DK0828721T3 - 2-Aminobenzoxazinoner til behandling af virale infektioner - Google Patents

2-Aminobenzoxazinoner til behandling af virale infektioner

Info

Publication number: DK0828721T3
Authority: DK; Denmark
Prior art keywords: treatment; viral infections; aminobenzoxazinones; compounds; pharmaceutically
Prior art date: 1995-05-24

Application number

DK96914762T

Other languages

Danish (da)

English (en)

Inventor

Daniel L Flynn

Clara I Villamil

Roger A Nosal

Norman Abood

Daniel P Becker

Brian M Bax

Hui Li

Lori A Schretzman

Michael J Bennett

John L Bedell

Kenneth Williams

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-24

Filing date

1996-05-23

Publication date

2002-03-04

1996-05-23 Application filed by Searle & Co filed Critical Searle & Co

2000-02-11 Priority claimed from US09/502,038 external-priority patent/US6380189B1/en

2002-03-04 Application granted granted Critical

2002-03-04 Publication of DK0828721T3 publication Critical patent/DK0828721T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK96914762T 1995-05-24 1996-05-23 2-Aminobenzoxazinoner til behandling af virale infektioner DK0828721T3 (da)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US08/448,795 US5985872A (en)	1995-05-24	1995-05-24	2-amino-benzoxazinones for the treatment of viral infections
PCT/US1996/007526 WO1996037485A1 (en)	1995-05-24	1996-05-23	2-amino-benzoxazinones for the treatment of viral infections
US95262498A	1998-05-15	1998-05-15
US09/502,038 US6380189B1 (en)	1995-05-24	2000-02-11	2-amino benzoxazinones for the treatment of viral infections
US10/035,433 US6683077B2 (en)	1995-05-24	2002-01-04	2-Amino-benzoxazinones for the treatment of viral infections

Publications (1)

Publication Number	Publication Date
DK0828721T3 true DK0828721T3 (da)	2002-03-04

Family

ID=37772666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96914762T DK0828721T3 (da)	1995-05-24	1996-05-23	2-Aminobenzoxazinoner til behandling af virale infektioner

Country Status (15)

Country	Link
US (3)	US5985872A (de)
EP (1)	EP0828721B1 (de)
JP (1)	JPH11505849A (de)
CN (1)	CN1070480C (de)
AT (2)	ATE208765T1 (de)
AU (1)	AU711174B2 (de)
BR (1)	BR9608506A (de)
CA (1)	CA2222034A1 (de)
DE (2)	DE69617005T2 (de)
DK (1)	DK0828721T3 (de)
ES (2)	ES2225339T3 (de)
NZ (1)	NZ308398A (de)
PT (2)	PT1122245E (de)
TW (1)	TW455583B (de)
WO (1)	WO1996037485A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5985872A (en) *	1995-05-24	1999-11-16	G.D. Searle & Co.	2-amino-benzoxazinones for the treatment of viral infections
KR100460932B1 (ko) *	1995-05-24	2005-02-28	지.디. 썰 엘엘씨	바이러스감염치료용2-아미노-벤조옥사진온
AU3339797A (en) *	1996-06-20	1998-01-07	Smithkline Beecham Plc	4h-3,1-benzoxazin-4-one derivatives and analogs as antiviral agents
GB9710928D0 (en) *	1997-05-29	1997-07-23	Smithkline Beecham Plc	Pharmaceuticals
AR022204A1 (es) *	1999-01-08	2002-09-04	Norgine Bv	Compuesto, proceso para su preparacion, composicion farmaceutica y producto comestible que lo comprende.
GB9900416D0 (en)	1999-01-08	1999-02-24	Alizyme Therapeutics Ltd	Inhibitors
US6806269B1 (en) *	1999-07-12	2004-10-19	G. D. Searle & Cop	2-Amino-benzoxazinones for the treatment of herpes simplex virus
CA2378014A1 (en) *	1999-07-12	2001-01-18	G.D. Searle & Co.	2-amino-benzoxazinones for the treatment of herpes simplex virus
DE10036184A1 (de) *	2000-07-24	2002-02-14	Aventis Cropscience Gmbh	Substituierte Sulfonylaminomethylbenzoesäure(derivate) und Verfahren zu ihrer Herstellung
WO2003002558A1 (fr) *	2001-06-13	2003-01-09	Asahi Kasei Pharma Corporation	Remede pour maladies infectieuses virales
EP1565429B1 (de) *	2002-11-21	2009-05-13	Neurosearch A/S	Diarylureidoderivate und deren medizinische verwendung
US7192471B2 (en) *	2004-09-24	2007-03-20	Honeywell International Inc.	Aryl-ureido benzoxazinone compounds
EP2103601B1 (de)	2006-11-22	2012-03-14	Ajinomoto Co., Inc.	Verfahren zur herstellung von phenylalaninderivaten mit chinazolindiongerüsten, und zwischenprodukte für die herstellung
JP2010525069A (ja) *	2007-04-27	2010-07-22	パラテックファーマシューティカルズインコーポレイテッド	アミノアルキルテトラサイクリン化合物の合成方法および精製方法
US8356971B2 (en) *	2009-12-17	2013-01-22	Detch John W	Disc turbine with streamlined hub vanes and co-axial exhaust tube
CN115109006B (zh) *	2022-05-20	2025-03-14	上海大学	一种3-取代-1,2-苯并噁嗪-4-酮类化合物的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3297755A (en) *	1960-12-02	1967-01-10	Hoffmann La Roche	2-chloro-5-trifluoromethylbenzo-phenone compounds
US3450700A (en) *	1966-12-20	1969-06-17	Upjohn Co	2-tertiary amino-4h-3,1-benzoxazin-4-ones
DE2218302A1 (de) *	1972-04-15	1973-10-25	Bayer Ag	Verfahren zur herstellung von trifluormethylimino-derivaten von benzoxazinonen
DE2315303A1 (de) *	1973-03-27	1974-10-17	Bayer Ag	Verfahren zur herstellung von n-substituierten 2-amino-3,1-benzoxazin-4-onen
NZ210669A (en) *	1983-12-27	1988-05-30	Syntex Inc	Benzoxazin-4-one derivatives and pharmaceutical compositions
US4657893A (en) *	1984-05-09	1987-04-14	Syntex (U.S.A.) Inc.	4H-3,1-benzoxazin-4-ones and related compounds and use as enzyme inhibitors
US4665070A (en) *	1985-06-25	1987-05-12	Syntex (U.S.A.) Inc.	2-oxy-4H-3,1-benzoxazin-4-ones and pharmaceutical use
US4745116A (en) *	1985-06-25	1988-05-17	Syntex (U.S.A.) Inc.	2-oxy-4H-3,1-benzoxazin-4-ones and related compounds and pharmaceutical use
CA1309556C (en) *	1987-06-09	1992-10-27	Masayuki Kokubo	4h-3,1-benzoxazin-4-one compounds and pharmaceutical composition thereoffor the inhibition of serine proteases
JP2685648B2 (ja) *	1990-02-15	1997-12-03	帝人株式会社	４ｈ−３．１−ベンズオキサジン−４−オン化合物
CA2084997A1 (en) *	1991-04-10	1992-10-11	Koji Kobayashi	Oxazinone derivative
NZ242739A (en) *	1991-05-24	1994-12-22	Arch Dev Corp	Identification and purification of herpes protease nucleic acid segments and their use in the production of this protease
US5434074A (en) *	1991-07-05	1995-07-18	Gibson; D. Wade	Cytomegalovirus proteinase
US5428021A (en) *	1994-01-27	1995-06-27	Sri International	Human leukocyte elastase (HLE) inhibitors, and related pharmaceutical compositions and methods of use
US5652237A (en) *	1994-09-09	1997-07-29	Warner-Lambert Company	2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes
KR100460932B1 (ko) *	1995-05-24	2005-02-28	지.디. 썰 엘엘씨	바이러스감염치료용2-아미노-벤조옥사진온
US5985872A (en) *	1995-05-24	1999-11-16	G.D. Searle & Co.	2-amino-benzoxazinones for the treatment of viral infections

1995
- 1995-05-24 US US08/448,795 patent/US5985872A/en not_active Expired - Fee Related
1996
- 1996-05-23 PT PT01110048T patent/PT1122245E/pt unknown
- 1996-05-23 CN CN96195622A patent/CN1070480C/zh not_active Expired - Fee Related
- 1996-05-23 AU AU58030/96A patent/AU711174B2/en not_active Ceased
- 1996-05-23 WO PCT/US1996/007526 patent/WO1996037485A1/en active IP Right Grant
- 1996-05-23 ES ES01110048T patent/ES2225339T3/es not_active Expired - Lifetime
- 1996-05-23 JP JP8535869A patent/JPH11505849A/ja not_active Abandoned
- 1996-05-23 NZ NZ308398A patent/NZ308398A/xx unknown
- 1996-05-23 BR BR9608506A patent/BR9608506A/pt not_active Application Discontinuation
- 1996-05-23 ES ES96914762T patent/ES2169242T3/es not_active Expired - Lifetime
- 1996-05-23 DE DE69617005T patent/DE69617005T2/de not_active Expired - Fee Related
- 1996-05-23 EP EP96914762A patent/EP0828721B1/de not_active Expired - Lifetime
- 1996-05-23 AT AT96914762T patent/ATE208765T1/de not_active IP Right Cessation
- 1996-05-23 DK DK96914762T patent/DK0828721T3/da active
- 1996-05-23 PT PT96914762T patent/PT828721E/pt unknown
- 1996-05-23 AT AT01110048T patent/ATE270667T1/de not_active IP Right Cessation
- 1996-05-23 DE DE69632876T patent/DE69632876T2/de not_active Expired - Fee Related
- 1996-05-23 CA CA002222034A patent/CA2222034A1/en not_active Abandoned
- 1996-10-08 TW TW085112293A patent/TW455583B/zh not_active IP Right Cessation
2002
- 2002-01-04 US US10/035,433 patent/US6683077B2/en not_active Expired - Fee Related
2003
- 2003-12-08 US US10/728,946 patent/US20050032793A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2222034A1 (en)	1996-11-28
NZ308398A (en)	1999-06-29
PT828721E (pt)	2002-04-29
DE69632876D1 (de)	2004-08-12
JPH11505849A (ja)	1999-05-25
EP0828721B1 (de)	2001-11-14
DE69632876T2 (de)	2005-03-03
PT1122245E (pt)	2004-11-30
BR9608506A (pt)	1999-06-15
ES2169242T3 (es)	2002-07-01
AU711174B2 (en)	1999-10-07
CN1190963A (zh)	1998-08-19
ATE270667T1 (de)	2004-07-15
US6683077B2 (en)	2004-01-27
US5985872A (en)	1999-11-16
ATE208765T1 (de)	2001-11-15
US20050032793A1 (en)	2005-02-10
US20030022895A1 (en)	2003-01-30
DE69617005D1 (de)	2001-12-20
AU5803096A (en)	1996-12-11
CN1070480C (zh)	2001-09-05
DE69617005T2 (de)	2002-07-04
ES2225339T3 (es)	2005-03-16
EP0828721A1 (de)	1998-03-18
WO1996037485A1 (en)	1996-11-28
TW455583B (en)	2001-09-21

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ES2172864T3 (es)	2002-10-01	2-metoxibenzofenonas fungicidas.
DK0828721T3 (da)	2002-03-04	2-Aminobenzoxazinoner til behandling af virale infektioner
ATE206409T1 (de)	2001-10-15	N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h- benzo(b)(1,5)-diazepin-3-yl)-acetamide
BR9900177A (pt)	2000-04-11	Inibidores de metaloprotease.
NO920767L (no)	1992-08-28	Pyranylcyanoguanidin-derivater
EA200201083A1 (ru)	2003-04-24	Противоопухолевые производные эктейнасцидина
ES2193241T3 (es)	2003-11-01	Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
DK0903347T3 (da)	2005-11-21	Hidtil ukendte cyclodepsipeptid PF1022-derivater
TR200002932T2 (tr)	2001-01-22	Azabisayklik 5HT1 Alıcı liganolları
ES2194102T3 (es)	2003-11-16	Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
TR200302288T2 (tr)	2004-12-21	Terapi için yeni bileşikler ve metotlar.
ATE250021T1 (de)	2003-10-15	Hydroxycyclopentanone
ES2181790T3 (es)	2003-03-01	Compuestos azaciclohexapeptidicos.
DK0915858T3 (da)	2000-11-20	Mellemprodukter til fremstilling af 2-imidazolin-5-oner
MX9709016A (es)	1998-04-30	2-amino-benzoxazinonas, composiciones que las contienen y uso de las mismas.
DK0779895T3 (da)	2000-03-13	Forbedret fremgangsmåde til fremstilling af sidekædederivater af cyclohexapeptidyl-lipopeptider
DK1178985T3 (da)	2003-07-28	Substituerede thienocycloalk(en)ylamino-1,3,5-triaziner
SE9602416D0 (sv)	1996-06-18	New forms of an organic salt of N'N-diacetylcystine
DK1140932T3 (da)	2004-07-05	Derivater af benzo-1,8-naphtyridin
ES2195309T3 (es)	2003-12-01	Derivados de tetrahidrofurano.
DE60108242D1 (de)	2005-02-10	Herstellung von hydroxyverbindungen