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DK0797997T3 - Anvendelse af peptidiske bradykinin-antagonister til fremstilling af lægemidler - Google Patents

Anvendelse af peptidiske bradykinin-antagonister til fremstilling af lægemidler

Info

Publication number
DK0797997T3
DK0797997T3 DK97104345T DK97104345T DK0797997T3 DK 0797997 T3 DK0797997 T3 DK 0797997T3 DK 97104345 T DK97104345 T DK 97104345T DK 97104345 T DK97104345 T DK 97104345T DK 0797997 T3 DK0797997 T3 DK 0797997T3
Authority
DK
Denmark
Prior art keywords
drugs
manufacture
bradykinin antagonists
peptidic bradykinin
liver
Prior art date
Application number
DK97104345T
Other languages
Danish (da)
English (en)
Inventor
Gerhard Breipohl
Stephan Henke
Jochen Knolle
Klaus Wirth
Max Hropot
Martin Bickel
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK0797997T3 publication Critical patent/DK0797997T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97104345T 1996-03-27 1997-03-14 Anvendelse af peptidiske bradykinin-antagonister til fremstilling af lægemidler DK0797997T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19612067A DE19612067A1 (de) 1996-03-27 1996-03-27 Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
EP97104345A EP0797997B1 (de) 1996-03-27 1997-03-14 Verwendung von peptidischen Bradykinin-Antagonisten zur Herstellung von Arzneimitteln

Publications (1)

Publication Number Publication Date
DK0797997T3 true DK0797997T3 (da) 2005-10-17

Family

ID=7789557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97104345T DK0797997T3 (da) 1996-03-27 1997-03-14 Anvendelse af peptidiske bradykinin-antagonister til fremstilling af lægemidler

Country Status (24)

Country Link
US (1) US5863901A (zh)
EP (1) EP0797997B1 (zh)
JP (1) JP4185169B2 (zh)
KR (1) KR100453394B1 (zh)
CN (1) CN1164421A (zh)
AT (1) ATE297749T1 (zh)
AU (1) AU1651697A (zh)
BR (1) BR9701455A (zh)
CA (1) CA2200040A1 (zh)
CZ (1) CZ90797A3 (zh)
DE (2) DE19612067A1 (zh)
DK (1) DK0797997T3 (zh)
ES (1) ES2242973T3 (zh)
HR (1) HRP970171A2 (zh)
HU (1) HUP9700642A3 (zh)
ID (1) ID16413A (zh)
IL (1) IL120521A0 (zh)
NO (1) NO971453L (zh)
PL (1) PL319193A1 (zh)
PT (1) PT797997E (zh)
SI (1) SI0797997T1 (zh)
SK (1) SK39297A3 (zh)
TR (1) TR199700228A2 (zh)
ZA (1) ZA972599B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914236A1 (en) 2002-04-10 2008-04-23 Ortho-McNeil Pharmaceutical, Inc. Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators
TWI407960B (zh) 2007-03-23 2013-09-11 Jerini Ag 小分子緩激肽ｂ２受體調節劑
JP2011525194A (ja) * 2008-06-20 2011-09-15 キネメッド， インコーポレイテッド 線維性疾患または病態を治療するための組成物
SMT202200154T1 (it) 2017-11-24 2022-05-12 Pharvaris Netherlands B V Nuovi antagonisti del recettore della bradichinina b2
UY38706A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina
UY38707A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Nuevos antagonistas cíclicos del receptor b2 de bradiquinina

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
WO1989009230A1 (en) * 1988-03-25 1989-10-05 Administrators Of The Tulane Educational Fund Therapeutic peptides
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
EP0502987B1 (en) * 1989-12-08 1994-08-31 Trustees Of Boston University Acylated bradykinin antagonists and uses therefor
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
CZ203693A3 (en) * 1991-04-01 1994-07-13 Cortech Bradykinin antagonists
CA2106762C (en) * 1991-04-19 2000-10-10 Donald J. Kyle Bradykinin antagonist peptides
ES2123556T3 (es) * 1991-04-19 1999-01-16 Scios Nova Inc Peptidos de tipo bradiquinina.
WO1993011789A1 (en) * 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
FR2686343B1 (fr) * 1992-01-17 1994-03-11 Adir Cie Nouveaux derives pseudopeptidiques a activite antagoniste de la bradykinine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW258739B (zh) * 1992-04-04 1995-10-01 Hoechst Ag
FR2692581B1 (fr) * 1992-06-18 1994-08-19 Adir Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO1994006453A1 (en) * 1992-09-11 1994-03-31 Stewart John M Bradykinin antagonists containing aliphatic amino acids in the 5-position
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
IL107400A0 (en) * 1992-11-10 1994-01-25 Cortech Inc Bradykinin antagonists
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
AU680870B2 (en) * 1993-04-28 1997-08-14 Astellas Pharma Inc. New heterocyclic compounds
JPH11500100A (ja) * 1993-09-09 1999-01-06 サイオス ノバ インコーポレイテッド 偽ペプチドおよび非ペプチドブラジキニンレセプターアンタゴニスト
DE4345062A1 (de) * 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
DE69533704D1 (de) * 1994-03-09 2004-12-02 Cortech Inc Bradykinin-antagonist peptide mit n-substituierten glycinen

Also Published As

Publication number Publication date
KR970064622A (ko) 1997-10-13
MX9702292A (es) 1997-09-30
CN1164421A (zh) 1997-11-12
SI0797997T1 (en) 2005-10-31
JP4185169B2 (ja) 2008-11-26
NO971453L (no) 1997-09-29
IL120521A0 (en) 1997-07-13
PL319193A1 (en) 1997-09-29
AU1651697A (en) 1997-10-02
HUP9700642A3 (en) 1998-03-02
HU9700642D0 (en) 1997-05-28
TR199700228A2 (xx) 1997-10-21
HUP9700642A2 (hu) 1998-01-28
ZA972599B (en) 1997-09-29
CZ90797A3 (en) 1997-10-15
ID16413A (id) 1997-09-25
JPH1017491A (ja) 1998-01-20
KR100453394B1 (ko) 2004-12-30
EP0797997A3 (de) 2000-05-31
CA2200040A1 (en) 1997-09-27
EP0797997B1 (de) 2005-06-15
ES2242973T3 (es) 2005-11-16
PT797997E (pt) 2005-09-30
SK39297A3 (en) 1997-10-08
HRP970171A2 (en) 1998-04-30
NO971453D0 (no) 1997-03-26
DE19612067A1 (de) 1997-10-02
BR9701455A (pt) 1998-08-18
DE59712344D1 (de) 2005-07-21
US5863901A (en) 1999-01-26
ATE297749T1 (de) 2005-07-15
EP0797997A2 (de) 1997-10-01

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