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DK0639976T3 - Anvendelse af terfenadin-derivater som antihistaminika i patienter med leversygdomme - Google Patents

Anvendelse af terfenadin-derivater som antihistaminika i patienter med leversygdomme

Info

Publication number
DK0639976T3
DK0639976T3 DK93909249T DK93909249T DK0639976T3 DK 0639976 T3 DK0639976 T3 DK 0639976T3 DK 93909249 T DK93909249 T DK 93909249T DK 93909249 T DK93909249 T DK 93909249T DK 0639976 T3 DK0639976 T3 DK 0639976T3
Authority
DK
Denmark
Prior art keywords
hydrogen
antihistamines
patients
liver disease
hydroxy
Prior art date
Application number
DK93909249T
Other languages
English (en)
Inventor
James K Woodward
Richard R Okerholm
Mark G Eller
Bruce E Mcnutt
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27128589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0639976(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of DK0639976T3 publication Critical patent/DK0639976T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK93909249T 1992-05-11 1993-04-06 Anvendelse af terfenadin-derivater som antihistaminika i patienter med leversygdomme DK0639976T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88080192A 1992-05-11 1992-05-11
US92289092A 1992-07-31 1992-07-31
PCT/US1993/003151 WO1993023047A1 (en) 1992-05-11 1993-04-06 Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient

Publications (1)

Publication Number Publication Date
DK0639976T3 true DK0639976T3 (da) 1999-02-15

Family

ID=27128589

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93909249T DK0639976T3 (da) 1992-05-11 1993-04-06 Anvendelse af terfenadin-derivater som antihistaminika i patienter med leversygdomme

Country Status (16)

Country Link
US (7) US6037353A (da)
EP (1) EP0639976B1 (da)
JP (1) JPH07506828A (da)
KR (1) KR950701525A (da)
AT (1) ATE194913T1 (da)
AU (1) AU679910B2 (da)
CA (1) CA2134211C (da)
CL (1) CL2004000304A1 (da)
DE (1) DE69320952T2 (da)
DK (1) DK0639976T3 (da)
ES (1) ES2121084T3 (da)
HU (1) HU223774B1 (da)
MX (1) MX9302704A (da)
NO (1) NO307688B1 (da)
NZ (1) NZ251834A (da)
WO (1) WO1993023047A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023047A1 (en) * 1992-05-11 1993-11-25 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
KR950702420A (ko) * 1992-08-03 1995-07-29 데이비드 사무소 웰 알레르기 질환 치료를 위한 테르페나딘 대사물과 그것의 광학 순수 이성체(terfenadine metabolites and their optically pure isomers for treating allergic disorders)
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
EP0766668B1 (en) * 1994-05-18 2002-07-17 Aventis Pharmaceuticals Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
WO1996026726A1 (en) * 1995-02-28 1996-09-06 Hoechst Marion Roussel, Inc. Pharmaceutical composition for piperidinoalkanol compounds
UA60335C2 (uk) * 1997-08-26 2003-10-15 Хехст Маріон Рассел, Інк. Фармацевтична композиція, яка об'єднує піперидиноалканол з протинабряковим агентом
US6194431B1 (en) 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
SK13822003A3 (sk) * 2001-04-09 2004-09-08 Teva Pharmaceutical Industries Ltd. Polymorfné formy chloridu fexofenadínu
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
US20040044038A1 (en) * 2002-06-10 2004-03-04 Barnaba Krochmal Polymorphic form XVI of fexofenadine hydrochloride
EP1393728A1 (en) * 2002-08-30 2004-03-03 Vrije Universiteit Inverse agonists acting at virus-encoded G protein-coupled receptors
US20050065183A1 (en) * 2003-07-31 2005-03-24 Indranil Nandi Fexofenadine composition and process for preparing
EP1628959A2 (en) * 2004-04-26 2006-03-01 Teva Pharmaceutical Industries Ltd Crystalline forms of fexofenadine hydrochloride and processes for their preparation
JP2008514641A (ja) * 2004-09-28 2008-05-08 テバ ファーマシューティカル インダストリーズ リミティド 結晶形フェキソフェナジン、およびその調製方法
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
WO2009158144A1 (en) * 2008-05-30 2009-12-30 Fairfield Clinical Trials Llc Method and composition for dermatoses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4285958A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkylene ketones, pharmaceutical compositions thereof and method of use thereof
AR240018A1 (es) * 1987-10-07 1990-01-31 Merrell Pharma Inc Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
US4929605A (en) * 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
WO1993023047A1 (en) * 1992-05-11 1993-11-25 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
KR950702420A (ko) * 1992-08-03 1995-07-29 데이비드 사무소 웰 알레르기 질환 치료를 위한 테르페나딘 대사물과 그것의 광학 순수 이성체(terfenadine metabolites and their optically pure isomers for treating allergic disorders)

Also Published As

Publication number Publication date
CA2134211A1 (en) 1993-11-25
EP0639976B1 (en) 2000-07-26
NO944287D0 (no) 1994-11-10
NO944287L (no) 1994-11-10
US6037353A (en) 2000-03-14
US20100168166A1 (en) 2010-07-01
KR950701525A (ko) 1995-04-28
NZ251834A (en) 1997-07-27
EP0639976A1 (en) 1995-03-01
US20030130315A1 (en) 2003-07-10
ATE194913T1 (de) 2000-08-15
NO307688B1 (no) 2000-05-15
US6399632B1 (en) 2002-06-04
HUT71402A (en) 1995-11-28
DE69320952D1 (de) 1998-10-15
CL2004000304A1 (es) 2005-05-27
DE69320952T2 (de) 1999-05-27
AU679910B2 (en) 1997-07-17
WO1993023047A1 (en) 1993-11-25
HU223774B1 (hu) 2005-01-28
US20060205782A1 (en) 2006-09-14
US6187791B1 (en) 2001-02-13
US20030055083A1 (en) 2003-03-20
MX9302704A (es) 1994-06-30
AU3973493A (en) 1993-12-13
JPH07506828A (ja) 1995-07-27
ES2121084T3 (es) 2002-02-16
CA2134211C (en) 1999-06-29

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