[go: up one dir, main page]

DK0844245T3 - Benzopyranderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger, der indeholder disse - Google Patents

Benzopyranderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger, der indeholder disse

Info

Publication number
DK0844245T3
DK0844245T3 DK97402821T DK97402821T DK0844245T3 DK 0844245 T3 DK0844245 T3 DK 0844245T3 DK 97402821 T DK97402821 T DK 97402821T DK 97402821 T DK97402821 T DK 97402821T DK 0844245 T3 DK0844245 T3 DK 0844245T3
Authority
DK
Denmark
Prior art keywords
alkyl
optionally substituted
alkoxycarbonyl
processes
preparation
Prior art date
Application number
DK97402821T
Other languages
Danish (da)
English (en)
Inventor
Timothee Muller
Alain Tonnerre
Sylvie Robert-Piessard
Pierre Renard
Daniel-Henri Caignard
Claudie Moulin
Muriel Duflos
Baut Guillaume Le
Dominique Manechez
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0844245T3 publication Critical patent/DK0844245T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/723,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK97402821T 1996-11-26 1997-11-24 Benzopyranderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger, der indeholder disse DK0844245T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614470A FR2756284B1 (fr) 1996-11-26 1996-11-26 Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK0844245T3 true DK0844245T3 (da) 2001-06-11

Family

ID=9498038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97402821T DK0844245T3 (da) 1996-11-26 1997-11-24 Benzopyranderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger, der indeholder disse

Country Status (19)

Country Link
US (1) US5889045A (zh)
EP (1) EP0844245B1 (zh)
JP (1) JPH10158260A (zh)
CN (1) CN1183412A (zh)
AT (1) ATE201020T1 (zh)
AU (1) AU720479B2 (zh)
BR (1) BR9705064A (zh)
CA (1) CA2222467C (zh)
DE (1) DE69704755T2 (zh)
DK (1) DK0844245T3 (zh)
ES (1) ES2157539T3 (zh)
FR (1) FR2756284B1 (zh)
GR (1) GR3036242T3 (zh)
HU (1) HUP9702227A3 (zh)
NO (1) NO975402L (zh)
NZ (1) NZ329264A (zh)
PL (1) PL323339A1 (zh)
PT (1) PT844245E (zh)
ZA (1) ZA9710649B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU745081B2 (en) * 1997-06-27 2002-03-14 Fujisawa Pharmaceutical Co., Ltd. Sulfonamide compounds and medicinal use thereof
WO1999043315A1 (fr) * 1998-02-25 1999-09-02 Shionogi & Co., Ltd. Agent therapeutique utilisable en cas de complication de diabetes
KR100352986B1 (ko) * 2000-04-28 2002-09-18 주식회사 태평양 세라미드 유사 화합물 및 이의 제조방법, 및 이를함유하는 화장료 조성물
WO2004076437A1 (fr) * 2003-02-26 2004-09-10 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Composes de benzopyrane, leur procede de preparation et leurs utilisations
AU2006292352B2 (en) * 2005-09-16 2012-02-09 Cornell Research Foundation, Inc. Methods for reducing CD36 expression
PL2220030T3 (pl) * 2007-11-06 2016-07-29 Bioelectron Tech Corp Pochodne 4-(p-chinonylo)-2-hydroksybutanamidu do leczenia chorób mitochondrialnych
PT3297625T (pt) 2015-05-22 2022-09-27 Sulfateq Bv Composto para a profilaxia ou tratamento de nefropatia diabética ou doença renal diabética
TW201831471A (zh) 2017-02-24 2018-09-01 盧森堡商艾伯維公司 囊腫纖化症跨膜傳導調節蛋白的調節劑及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2087423A1 (en) * 1990-07-25 1992-01-26 Tatsuki Shiota Benzopyran derivative, process for producing the same and pharmaceutical composition containing the same
FR2676056B1 (fr) * 1991-05-03 1993-07-16 Adir Nouveaux derives du benzopyranne leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
KR950009863B1 (ko) * 1991-05-22 1995-08-29 재단법인한국화학연구소 벤조피란 유도체와 그의 제조방법
TW244350B (zh) * 1991-12-14 1995-04-01 Hoechst Ag
ZA93436B (en) * 1992-01-24 1993-08-25 Chugai Pharmaceutical Co Ltd Benzopyran derivatives
US5236935A (en) * 1992-05-21 1993-08-17 Korea Research Institute Of Chemical Technology Benzopyran derivatives and processes for the preparation thereof
US5516917A (en) * 1994-06-08 1996-05-14 G. D. Searle & Co. Leukotriene B4 antagonists
ES2169102T3 (es) * 1994-10-14 2002-07-01 Merck Patent Gmbh (r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano como agente activo sobre el sistema nervioso central.
FR2733685B1 (fr) * 1995-05-05 1997-05-30 Adir Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate

Also Published As

Publication number Publication date
NO975402D0 (no) 1997-11-25
CN1183412A (zh) 1998-06-03
FR2756284A1 (fr) 1998-05-29
HUP9702227A3 (en) 1999-03-01
HU9702227D0 (en) 1998-01-28
US5889045A (en) 1999-03-30
ATE201020T1 (de) 2001-05-15
CA2222467A1 (fr) 1998-05-26
AU4538397A (en) 1998-05-28
NO975402L (no) 1998-05-27
EP0844245A1 (fr) 1998-05-27
PT844245E (pt) 2001-09-28
NZ329264A (en) 1998-04-27
ES2157539T3 (es) 2001-08-16
HUP9702227A2 (hu) 1998-12-28
BR9705064A (pt) 1999-07-20
PL323339A1 (en) 1998-06-08
ZA9710649B (en) 1998-06-12
GR3036242T3 (en) 2001-10-31
FR2756284B1 (fr) 2000-04-28
EP0844245B1 (fr) 2001-05-09
JPH10158260A (ja) 1998-06-16
AU720479B2 (en) 2000-06-01
CA2222467C (fr) 2002-05-28
DE69704755D1 (de) 2001-06-13
DE69704755T2 (de) 2002-02-28

Similar Documents

Publication Publication Date Title
DK0485045T3 (da) Mono-N-substituerede 1,4,7,10-tetraazacyclododecanderivater, fremgangsmåde til fremstilling deraf samt farmaceutiske midler
ES2128013T3 (es) Nuevos derivados de la piperidina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
BRPI9908319B1 (pt) composto amino cìclico, composição farmacêutica, medicamento contendo um composto amino cìclico ou um sal farmacologicamente aceitável do mesmo, e, uso de um composto amino cìclico ou um sal farmacologicamente aceitável do mesmo.
DE69015147D1 (de) Verbesserungen in und bezüglich Angiotensin-II-Antagonisten.
EA200000391A1 (ru) Производные тиенопиримидина и тиенопиридина, полезные в качестве противораковых агентов
NO308848B1 (no) Kromanforbindelse og farmasøytisk preparat som inneholder den
ATE163182T1 (de) Salze eines indolderivates als anti-migraine mittel
BR9803295A (pt) preparos e composições farmacêuticas contendo os mesmos.
ATE226574T1 (de) 4,6-diarylpyrimidin-derivate und deren salze
DE69313051D1 (de) Ethanolamin-derivate mit sympathomimetischer und anti-pollakiuria wirkung
DK0844245T3 (da) Benzopyranderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger, der indeholder disse
ATE136025T1 (de) Dipeptidderivate und sie enthaltende prophylaktische und therapeutische mittel für knochenkrankheiten
NO982921D0 (no) Nye kromenforbindelser, en fremgangsmÕte for deres fremstilling og farmas°ytiske sammensetninger som inneholder disse
ATE202564T1 (de) Aminomethylheterozyclischederivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
KR950702953A (ko) 플루오레논 유도체, 이의 제조방법, 및 변성된 중추 또는 말초신경 복구제 및 중추 또는 말초신경 보호제(Fluorenone derivatives, process for preparing the same and central or peripheral nerve degeneration repair and protective agent)
DK1010693T3 (da) Nye imidazolinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
TNSN95099A1 (fr) Derives d'acides quinolone et naphtyridone-carboxyliques
DE69526595D1 (de) Pyridoncarbonsäurederivate substituiert von bicyclischer aminogruppe, deren ester und salze, und bicyclisches amin als zwischenprodukt davon
ATE212634T1 (de) Metalloproteaseinhibitoren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
FI970318A0 (fi) Antiproliferatiivisina aineina ja Garft-inhibiitoreina käyttökelpoisia yhdisteitä
PT955310E (pt) Novos derivados do acido (3,4,7,8,9,10)-hexa-hidro-6,10-dioxo-6h-piridazino[1,2-a] [1,2]diazepina-1-carboxilico, seu metodo de preaparacaoe sua aplicacao na preparacao de medicamentos
ATE228359T1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
DE69231244D1 (de) Pyrazolothiazolopyrimidin-derivate
ATE204582T1 (de) Von neurokininen abgeleitete pseudopeptide, verfahren für ihre herstellung und sie enthaltende pharmazeutische zubereitungen
HUP9902678A2 (hu) Protein kináz-C inhibitor hatású, halogénatommal szubsztituált bisz(indol)-maleinmid-származékok, valamint ezeket tartalmazó gyógyászati készítmények