DK0765876T3 - Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolacton - Google Patents
Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolactonInfo
- Publication number
- DK0765876T3 DK0765876T3 DK96111567T DK96111567T DK0765876T3 DK 0765876 T3 DK0765876 T3 DK 0765876T3 DK 96111567 T DK96111567 T DK 96111567T DK 96111567 T DK96111567 T DK 96111567T DK 0765876 T3 DK0765876 T3 DK 0765876T3
- Authority
- DK
- Denmark
- Prior art keywords
- butyrolactone
- gamma
- beta
- hydroxy
- preparation
- Prior art date
Links
- FUDDLSHBRSNCBV-UHFFFAOYSA-N (+)-(R)-3-hydroxytetrahydrofuranone Natural products OC1COC(=O)C1 FUDDLSHBRSNCBV-UHFFFAOYSA-N 0.000 title abstract 2
- FUDDLSHBRSNCBV-VKHMYHEASA-N (4s)-4-hydroxyoxolan-2-one Chemical compound O[C@@H]1COC(=O)C1 FUDDLSHBRSNCBV-VKHMYHEASA-N 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
- 229960001518 levocarnitine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Seasonings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95RM000652A IT1276207B1 (it) | 1995-09-29 | 1995-09-29 | Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0765876T3 true DK0765876T3 (da) | 1999-08-16 |
Family
ID=11403592
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96111567T DK0765876T3 (da) | 1995-09-29 | 1996-07-18 | Fremgangsmåde til fremstilling af (S)-beta-hydroxy-gamma-butyrolacton |
Country Status (12)
Country | Link |
---|---|
US (1) | US5714619A (da) |
EP (1) | EP0765876B1 (da) |
JP (1) | JP4012588B2 (da) |
KR (1) | KR100407645B1 (da) |
AT (1) | ATE174333T1 (da) |
CA (1) | CA2181012A1 (da) |
DE (1) | DE69601116T2 (da) |
DK (1) | DK0765876T3 (da) |
ES (1) | ES2126969T3 (da) |
GR (1) | GR3029537T3 (da) |
IT (1) | IT1276207B1 (da) |
ZA (1) | ZA968127B (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1297120B1 (it) * | 1997-12-16 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina |
EP1055654B1 (en) * | 1998-12-11 | 2008-02-20 | Daicel Chemical Industries, Ltd. | Process for the preparation of organic compounds with imide catalysts |
KR20000065995A (ko) * | 1999-04-12 | 2000-11-15 | 박영구 | 키랄 3-히드록시-γ-부티로락톤의 제조방법 |
CN104961711B (zh) * | 2015-07-23 | 2017-03-08 | 沧州那瑞化学科技有限公司 | (s)‑3‑羟基四氢呋喃和(r)‑3‑羟基四氢呋喃的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3087325B2 (ja) * | 1991-02-21 | 2000-09-11 | チッソ株式会社 | 光学活性化合物とその製造法 |
IT1256705B (it) * | 1992-12-21 | 1995-12-12 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
IT1261231B (it) * | 1993-04-08 | 1996-05-09 | Sigma Tau Ind Farmaceuti | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
IT1261230B (it) * | 1993-04-08 | 1996-05-09 | Sigma Tau Ind Farmaceuti | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione. |
IT1261489B (it) * | 1993-07-29 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r amminocarnitina e s amminocarnitina. |
US5473104A (en) * | 1994-09-13 | 1995-12-05 | Neurocrine Biosciences, Inc. | Process for the preparation of L-carnitine |
-
1995
- 1995-09-29 IT IT95RM000652A patent/IT1276207B1/it active IP Right Grant
-
1996
- 1996-07-11 US US08/678,684 patent/US5714619A/en not_active Expired - Fee Related
- 1996-07-11 CA CA002181012A patent/CA2181012A1/en not_active Abandoned
- 1996-07-18 AT AT96111567T patent/ATE174333T1/de not_active IP Right Cessation
- 1996-07-18 ES ES96111567T patent/ES2126969T3/es not_active Expired - Lifetime
- 1996-07-18 DE DE69601116T patent/DE69601116T2/de not_active Expired - Fee Related
- 1996-07-18 DK DK96111567T patent/DK0765876T3/da active
- 1996-07-18 EP EP96111567A patent/EP0765876B1/en not_active Expired - Lifetime
- 1996-07-23 KR KR1019960029667A patent/KR100407645B1/ko not_active Expired - Fee Related
- 1996-08-01 JP JP20355396A patent/JP4012588B2/ja not_active Expired - Fee Related
- 1996-09-27 ZA ZA968127A patent/ZA968127B/xx unknown
-
1999
- 1999-03-01 GR GR990400632T patent/GR3029537T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0765876A1 (en) | 1997-04-02 |
KR970015583A (ko) | 1997-04-28 |
ES2126969T3 (es) | 1999-04-01 |
ATE174333T1 (de) | 1998-12-15 |
GR3029537T3 (en) | 1999-06-30 |
DE69601116T2 (de) | 1999-05-06 |
KR100407645B1 (ko) | 2004-03-18 |
JPH09110851A (ja) | 1997-04-28 |
DE69601116D1 (de) | 1999-01-21 |
JP4012588B2 (ja) | 2007-11-21 |
EP0765876B1 (en) | 1998-12-09 |
IT1276207B1 (it) | 1997-10-27 |
US5714619A (en) | 1998-02-03 |
ITRM950652A0 (da) | 1995-09-29 |
CA2181012A1 (en) | 1997-03-30 |
ITRM950652A1 (it) | 1997-03-29 |
ZA968127B (en) | 1997-04-21 |
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