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DK0699439T3 - Behandling af sygdomme forårsaget af talgkirtellidelser med acyl-CoA-cholesterolacyltransferaseinhibitorer - Google Patents

Behandling af sygdomme forårsaget af talgkirtellidelser med acyl-CoA-cholesterolacyltransferaseinhibitorer

Info

Publication number
DK0699439T3
DK0699439T3 DK95305594T DK95305594T DK0699439T3 DK 0699439 T3 DK0699439 T3 DK 0699439T3 DK 95305594 T DK95305594 T DK 95305594T DK 95305594 T DK95305594 T DK 95305594T DK 0699439 T3 DK0699439 T3 DK 0699439T3
Authority
DK
Denmark
Prior art keywords
acyl
diseases caused
sebaceous gland
cholesterolacyltransferase
coa
Prior art date
Application number
DK95305594T
Other languages
English (en)
Inventor
James T Mayne
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0699439T3 publication Critical patent/DK0699439T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
DK95305594T 1994-08-31 1995-08-10 Behandling af sygdomme forårsaget af talgkirtellidelser med acyl-CoA-cholesterolacyltransferaseinhibitorer DK0699439T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/298,735 US6133326A (en) 1994-08-31 1994-08-31 Compositions and methods for decreasing sebum production

Publications (1)

Publication Number Publication Date
DK0699439T3 true DK0699439T3 (da) 1999-12-27

Family

ID=23151816

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95305594T DK0699439T3 (da) 1994-08-31 1995-08-10 Behandling af sygdomme forårsaget af talgkirtellidelser med acyl-CoA-cholesterolacyltransferaseinhibitorer

Country Status (9)

Country Link
US (2) US6133326A (da)
EP (1) EP0699439B1 (da)
JP (2) JP3266473B2 (da)
AT (1) ATE185271T1 (da)
CA (1) CA2157142C (da)
DE (1) DE69512589T2 (da)
DK (1) DK0699439T3 (da)
ES (1) ES2136252T3 (da)
GR (1) GR3031917T3 (da)

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US6080408A (en) * 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
CN1195550C (zh) * 1998-12-28 2005-04-06 大正制药株式会社 外用剂
US20030077301A1 (en) * 1999-12-16 2003-04-24 Maibach Howard I. Topical pharmaceutical composition for the treatment of inflammatory dermatoses
IL150865A0 (en) * 2000-02-02 2003-02-12 Warner Lambert Co Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders
IL159156A0 (en) * 2001-06-22 2004-06-01 Millard Marsden Mershon A gel forming composition containing a polyacrylic acid
EP1281399A3 (en) * 2001-08-01 2004-02-11 Warner-Lambert Company Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
CA2478237C (en) * 2002-03-12 2009-05-12 Michael Graeber Use of adapalene for the treatment of dermatological disorders
JP2009102358A (ja) * 2003-07-29 2009-05-14 Rohto Pharmaceut Co Ltd 皮膚外用剤
JP2005060386A (ja) * 2003-07-29 2005-03-10 Rohto Pharmaceut Co Ltd 皮膚外用剤
KR100786436B1 (ko) 2003-10-09 2007-12-17 워너-램버트 캄파니 엘엘씨 피지 생성을 감소시키기 위한 말론아마이드 유도체를포함하는 약학 조성물
KR100906288B1 (ko) * 2005-02-24 2009-07-06 워너-램버트 캄파니 엘엘씨 결정질 acat 억제제
FR2918890A1 (fr) * 2007-07-19 2009-01-23 Galderma Res & Dev Utilisation du pactimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal
FR2918889B1 (fr) * 2007-07-19 2009-10-23 Galderma Res & Dev Utilisation de l'eflucimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal
FR2920771B1 (fr) * 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de phenylurees, inhibiteurs de l'enzymes soat-1, compositions pharmaceutiques et cosmetiques les contenant
FR2920769B1 (fr) 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de n-phenyl acetamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant
CN101502541B (zh) * 2008-02-04 2011-12-28 成都地奥九泓制药厂 安息香属植物及其提取物的用途
FR2946342B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux derives de dioxo-imidazolidine, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
FR2946340B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux n-phenyl acetamie, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
FR2946346B1 (fr) 2009-06-05 2011-05-20 Galderma Res & Dev Nouveaux derives dioxo-imidazolidine, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
FR2946345B1 (fr) 2009-06-05 2011-05-20 Galderma Res & Dev Nouveaux derives dioxo-imidazolidine, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
US11865113B2 (en) 2016-06-06 2024-01-09 Lipidio Pharmaceuticals Inc. Methods of treating a patient afflicted with non-alcoholic steatohepatitis (NASH)

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LU86258A1 (fr) 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
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US4743605A (en) 1987-02-24 1988-05-10 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-coa:cholesterol acyltransferase
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US6001860A (en) * 1992-05-28 1999-12-14 Pfizer Inc. N-aryl and N-heteroarylurea derivatives as inhibitors of acyl coenzyme A: Cholesterol acyl transferase (ACAT)
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US5994330A (en) * 1998-11-09 1999-11-30 El Khoury; Georges F. Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions
US9206485B2 (en) 2011-08-19 2015-12-08 J. Edwin Roy Portable sugar mill
US9303539B1 (en) 2012-06-10 2016-04-05 Ags I-Prop, Llc Universal drain plug system and method
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Also Published As

Publication number Publication date
ES2136252T3 (es) 1999-11-16
US6271268B1 (en) 2001-08-07
DE69512589T2 (de) 2000-01-27
CA2157142C (en) 1998-06-09
JP3266473B2 (ja) 2002-03-18
ATE185271T1 (de) 1999-10-15
JPH0899903A (ja) 1996-04-16
CA2157142A1 (en) 1996-03-01
GR3031917T3 (en) 2000-03-31
DE69512589D1 (de) 1999-11-11
US6133326A (en) 2000-10-17
EP0699439A2 (en) 1996-03-06
EP0699439B1 (en) 1999-10-06
EP0699439A3 (en) 1996-06-26
JP2002053494A (ja) 2002-02-19

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