DK0729465T3 - Pyronderivater som proteaseinhibitorer og antivirale midler - Google Patents
Pyronderivater som proteaseinhibitorer og antivirale midlerInfo
- Publication number
- DK0729465T3 DK0729465T3 DK94932042T DK94932042T DK0729465T3 DK 0729465 T3 DK0729465 T3 DK 0729465T3 DK 94932042 T DK94932042 T DK 94932042T DK 94932042 T DK94932042 T DK 94932042T DK 0729465 T3 DK0729465 T3 DK 0729465T3
- Authority
- DK
- Denmark
- Prior art keywords
- antivirals
- pyrone derivatives
- protease inhibitors
- pyrones
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15502893A | 1993-11-19 | 1993-11-19 | |
US08/319,769 US6005103A (en) | 1993-11-19 | 1994-10-12 | Pyrone derivatives as protease inhibitors and antiviral agents |
PCT/US1994/012257 WO1995014013A1 (en) | 1993-11-19 | 1994-10-26 | Pyrone derivatives as protease inhibitors and antiviral agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0729465T3 true DK0729465T3 (da) | 2003-04-22 |
Family
ID=26851949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94932042T DK0729465T3 (da) | 1993-11-19 | 1994-10-26 | Pyronderivater som proteaseinhibitorer og antivirale midler |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0729465B1 (fi) |
JP (1) | JPH09505293A (fi) |
AT (1) | ATE231502T1 (fi) |
AU (1) | AU687465B2 (fi) |
CA (1) | CA2176044A1 (fi) |
DE (1) | DE69432056T2 (fi) |
DK (1) | DK0729465T3 (fi) |
ES (1) | ES2191035T3 (fi) |
FI (1) | FI962020L (fi) |
HR (1) | HRP940939B1 (fi) |
HU (1) | HUT77719A (fi) |
IL (1) | IL111672A0 (fi) |
NO (1) | NO315747B1 (fi) |
NZ (1) | NZ275325A (fi) |
PT (1) | PT729465E (fi) |
WO (1) | WO1995014013A1 (fi) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9609250B1 (pt) | 1995-06-28 | 2011-08-23 | 2,4,5-fenilcetoenóis trissubstituìdos, processo para sua preparação, composições para controle de pestes e herbicidas, uso das referidas composições e método para controle de pestes. | |
DE10016544A1 (de) * | 2000-04-03 | 2001-10-11 | Bayer Ag | C2-phenylsubstituierte Ketoenole |
DE10142663B4 (de) | 2001-08-31 | 2004-08-19 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-ol-Systeme |
DK2666481T3 (en) | 2003-12-26 | 2019-02-25 | Masatoshi Hagiwara | A method for regulating the phosphorylation of SR protein and antiviral agents comprising an SR protein activity regulator as the active ingredient |
CN114075161B (zh) * | 2020-08-21 | 2023-01-31 | 扬州大学附属医院 | 一种用于治疗呼吸道疾病的α-吡喃酮类化合物的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3277088A (en) * | 1963-10-03 | 1966-10-04 | Eastman Kodak Co | 4-(tertiaryamino)-2h-pyran-2-ones |
FR3724M (fr) * | 1963-12-04 | 1965-12-06 | Marcel Perrault | Médicament a base d'anisoyl-3 hydroxy-4 p. méthoxy-phényl-6α-pyrone. |
DE4308451A1 (de) * | 1992-09-10 | 1994-04-14 | Bayer Ag | 3-Aryl-pyron-Derivate |
ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
-
1994
- 1994-10-26 HU HU9601350A patent/HUT77719A/hu unknown
- 1994-10-26 DE DE69432056T patent/DE69432056T2/de not_active Expired - Fee Related
- 1994-10-26 ES ES94932042T patent/ES2191035T3/es not_active Expired - Lifetime
- 1994-10-26 AU AU80911/94A patent/AU687465B2/en not_active Ceased
- 1994-10-26 AT AT94932042T patent/ATE231502T1/de not_active IP Right Cessation
- 1994-10-26 JP JP7514457A patent/JPH09505293A/ja active Pending
- 1994-10-26 NZ NZ275325A patent/NZ275325A/xx unknown
- 1994-10-26 DK DK94932042T patent/DK0729465T3/da active
- 1994-10-26 WO PCT/US1994/012257 patent/WO1995014013A1/en active IP Right Grant
- 1994-10-26 EP EP94932042A patent/EP0729465B1/en not_active Expired - Lifetime
- 1994-10-26 PT PT94932042T patent/PT729465E/pt unknown
- 1994-10-26 CA CA002176044A patent/CA2176044A1/en not_active Abandoned
- 1994-11-17 IL IL11167294A patent/IL111672A0/xx unknown
- 1994-11-18 HR HR940939A patent/HRP940939B1/xx not_active IP Right Cessation
-
1996
- 1996-05-13 FI FI962020A patent/FI962020L/fi unknown
- 1996-05-15 NO NO19962016A patent/NO315747B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUT77719A (hu) | 1998-07-28 |
CA2176044A1 (en) | 1995-05-26 |
NO962016D0 (no) | 1996-05-15 |
EP0729465B1 (en) | 2003-01-22 |
HRP940939A2 (en) | 1997-06-30 |
DE69432056D1 (de) | 2003-02-27 |
ATE231502T1 (de) | 2003-02-15 |
IL111672A0 (en) | 1995-01-24 |
WO1995014013A1 (en) | 1995-05-26 |
JPH09505293A (ja) | 1997-05-27 |
DE69432056T2 (de) | 2003-10-09 |
NZ275325A (en) | 1999-08-30 |
NO315747B1 (no) | 2003-10-20 |
HRP940939B1 (en) | 2004-08-31 |
ES2191035T3 (es) | 2003-09-01 |
FI962020A0 (fi) | 1996-05-13 |
EP0729465A1 (en) | 1996-09-04 |
HU9601350D0 (en) | 1996-07-29 |
FI962020L (fi) | 1996-05-31 |
AU687465B2 (en) | 1998-02-26 |
NO962016L (no) | 1996-05-15 |
PT729465E (pt) | 2003-06-30 |
AU8091194A (en) | 1995-06-06 |
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