DK0799239T3 - Diastereomert rene 3-oxo- og 3-thioxo-4-aza-androstan-derivater og anvendelse deraf som antiandrogener - Google Patents
Diastereomert rene 3-oxo- og 3-thioxo-4-aza-androstan-derivater og anvendelse deraf som antiandrogenerInfo
- Publication number
- DK0799239T3 DK0799239T3 DK95942689T DK95942689T DK0799239T3 DK 0799239 T3 DK0799239 T3 DK 0799239T3 DK 95942689 T DK95942689 T DK 95942689T DK 95942689 T DK95942689 T DK 95942689T DK 0799239 T3 DK0799239 T3 DK 0799239T3
- Authority
- DK
- Denmark
- Prior art keywords
- antiandrogens
- thioxo
- aza
- oxo
- diastereomerically pure
- Prior art date
Links
- 239000000051 antiandrogen Substances 0.000 title abstract 2
- YNUIDWIWRVBIMB-RIMFYDMWSA-N (3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,5a,6,8,9,9b,10,11-tetradecahydroindeno[5,4-f]quinoline-7-thione Chemical class S=C1N[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(CCC[C@H]43)C)[C@]2(CC1)C YNUIDWIWRVBIMB-RIMFYDMWSA-N 0.000 title 1
- 230000002280 anti-androgenic effect Effects 0.000 title 1
- 229940030495 antiandrogen sex hormone and modulator of the genital system Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI942626A IT1271325B (it) | 1994-12-23 | 1994-12-23 | Composti diastereomericamente puri derivati da 3-oxo e 3-tioxo-4-azaandrostani e loro uso come antiandrogeni |
| PCT/EP1995/005008 WO1996020210A2 (en) | 1994-12-23 | 1995-12-18 | Diastereomerically pure 3-oxo and 3-thioxo-4-aza-androstan derivatives and the use thereof as antiandrogens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0799239T3 true DK0799239T3 (da) | 2001-12-10 |
Family
ID=11370067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95942689T DK0799239T3 (da) | 1994-12-23 | 1995-12-18 | Diastereomert rene 3-oxo- og 3-thioxo-4-aza-androstan-derivater og anvendelse deraf som antiandrogener |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6147213A (da) |
| EP (1) | EP0799239B1 (da) |
| AT (1) | ATE207929T1 (da) |
| AU (1) | AU4387296A (da) |
| DE (1) | DE69523622T2 (da) |
| DK (1) | DK0799239T3 (da) |
| ES (1) | ES2163538T3 (da) |
| IT (1) | IT1271325B (da) |
| PT (1) | PT799239E (da) |
| WO (1) | WO1996020210A2 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
| EP2100317B1 (en) | 2006-11-15 | 2016-01-27 | Energ2, Inc. | Electric double layer capacitance device |
| US8552061B2 (en) * | 2007-05-03 | 2013-10-08 | Yale University | Locally active “soft” antiandrogens |
| HRP20241382T1 (hr) | 2009-07-01 | 2024-12-20 | Basf Mobile Emissions Catalysts Llc | Ultračisti sintetički ugljični materijali |
| EP2510569B1 (en) * | 2009-12-11 | 2020-07-22 | Basf Se | Carbon materials comprising an electrochemical modifier |
| WO2011112992A1 (en) | 2010-03-12 | 2011-09-15 | Energ2, Inc. | Mesoporous carbon materials comprising bifunctional catalysts |
| US8654507B2 (en) | 2010-09-30 | 2014-02-18 | Energ2 Technologies, Inc. | Enhanced packing of energy storage particles |
| CN103370756B (zh) | 2010-12-28 | 2018-05-11 | 巴斯福股份公司 | 包含增强的电化学特性的碳材料 |
| US20120262127A1 (en) | 2011-04-15 | 2012-10-18 | Energ2 Technologies, Inc. | Flow ultracapacitor |
| EP2715840B1 (en) | 2011-06-03 | 2015-05-27 | Basf Se | Carbon-lead blends for use in hybrid energy storage devices |
| WO2013120011A1 (en) | 2012-02-09 | 2013-08-15 | Energ2 Technologies, Inc. | Preparation of polymeric resins and carbon materials |
| CN110112377A (zh) | 2013-03-14 | 2019-08-09 | 14族科技公司 | 包含锂合金化的电化学改性剂的复合碳材料 |
| US10195583B2 (en) | 2013-11-05 | 2019-02-05 | Group 14 Technologies, Inc. | Carbon-based compositions with highly efficient volumetric gas sorption |
| CN107074994B (zh) | 2014-03-14 | 2021-12-14 | 14集团技术公司 | 无溶剂进行溶胶-凝胶聚合并由其产生可调节的碳结构的新方法 |
| US10763501B2 (en) | 2015-08-14 | 2020-09-01 | Group14 Technologies, Inc. | Nano-featured porous silicon materials |
| EP3836261A1 (en) | 2015-08-28 | 2021-06-16 | Group14 Technologies, Inc. | Novel materials with extremely durable intercalation of lithium and manufacturing methods thereof |
| CN116978701A (zh) | 2017-03-09 | 2023-10-31 | 14集团技术公司 | 含硅前体在多孔支架材料上的分解 |
| US11639292B2 (en) | 2020-08-18 | 2023-05-02 | Group14 Technologies, Inc. | Particulate composite materials |
| US11174167B1 (en) | 2020-08-18 | 2021-11-16 | Group14 Technologies, Inc. | Silicon carbon composites comprising ultra low Z |
| US11335903B2 (en) | 2020-08-18 | 2022-05-17 | Group14 Technologies, Inc. | Highly efficient manufacturing of silicon-carbon composites materials comprising ultra low z |
| JP2023544717A (ja) | 2020-09-30 | 2023-10-25 | グループ１４・テクノロジーズ・インコーポレイテッド | シリコン－カーボン複合材料の酸素含有量及び反応性制御のための不動態化の方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845104A (en) * | 1986-11-20 | 1989-07-04 | Merck & Co., Inc. | Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones |
| IE76452B1 (en) * | 1990-10-29 | 1997-10-22 | Sankyo Co | Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use |
| GB9216329D0 (en) * | 1992-07-31 | 1992-09-16 | Erba Carlo Spa | 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives |
-
1994
- 1994-12-23 IT ITMI942626A patent/IT1271325B/it active IP Right Grant
-
1995
- 1995-12-18 AU AU43872/96A patent/AU4387296A/en not_active Abandoned
- 1995-12-18 US US08/879,442 patent/US6147213A/en not_active Expired - Lifetime
- 1995-12-18 DE DE69523622T patent/DE69523622T2/de not_active Expired - Lifetime
- 1995-12-18 AT AT95942689T patent/ATE207929T1/de active
- 1995-12-18 EP EP95942689A patent/EP0799239B1/en not_active Expired - Lifetime
- 1995-12-18 PT PT95942689T patent/PT799239E/pt unknown
- 1995-12-18 WO PCT/EP1995/005008 patent/WO1996020210A2/en active IP Right Grant
- 1995-12-18 DK DK95942689T patent/DK0799239T3/da active
- 1995-12-18 ES ES95942689T patent/ES2163538T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2163538T3 (es) | 2002-02-01 |
| ITMI942626A0 (it) | 1994-12-23 |
| ITMI942626A1 (it) | 1996-06-23 |
| AU4387296A (en) | 1996-07-19 |
| EP0799239A2 (en) | 1997-10-08 |
| DE69523622T2 (de) | 2002-05-29 |
| IT1271325B (it) | 1997-05-27 |
| DE69523622D1 (de) | 2001-12-06 |
| WO1996020210A2 (en) | 1996-07-04 |
| US6147213A (en) | 2000-11-14 |
| WO1996020210A3 (en) | 1996-09-06 |
| ATE207929T1 (de) | 2001-11-15 |
| EP0799239B1 (en) | 2001-10-31 |
| PT799239E (pt) | 2002-02-28 |
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