DK0691980T3 - 7-deazapurinmodifiderende oligonukleotider - Google Patents
7-deazapurinmodifiderende oligonukleotiderInfo
- Publication number
- DK0691980T3 DK0691980T3 DK94913923.2T DK94913923T DK0691980T3 DK 0691980 T3 DK0691980 T3 DK 0691980T3 DK 94913923 T DK94913923 T DK 94913923T DK 0691980 T3 DK0691980 T3 DK 0691980T3
- Authority
- DK
- Denmark
- Prior art keywords
- deazapurine
- oligonucleotides
- modifying oligonucleotides
- modifying
- deazanucleosides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4015893A | 1993-03-30 | 1993-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0691980T3 true DK0691980T3 (da) | 1997-12-29 |
Family
ID=21909441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94913923.2T DK0691980T3 (da) | 1993-03-30 | 1994-03-21 | 7-deazapurinmodifiderende oligonukleotider |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0691980B1 (da) |
| JP (1) | JPH08508493A (da) |
| AT (1) | ATE154029T1 (da) |
| AU (1) | AU6589094A (da) |
| CA (1) | CA2159630A1 (da) |
| DE (1) | DE69403642T2 (da) |
| DK (1) | DK0691980T3 (da) |
| ES (1) | ES2105698T3 (da) |
| GR (1) | GR3024597T3 (da) |
| HU (1) | HU9501963D0 (da) |
| WO (1) | WO1994022892A1 (da) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4438918A1 (de) * | 1994-11-04 | 1996-05-09 | Hoechst Ag | Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung |
| US6150510A (en) | 1995-11-06 | 2000-11-21 | Aventis Pharma Deutschland Gmbh | Modified oligonucleotides, their preparation and their use |
| US6906185B1 (en) | 1997-03-20 | 2005-06-14 | Amersham Biosciences Corp. | Derivatives of 7-deaza -2′-deoxyguanosine-5'-triphosphate, preparation and use thereof |
| GB2323357B (en) * | 1997-03-20 | 1999-09-29 | Amersham Pharm Biotech Inc | Derivatives of 7-deaza-2-deoxy-guanosine-5'-triphosphate, preparation and use thereof |
| US6660845B1 (en) * | 1999-11-23 | 2003-12-09 | Epoch Biosciences, Inc. | Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof |
| US6962906B2 (en) | 2000-03-14 | 2005-11-08 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
| US7115738B2 (en) | 2000-03-14 | 2006-10-03 | Active Motif | Hydroxyproline/phosphono oligonucleotide analogues, methods of synthesis and methods of use |
| KR100894767B1 (ko) * | 2000-09-26 | 2009-04-24 | 이데라 파마슈티칼즈, 인코포레이티드 | 화학적인 위치 변화에 의해 면역자극 올리고누클레오티드유사체의 면역자극 활성을 조절하는 방법 |
| EP2171088B1 (en) | 2007-06-19 | 2015-10-14 | Stratos Genomics Inc. | High throughput nucleic acid sequencing by expansion |
| EP2391726B1 (en) | 2009-01-29 | 2015-09-23 | Stratos Genomics Inc. | High throughput nucleic acid sequencing by expansion and related methods |
| US8586301B2 (en) | 2010-06-30 | 2013-11-19 | Stratos Genomics, Inc. | Multiplexed identification of nucleic acid sequences |
| US9212392B2 (en) | 2012-09-25 | 2015-12-15 | Exact Sciences Corporation | Normalization of polymerase activity |
| US20140287946A1 (en) | 2013-03-14 | 2014-09-25 | Ibis Biosciences, Inc. | Nucleic acid control panels |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| US10301345B2 (en) | 2014-11-20 | 2019-05-28 | Stratos Genomics, Inc. | Phosphoroamidate esters, and use and synthesis thereof |
| WO2017075061A1 (en) | 2015-10-30 | 2017-05-04 | Exact Sciences Corporation | Multiplex amplification detection assay and isolation and detection of dna from plasma |
| ES2846949T3 (es) | 2015-11-16 | 2021-07-30 | Stratos Genomics Inc | Variantes de la polimerasa DPO4 |
| AU2017260630B2 (en) | 2016-05-05 | 2023-07-13 | Exact Sciences Corporation | Detection of lung neoplasia by analysis of methylated DNA |
| JP7289264B2 (ja) | 2017-01-27 | 2023-06-09 | エグザクト サイエンシーズ コーポレーション | メチル化ｄｎａの分析による結腸腫瘍の検出 |
| JP7095893B2 (ja) | 2017-02-21 | 2022-07-05 | 国立大学法人大阪大学 | アンチセンスオリゴ核酸 |
| US11708566B2 (en) | 2017-05-04 | 2023-07-25 | Stratos Genomics, Inc. | DP04 polymerase variants |
| US11530392B2 (en) | 2017-12-11 | 2022-12-20 | Stratos Genomics, Inc. | DPO4 polymerase variants with improved accuracy |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| US20220403450A1 (en) | 2021-06-03 | 2022-12-22 | Illumina Software, Inc. | Systems and methods for sequencing nucleotides using two optical channels |
| CN118056130A (zh) | 2021-07-01 | 2024-05-17 | 因美纳有限公司 | 用于纳米孔测序的具有水平纳米通道的装置 |
| EP4396376A1 (en) | 2021-09-01 | 2024-07-10 | Illumina, Inc. | Amplitude modulation for accelerated base calling |
| AU2022349615A1 (en) | 2021-09-22 | 2024-01-18 | Illumina, Inc. | Sequencing polynucleotides using nanopores |
| US20230112203A1 (en) | 2021-09-30 | 2023-04-13 | Illumina, Inc. | Isolation of cells in a nanopore sensor array |
| US20240319165A1 (en) | 2021-11-15 | 2024-09-26 | Illumina, Inc. | Nanopore systems and methods of fabrication |
| WO2023107622A1 (en) | 2021-12-10 | 2023-06-15 | Illumina, Inc. | Parallel sample and index sequencing |
| WO2023175041A1 (en) | 2022-03-15 | 2023-09-21 | Illumina, Inc. | Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides |
| US20230357307A1 (en) | 2022-05-04 | 2023-11-09 | Illumina, Inc. | Cleavable cyclic loop nucleotides for nanopore sequencing |
| CN119301684A (zh) | 2022-06-07 | 2025-01-10 | 因美纳有限公司 | 用于鉴定基因变体的方法和系统 |
| KR20250036077A (ko) | 2022-07-07 | 2025-03-13 | 일루미나, 인코포레이티드 | 카피수 변이체 유전자형을 결정하기 위한 방법 및 시스템 |
| KR20250034300A (ko) | 2022-07-07 | 2025-03-11 | 일루미나, 인코포레이티드 | 재조합 이벤트를 검출하기 위한 방법 및 시스템 |
| WO2024073278A1 (en) | 2022-09-26 | 2024-04-04 | Illumina, Inc. | Detecting and genotyping variable number tandem repeats |
| US20240110889A1 (en) | 2022-09-28 | 2024-04-04 | Illumina, Inc. | Fast pulsing for nanopore sensors |
| CN118946933A (zh) | 2023-01-31 | 2024-11-12 | 因美纳有限公司 | 拷贝数变体调用和恢复 |
| CN119404254A (zh) | 2023-03-10 | 2025-02-07 | 因美纳有限公司 | 用于组装多核苷酸序列的基于k-mer的方法 |
| WO2024228928A1 (en) | 2023-05-03 | 2024-11-07 | Illumina, Inc. | Controlled polynucleotide translocation in nanopore sequencing |
| WO2024249253A1 (en) | 2023-05-31 | 2024-12-05 | Illumina, Inc. | Detecting tandem repeats and determining copy numbers thereof |
| WO2025006466A1 (en) | 2023-06-30 | 2025-01-02 | Illumina, Inc. | Systems and methods of sequencing polynucleotides with four labeled nucleotides |
| WO2025006464A1 (en) | 2023-06-30 | 2025-01-02 | Illumina, Inc. | Systems and methods of sequencing polynucleotides with alternative scatterplots |
| WO2025006460A1 (en) | 2023-06-30 | 2025-01-02 | Illumina, Inc. | Systems and methods of sequencing polynucleotides with modified bases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3739366A1 (de) * | 1987-04-10 | 1988-10-27 | Boehringer Mannheim Gmbh | Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel |
-
1994
- 1994-03-21 DK DK94913923.2T patent/DK0691980T3/da active
- 1994-03-21 ES ES94913923T patent/ES2105698T3/es not_active Expired - Lifetime
- 1994-03-21 AT AT94913923T patent/ATE154029T1/de not_active IP Right Cessation
- 1994-03-21 JP JP6522134A patent/JPH08508493A/ja active Pending
- 1994-03-21 HU HU9501963A patent/HU9501963D0/hu unknown
- 1994-03-21 CA CA002159630A patent/CA2159630A1/en not_active Abandoned
- 1994-03-21 AU AU65890/94A patent/AU6589094A/en not_active Abandoned
- 1994-03-21 EP EP94913923A patent/EP0691980B1/en not_active Expired - Lifetime
- 1994-03-21 WO PCT/US1994/002996 patent/WO1994022892A1/en active IP Right Grant
- 1994-03-21 DE DE69403642T patent/DE69403642T2/de not_active Expired - Fee Related
-
1997
- 1997-09-02 GR GR970402241T patent/GR3024597T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0691980A1 (en) | 1996-01-17 |
| DE69403642D1 (de) | 1997-07-10 |
| DE69403642T2 (de) | 1998-01-08 |
| AU6589094A (en) | 1994-10-24 |
| ATE154029T1 (de) | 1997-06-15 |
| GR3024597T3 (en) | 1997-12-31 |
| JPH08508493A (ja) | 1996-09-10 |
| EP0691980B1 (en) | 1997-06-04 |
| HU9501963D0 (en) | 1995-08-28 |
| ES2105698T3 (es) | 1997-10-16 |
| CA2159630A1 (en) | 1994-10-13 |
| WO1994022892A1 (en) | 1994-10-13 |
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