents for the treatment of diabetic complications
CO5271699A1 (es)	2000-01-24	2003-04-30	Pfizer Prod Inc	Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
WO2002079506A1 (en) *	2001-03-30	2002-10-10	The Chinese University Of Hong Kong	Determination of risk factors for cataract by aldose reductase genotype
US20040047919A1 (en) *	2002-06-13	2004-03-11	Board Of Regents, The University Of Texas System	Methods and compositions involving aldose reductase inhibitors
US20110092566A1 (en) *	2004-11-19	2011-04-21	Srivastava Satish K	Treatment of cancer with aldose reductase inhibitors
EP2848252A3 (en)	2007-03-23	2015-06-17	The Board of Regents of the University of Texas System	Aldose reductase inhibitors for use in treating uveitis
US20090270490A1 (en) *	2008-04-24	2009-10-29	The Board Of Regents Of The University Of Texas System	Methods involving aldose reductase inhibition
JP5976010B2 (ja)	2010-12-23	2016-08-23	ザボードオブリージェンツオブザユニバーシティーオブテキサスシステム	Ｃｏｐｄを処置する方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4748280A (en) *	1985-11-07	1988-05-31	Pfizer Inc.	Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6)
US4939140A (en) *	1985-11-07	1990-07-03	Pfizer Inc.	Heterocyclic oxophthalazinyl acetic acids
ES2032749T3 (es) *	1985-11-07	1993-03-01	Pfizer Inc.	Acidos oxoftalazinil-aceticos heterociclicos.
US4743611A (en) *	1986-07-02	1988-05-10	American Home Products Corp.	Naphthalenylsulfonylimidazolidinediones and their thioxo analogs useful as aldose reductase inhibitors
JPH0676391B2 (ja) *	1987-06-09	1994-09-28	フアイザー・インコーポレイテツド	ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
US4868301A (en) *	1987-06-09	1989-09-19	Pfizer Inc.	Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
EP0322153A3 (en) *	1987-12-21	1990-08-16	Pfizer Inc.	Heterocyclic oxophtalazinyl acetic acids
US4954629A (en) *	1989-05-11	1990-09-04	Pfizer Inc.	Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US5164391A (en) *	1989-09-20	1992-11-17	Sanwa Kagaku Kenkyusho Co., Ltd.	Hydantoin derivatives for treating complications of diabetes and circulatory diseases
US5304557A (en) *	1989-12-15	1994-04-19	Pfizer Inc.	Substituted oxoophthalazinyl acetic acids and analogs thereof
US5064830A (en) *	1990-08-02	1991-11-12	Pfizer Inc.	Lowering of blood uric acid levels
JP2789134B2 (ja) *	1992-09-28	1998-08-20	ファイザー・インク．	糖尿病の合併症を制御する置換ピリミジン類
US5391551A (en) *	1993-05-10	1995-02-21	Pfizer Inc.	Method of lowering blood lipid levels
US5834466A (en) *	1994-12-22	1998-11-10	The Regents Of The University Of California	Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia

1998
- 1998-04-27 IL IL12423698A patent/IL124236A/xx not_active IP Right Cessation
- 1998-04-30 TW TW087106684A patent/TW589184B/zh not_active IP Right Cessation
- 1998-05-01 CA CA002236553A patent/CA2236553C/en not_active Expired - Fee Related
- 1998-05-01 ES ES98303447T patent/ES2227773T3/es not_active Expired - Lifetime
- 1998-05-01 DE DE69826561T patent/DE69826561T2/de not_active Expired - Fee Related
- 1998-05-01 PT PT98303447T patent/PT880964E/pt unknown
- 1998-05-01 AT AT98303447T patent/ATE277607T1/de not_active IP Right Cessation
- 1998-05-01 US US09/071,589 patent/US5990111A/en not_active Expired - Fee Related
- 1998-05-01 DK DK98303447T patent/DK0880964T3/da active
- 1998-05-01 EP EP98303447A patent/EP0880964B1/en not_active Expired - Lifetime
- 1998-05-04 AU AU63801/98A patent/AU725621B2/en not_active Ceased
- 1998-05-04 MY MYPI98001980A patent/MY136261A/en unknown
- 1998-05-04 KR KR1019980015947A patent/KR19980086748A/ko not_active Ceased
- 1998-05-04 HU HU9801022A patent/HUP9801022A3/hu unknown
- 1998-05-04 ZA ZA9803720A patent/ZA983720B/xx unknown
- 1998-05-04 NZ NZ330359A patent/NZ330359A/en unknown
- 1998-05-06 JP JP10123230A patent/JP3010153B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE277607T1 (de)	2004-10-15
NZ330359A (en)	2000-06-23
ES2227773T3 (es)	2005-04-01
US5990111A (en)	1999-11-23
DE69826561D1 (de)	2004-11-04
AU725621B2 (en)	2000-10-19
PT880964E (pt)	2004-12-31
CA2236553A1 (en)	1998-11-05
JPH10316588A (ja)	1998-12-02
DE69826561T2 (de)	2006-03-09
HUP9801022A3 (en)	2001-10-29
EP0880964A3 (en)	2002-07-17
HUP9801022A2 (hu)	2000-03-28
KR19980086748A (ko)	1998-12-05
MY136261A (en)	2008-09-30
TW589184B (en)	2004-06-01
ZA983720B (en)	1999-11-04
EP0880964B1 (en)	2004-09-29
IL124236A (en)	2003-01-12
EP0880964A2 (en)	1998-12-02
CA2236553C (en)	2002-10-29
AU6380198A (en)	1998-11-05
JP3010153B2 (ja)	2000-02-14

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DE69802615D1 (de)	2002-01-10	Triaromatische Verbindungen, diese enthaltende Zusammensetzungen sowie ihre Anwendungen
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IT1303208B1 (it)	2000-10-30	Dispositivo per la sicurezza personale.
BRPI0511165A (pt)	2007-12-04	uso de sulglicotìdeo
FR2816504B1 (fr)	2003-04-18	Compositions comprenant au moins une glycosidase, lesdites compositions ne comprenant pas de protease
ES2185154T3 (es)	2003-04-16	Metodo de uso de inhibidores de la ciclooxigenasa-2 en el tratamiento y prevencion de la demencia.
NL1003501A1 (nl)	1996-08-16	Sexhulpmiddel.
TR199902914T2 (xx)	2000-06-21	�zole sistolik hipertansiyonu tedavi y�ntemi.
IT248611Y1 (it)	2003-02-06	Cancello o portone di sicurezza anticaduta.