DK0754050T3 - Anti-gram-positive bakterielle fremgangsmåder og materialer - Google Patents
Anti-gram-positive bakterielle fremgangsmåder og materialerInfo
- Publication number
- DK0754050T3 DK0754050T3 DK95908545T DK95908545T DK0754050T3 DK 0754050 T3 DK0754050 T3 DK 0754050T3 DK 95908545 T DK95908545 T DK 95908545T DK 95908545 T DK95908545 T DK 95908545T DK 0754050 T3 DK0754050 T3 DK 0754050T3
- Authority
- DK
- Denmark
- Prior art keywords
- gram
- materials
- positive bacterial
- protein product
- bpi protein
- Prior art date
Links
- 230000001580 bacterial effect Effects 0.000 title 1
- 102000052586 bactericidal permeability increasing protein Human genes 0.000 abstract 3
- 108010032816 bactericidal permeability increasing protein Proteins 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 208000027136 gram-positive bacterial infections Diseases 0.000 abstract 1
- 230000009422 growth inhibiting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18322294A | 1994-01-14 | 1994-01-14 | |
US08/209,762 US5733872A (en) | 1993-03-12 | 1994-03-11 | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
US27429994A | 1994-07-11 | 1994-07-11 | |
PCT/US1994/010427 WO1995019372A1 (en) | 1994-01-14 | 1994-09-15 | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
PCT/US1995/000656 WO1995019180A1 (en) | 1994-01-14 | 1995-01-13 | Anti-gram-positive bacterial methods and materials |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0754050T3 true DK0754050T3 (da) | 2002-10-21 |
Family
ID=27391655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95908545T DK0754050T3 (da) | 1994-01-14 | 1995-01-13 | Anti-gram-positive bakterielle fremgangsmåder og materialer |
Country Status (12)
Country | Link |
---|---|
US (3) | US5578572A (da) |
EP (1) | EP0754050B1 (da) |
JP (1) | JPH09508359A (da) |
AT (1) | ATE219684T1 (da) |
AU (1) | AU703192B2 (da) |
CA (1) | CA2181164C (da) |
DE (1) | DE69527195T2 (da) |
DK (1) | DK0754050T3 (da) |
ES (1) | ES2179095T3 (da) |
HK (1) | HK1014160A1 (da) |
PT (1) | PT754050E (da) |
WO (1) | WO1995019180A1 (da) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5652332A (en) * | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
PT754050E (pt) * | 1994-01-14 | 2002-11-29 | Xoma Technology Ltd | Metodos e materiais contra bacterias gram-positivas |
US5447913A (en) | 1994-03-11 | 1995-09-05 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
US5912228A (en) | 1995-01-13 | 1999-06-15 | Xoma Corporation | Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products |
CA2227292A1 (en) * | 1995-07-20 | 1997-02-06 | Xoma Corporation | Anti-fungal peptides |
WO1997042966A1 (en) * | 1996-05-10 | 1997-11-20 | Xoma Corporation | Therapeutic uses of bpi protein products for human meningococcemia |
US5741779A (en) | 1996-05-10 | 1998-04-21 | Xoma Corporation | Antithrombotic materials and methods |
ATE234111T1 (de) * | 1996-05-23 | 2003-03-15 | Xoma Technology Ltd | Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung |
US5888973A (en) | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
US6180604B1 (en) * | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
US6482796B2 (en) | 1996-11-01 | 2002-11-19 | Xoma Corporation | Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients |
US6093573A (en) * | 1997-06-20 | 2000-07-25 | Xoma | Three-dimensional structure of bactericidal/permeability-increasing protein (BPI) |
US6013631A (en) | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
WO2000018798A1 (en) * | 1998-09-25 | 2000-04-06 | Xoma Technology Ltd. | Antifungal and antibacterial peptide |
US7056893B2 (en) * | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
US6284517B1 (en) * | 1999-05-28 | 2001-09-04 | Lawrence Restaino | Plating media for the presumptive identification of Bacillus cereus and Bacillus thuringiensis |
WO2001081307A2 (en) * | 2000-04-26 | 2001-11-01 | Wisconsin Alumni Research Foundation | Triaryl cation antibiotics from environmental dna |
US7527807B2 (en) * | 2000-06-21 | 2009-05-05 | Cubist Pharmaceuticals, Inc. | Compositions and methods for increasing the oral absorption of antimicrobials |
EP1339424A2 (en) * | 2000-12-01 | 2003-09-03 | XOMA Technology Ltd. | Modulation of pericyte proliferation using bpi protein products or bpi inhibitors |
MY138797A (en) | 2000-12-15 | 2009-07-31 | Vertex Pharma | Bacterial gyrase inhibitors and uses thereof |
AU2002231244B2 (en) | 2000-12-27 | 2006-06-29 | Gilead Sciences, Inc. | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
US7490625B1 (en) | 2001-04-23 | 2009-02-17 | John Leslie Johnson | Pilot valve manifold |
US6835536B2 (en) | 2001-08-21 | 2004-12-28 | Micrologix Biotech Inc. | Antimicrobial cationic peptides and formulations thereof |
US20040037895A1 (en) * | 2002-08-23 | 2004-02-26 | Alex Zhu | Methods of treating involuntary facial spasms and facial wrinkles |
GB0230221D0 (en) * | 2002-12-24 | 2003-02-05 | South Tyneside Healthcare | Antibiotic resistance testing |
US7655646B2 (en) * | 2003-01-21 | 2010-02-02 | Thallion Pharmaceuticals, Inc. | Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals |
CA2466340C (en) * | 2003-01-21 | 2007-07-10 | Ecopia Biosciences Inc. | Farnesyl dibenzodiazepinone, processes for its production and its use as a pharmaceutical |
US20050005101A1 (en) * | 2003-07-03 | 2005-01-06 | Yenduri Bhargava K. | Kernel cryptographic module signature verification system and method |
EP1539962A4 (en) * | 2003-09-11 | 2006-12-27 | Ecopia Biosciences Inc | POLYENPOLYKETIDES AND METHODS FOR THEIR PREPARATION |
US7455840B2 (en) * | 2003-11-19 | 2008-11-25 | The Scripps Research Institute | Compositions and methods to reduce mutagenesis |
WO2007001332A2 (en) * | 2004-08-04 | 2007-01-04 | University Of Massachusetts | Anti-pathogen immunoadhesins |
US20060106028A1 (en) * | 2004-11-08 | 2006-05-18 | Ecopia Biosciences, Inc. | Polycyclic aromatics and derivatives thereof and processes for their preparation |
JP2008536495A (ja) * | 2005-04-05 | 2008-09-11 | ザ スクリップス リサーチ インスティテュート | 薬剤感受性を増強し、薬剤耐性感染症及び疾患を治療するための組成物及び方法 |
US20060241040A1 (en) * | 2005-04-06 | 2006-10-26 | Alberto Visintin | Methods of treating disorders associated with toll-like receptor 4 (TLR4) signalling |
EP2974718A1 (en) * | 2005-04-29 | 2016-01-20 | Cubist Pharmaceuticals, Inc. | Therapeutic compositions |
WO2007008904A2 (en) * | 2005-07-08 | 2007-01-18 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Targeting poly-gamma-glutamic acid to treat staphylococcus epidermidis and related infections |
EP1741440A1 (en) | 2005-07-08 | 2007-01-10 | Mellitus S.L. | Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders |
AU2008302507A1 (en) * | 2007-09-20 | 2009-03-26 | Dow Global Technologies Llc | A high throughput test method for evaluation of biocides against anaerobic microorganisms |
US9446227B2 (en) * | 2008-09-12 | 2016-09-20 | Sonescence, Inc. | Ultrasonic dispersion of compositions in tissue |
US20100069827A1 (en) | 2008-09-12 | 2010-03-18 | Barry Neil Silberg | Pre-Surgical Prophylactic Administration of Antibiotics and Therapeutic Agents |
EP2601194B1 (en) | 2010-08-03 | 2016-05-25 | Merck Sharp & Dohme Corp. | Fused-imidazoyl compounds useful as antimicrobial agents |
US8182842B1 (en) | 2010-11-10 | 2012-05-22 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Physico-chemical-managed killing of penicillin-resistant static and growing gram-positive and gram-negative vegetative bacteria |
TWI546298B (zh) | 2011-01-14 | 2016-08-21 | 維泰克斯製藥公司 | 旋轉酶及拓樸異構酶iv抑制劑 |
KR101941420B1 (ko) | 2011-06-20 | 2019-01-23 | 스페로 트리넴, 인코포레이티드 | 자이라제 및 토포이소머라제 억제제의 인산에스테르 |
WO2014015105A1 (en) | 2012-07-18 | 2014-01-23 | Vertex Pharmaceuticals Incorporated | Solid forms of (r)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1h-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
GB201319620D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Immunosuppressive agents and their use in therapy |
GB201319621D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Antimicrobial agents and their use in therapy |
AU2015236008B2 (en) * | 2014-03-25 | 2018-12-20 | Genentech, Inc. | Methods of preparing a poloxamer for use in cell culture medium |
US9956388B2 (en) | 2014-06-04 | 2018-05-01 | Sonescence, Inc. | Systems and methods for therapeutic agent delivery |
US10975131B2 (en) | 2015-10-27 | 2021-04-13 | University Of Massachusetts | Factor H-Fc immunotheraphy |
RU2678447C2 (ru) * | 2017-02-01 | 2019-01-29 | Александр Николаевич Швыдков | Способ исследования повышения антибиотикочувствительности условно-патогенной микрофлоры in vitro молочнокислой кормовой добавкой, содержащей культуру микроорганизмов streptococcus termophilus th-4 |
JP2019174077A (ja) * | 2018-03-29 | 2019-10-10 | ダイキン工業株式会社 | 薬剤入りカプセルおよび空気処理装置の部品 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE312844T1 (de) * | 1987-08-11 | 2005-12-15 | Univ New York | Biologisch-aktive bakterizide/permeabilitätserhöhende proteinbruchstücke |
US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
US5308834A (en) * | 1989-02-14 | 1994-05-03 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and prevention thereof using a BPI protein |
US5334584A (en) * | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
US5089274A (en) * | 1989-02-14 | 1992-02-18 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders |
US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
US5447914A (en) * | 1990-06-21 | 1995-09-05 | Emory University | Antimicrobial peptides |
WO1992009621A1 (en) * | 1990-12-03 | 1992-06-11 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
AU2872792A (en) * | 1991-09-26 | 1993-04-27 | Incyte Pharmaceuticals, Inc. | A new form of liposaccharide binding protein (lbp) |
CA2276548C (en) * | 1992-05-19 | 2001-07-31 | Xoma Corporation | Improved methods for the preparation of endotoxin-binding proteins |
AU4382193A (en) * | 1992-05-19 | 1993-12-13 | Xoma Corporation | BPI-immunoglobulin fusion proteins |
US5420019A (en) * | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
EP0682524B1 (en) * | 1993-02-02 | 2001-10-04 | XOMA Technology Ltd. | Pharmaceutical compositions containing bactericidal permeability increasing protein and a surfactant |
US5348942A (en) * | 1993-03-12 | 1994-09-20 | Xoma Corporation | Therapeutic uses of bactericidal/permeability increasing protein products |
ES2157981T3 (es) * | 1993-03-12 | 2001-09-01 | Xoma Technology Ltd | Usos terapeuticos de productos proteicos bactericidas/aumentadores de la permeabilidad. |
ATE169304T1 (de) * | 1993-03-12 | 1998-08-15 | Xoma Corp | Biologisch aktive peptide aus funktionellen domaenen des bakteriziden/ die permeabilitaet erhoehenden proteins und ihre verwendung |
EP0690721B1 (en) * | 1993-03-12 | 1998-05-13 | Xoma Corporation | Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products |
PT754050E (pt) * | 1994-01-14 | 2002-11-29 | Xoma Technology Ltd | Metodos e materiais contra bacterias gram-positivas |
-
1995
- 1995-01-13 PT PT95908545T patent/PT754050E/pt unknown
- 1995-01-13 CA CA002181164A patent/CA2181164C/en not_active Expired - Fee Related
- 1995-01-13 WO PCT/US1995/000656 patent/WO1995019180A1/en active IP Right Grant
- 1995-01-13 ES ES95908545T patent/ES2179095T3/es not_active Expired - Lifetime
- 1995-01-13 EP EP95908545A patent/EP0754050B1/en not_active Expired - Lifetime
- 1995-01-13 JP JP7519190A patent/JPH09508359A/ja not_active Ceased
- 1995-01-13 DE DE69527195T patent/DE69527195T2/de not_active Expired - Fee Related
- 1995-01-13 US US08/372,783 patent/US5578572A/en not_active Expired - Lifetime
- 1995-01-13 AT AT95908545T patent/ATE219684T1/de not_active IP Right Cessation
- 1995-01-13 DK DK95908545T patent/DK0754050T3/da active
- 1995-01-13 AU AU16822/95A patent/AU703192B2/en not_active Ceased
-
1996
- 1996-11-25 US US08/758,116 patent/US5783561A/en not_active Expired - Fee Related
-
1998
- 1998-07-20 US US09/119,263 patent/US6054431A/en not_active Expired - Fee Related
- 1998-12-24 HK HK98115461A patent/HK1014160A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT754050E (pt) | 2002-11-29 |
US5783561A (en) | 1998-07-21 |
DE69527195D1 (de) | 2002-08-01 |
US6054431A (en) | 2000-04-25 |
ATE219684T1 (de) | 2002-07-15 |
ES2179095T3 (es) | 2003-01-16 |
AU703192B2 (en) | 1999-03-18 |
CA2181164C (en) | 2008-01-08 |
EP0754050A1 (en) | 1997-01-22 |
HK1014160A1 (en) | 1999-09-24 |
DE69527195T2 (de) | 2003-03-06 |
EP0754050B1 (en) | 2002-06-26 |
CA2181164A1 (en) | 1995-07-20 |
AU1682295A (en) | 1995-08-01 |
WO1995019180A1 (en) | 1995-07-20 |
JPH09508359A (ja) | 1997-08-26 |
US5578572A (en) | 1996-11-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0754050T3 (da) | Anti-gram-positive bakterielle fremgangsmåder og materialer | |
CA2172245A1 (en) | Method of treating gram-negative bacterial infection by administration of bactericidal/permeability-increasing (bpi) protein | |
GEP19991538B (en) | Derivatives of Erytromycin and Pharmaceutical Composition on their Basis | |
CA2031803A1 (en) | Improvements in or relating to glycopeptide deriveratives | |
AU6339599A (en) | Quinoline derivatives and their use as antibacterial agents | |
AU8263491A (en) | Antisense oligonucleotide antibiotics complementary to the macromolecular synthesis operon, methods of treating bacterial infections and methods for identification of bacteria | |
NO991548D0 (no) | Anvendelse av mupirocin for fremstilling av et medikament for behandling av bakterieinfeksjoner forÕrsaket i forbindelse med kolonisering av nasofarynks med patogene organismer | |
FR11C0037I2 (fr) | Antibiotiques macrolides et traitement de la pasteurellose | |
MY131300A (en) | Antibacterial agents | |
AU1139992A (en) | Natural and synthetic proteins with inhibitory activity towards pathogenic microorganisms | |
AU6180294A (en) | FemA gene of staphylococcus epidermidis, femA protein, and vectors and microorganisms comprising the femA gene | |
ATE75752T1 (de) | Antibiotikum. | |
BR0016554A (pt) | Método e composição para tratamento e/ou prevenção de infecções de microorganismo resistentes à antibióticos | |
WO2004098500A3 (en) | CARBACEPHEM ss-LACTAM ANTIBIOTICS | |
ES2077584T3 (es) | Antibioticos glicopeptidos. | |
HUP0401586A2 (hu) | Baktériumellenes szer | |
ES8702428A1 (es) | Un metodo para producir antibiotico tan-588 y-o n-desacetil-antibiotico tan-588 | |
Nordmann | Antimicrobial susceptibility of human isolates of Rhodococcus equi | |
CA2468036A1 (en) | A method of treating bacterial infections using gemifloxacin or a salt thereof and a .beta.-lactam antibiotic | |
ATE222262T1 (de) | Antibiotisch wirksame stalobacine | |
SE9601901D0 (sv) | Quinine antagonists for use as a pharmaceutical | |
AU8870791A (en) | Use of temocillin or carbenicillin for the treatment or prophylaxis of bacterial infections in fish | |
ZA947394B (en) | Method of treating gram-negative bacterial infection by administration of bactericidal/permeability-increasing (BPI) protein product and antibiotic |