DK0719772T3 - Optisk aktivt imidazolidinonderivat og fremgangsmåde til fremstilling af samme - Google Patents
Optisk aktivt imidazolidinonderivat og fremgangsmåde til fremstilling af sammeInfo
- Publication number
- DK0719772T3 DK0719772T3 DK94926387T DK94926387T DK0719772T3 DK 0719772 T3 DK0719772 T3 DK 0719772T3 DK 94926387 T DK94926387 T DK 94926387T DK 94926387 T DK94926387 T DK 94926387T DK 0719772 T3 DK0719772 T3 DK 0719772T3
- Authority
- DK
- Denmark
- Prior art keywords
- same
- producing
- optically active
- imidazolidinone derivative
- active imidazolidinone
- Prior art date
Links
- 150000008624 imidazolidinones Chemical class 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000001713 cholinergic effect Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- -1 nitro, amino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25498393 | 1993-09-17 | ||
| JP24226494A JP3916093B2 (ja) | 1993-09-17 | 1994-09-09 | 光学活性イミダゾリジノン誘導体とその製造方法 |
| PCT/JP1994/001505 WO1995007905A1 (fr) | 1993-09-17 | 1994-09-12 | Derive d'imidazolidinone et procede pour sa production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0719772T3 true DK0719772T3 (da) | 2000-11-06 |
Family
ID=26535688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94926387T DK0719772T3 (da) | 1993-09-17 | 1994-09-12 | Optisk aktivt imidazolidinonderivat og fremgangsmåde til fremstilling af samme |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5726188A (da) |
| EP (1) | EP0719772B1 (da) |
| JP (1) | JP3916093B2 (da) |
| KR (1) | KR100323930B1 (da) |
| CN (1) | CN1041088C (da) |
| AT (1) | ATE194611T1 (da) |
| AU (1) | AU679259B2 (da) |
| CA (1) | CA2172162C (da) |
| DE (1) | DE69425266T2 (da) |
| DK (1) | DK0719772T3 (da) |
| ES (1) | ES2149281T3 (da) |
| GR (1) | GR3034499T3 (da) |
| HU (1) | HU217668B (da) |
| PT (1) | PT719772E (da) |
| WO (1) | WO1995007905A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0719264B1 (en) * | 1993-09-15 | 1997-12-29 | Merck Sharp & Dohme Ltd. | Imidazolone and oxazolone derivatives as dopamine antagonists |
| US6159990A (en) * | 1997-06-18 | 2000-12-12 | Synaptic Pharmaceutical Corporation | Oxazolidinones as α1A receptor antagonists |
| US6316623B1 (en) * | 1998-08-21 | 2001-11-13 | Isis Pharmaceuticals, Inc. | Ethylenediamine compound libraries |
| CA2457647A1 (en) * | 2001-10-02 | 2003-04-10 | Acadia Pharmaceuticals, Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| US6951849B2 (en) * | 2001-10-02 | 2005-10-04 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| JP5209481B2 (ja) * | 2005-09-30 | 2013-06-12 | グラクソ グループ リミテッド | Ｍ１受容体にて活性を有する化合物および医薬におけるそれらの使用 |
| US8288413B2 (en) * | 2005-09-30 | 2012-10-16 | Glaxo Group Limited | Benzimidazolones which have activity at M1 receptor |
| WO2007036715A2 (en) * | 2005-09-30 | 2007-04-05 | Glaxo Group Limited | Compounds which have activity at m1 receptor and their uses in medicine |
| US8338142B2 (en) * | 2007-02-19 | 2012-12-25 | Kaneka Corporation | Method for producing optically active 3-aminopiperidine or salt thereof |
| US20120123128A1 (en) * | 2009-07-21 | 2012-05-17 | Sumitomo Chemical Company, Limited | Process for production of optically active nipecotamide |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3196152A (en) * | 1965-07-20 | Phenyl and alkyleneamino substituted imidazolidinones and salts thereof | ||
| US459757A (en) * | 1891-09-22 | Electric-arc lamp | ||
| US3355457A (en) * | 1965-05-21 | 1967-11-28 | American Cyanamid Co | Substituted 2-imidazolinones |
| US3459757A (en) * | 1965-10-22 | 1969-08-05 | American Cyanamid Co | Imidazolidines |
| US4011238A (en) * | 1972-07-26 | 1977-03-08 | Gruppo Lepetit S.P.A. | 2-imidazolidione derivatives |
| GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
| US5300515A (en) * | 1991-01-31 | 1994-04-05 | Kyorin Pharmaceutical Co., Ltd. | Carbamic acid derivatives and method for preparing the same |
| EP0719264B1 (en) * | 1993-09-15 | 1997-12-29 | Merck Sharp & Dohme Ltd. | Imidazolone and oxazolone derivatives as dopamine antagonists |
-
1994
- 1994-09-09 JP JP24226494A patent/JP3916093B2/ja not_active Expired - Fee Related
- 1994-09-12 US US08/612,827 patent/US5726188A/en not_active Expired - Fee Related
- 1994-09-12 WO PCT/JP1994/001505 patent/WO1995007905A1/ja active IP Right Grant
- 1994-09-12 CN CN94194134A patent/CN1041088C/zh not_active Expired - Fee Related
- 1994-09-12 KR KR1019960701412A patent/KR100323930B1/ko not_active IP Right Cessation
- 1994-09-12 ES ES94926387T patent/ES2149281T3/es not_active Expired - Lifetime
- 1994-09-12 CA CA002172162A patent/CA2172162C/en not_active Expired - Fee Related
- 1994-09-12 AU AU76243/94A patent/AU679259B2/en not_active Ceased
- 1994-09-12 EP EP94926387A patent/EP0719772B1/en not_active Expired - Lifetime
- 1994-09-12 PT PT94926387T patent/PT719772E/pt unknown
- 1994-09-12 DE DE69425266T patent/DE69425266T2/de not_active Expired - Fee Related
- 1994-09-12 AT AT94926387T patent/ATE194611T1/de not_active IP Right Cessation
- 1994-09-12 DK DK94926387T patent/DK0719772T3/da active
- 1994-09-12 HU HU9600622A patent/HU217668B/hu not_active IP Right Cessation
-
2000
- 2000-09-28 GR GR20000402189T patent/GR3034499T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100323930B1 (ko) | 2004-05-06 |
| PT719772E (pt) | 2000-11-30 |
| DE69425266T2 (de) | 2001-02-22 |
| ATE194611T1 (de) | 2000-07-15 |
| AU679259B2 (en) | 1997-06-26 |
| KR960704878A (ko) | 1996-10-09 |
| JP3916093B2 (ja) | 2007-05-16 |
| EP0719772A1 (en) | 1996-07-03 |
| HU9600622D0 (en) | 1996-05-28 |
| WO1995007905A1 (fr) | 1995-03-23 |
| CA2172162A1 (en) | 1995-03-23 |
| CN1041088C (zh) | 1998-12-09 |
| CN1135216A (zh) | 1996-11-06 |
| EP0719772B1 (en) | 2000-07-12 |
| GR3034499T3 (en) | 2000-12-29 |
| EP0719772A4 (en) | 1996-09-04 |
| AU7624394A (en) | 1995-04-03 |
| ES2149281T3 (es) | 2000-11-01 |
| HU217668B (hu) | 2000-03-28 |
| US5726188A (en) | 1998-03-10 |
| CA2172162C (en) | 2005-04-19 |
| JPH07133273A (ja) | 1995-05-23 |
| HUT75649A (en) | 1997-05-28 |
| DE69425266D1 (de) | 2000-08-17 |
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